Preclinical characterization of A-582941: a novel alpha7 neuronal nicotinic receptor agonist with broad spectrum cognition-enhancing properties (Q34778803)

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English	Preclinical characterization of A-582941: a novel alpha7 neuronal nicotinic receptor agonist with broad spectrum cognition-enhancing properties	scientific article

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scholarly article

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4 August 2017

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Preclinical characterization of A-582941: a novel alpha7 neuronal nicotinic receptor agonist with broad spectrum cognition-enhancing properties (English)

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4 August 2017

author name string

Karin R Tietje

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David J Anderson

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R Scott Bitner

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Eric A Blomme

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Paul J Brackemeyer

5

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Clark A Briggs

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Kaitlin E Browman

7

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Dagmar Bury

8

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Peter Curzon

9

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Karla U Drescher

10

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Jennifer M Frost

11

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Ryan M Fryer

12

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Gerard B Fox

13

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Jens Halvard Gronlien

14

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Monika Håkerud

15

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Earl J Gubbins

16

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Sabine Halm

17

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Richard Harris

18

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Rosalind J Helfrich

19

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Kathy L Kohlhaas

20

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Devalina Law

21

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John Malysz

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Kennan C Marsh

23

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Ruth L Martin

24

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Michael D Meyer

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Angela L Molesky

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Arthur L Nikkel

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Stephani Otte

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Liping Pan

29

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Pamela S Puttfarcken

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Richard J Radek

31

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Holly M Robb

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Eva Spies

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Kirsten Thorin-Hagene

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Jeffrey F Waring

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Hilde Ween

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Hongyu Xu

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Murali Gopalakrishnan

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William H Bunnelle

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publication date

1 January 2008

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CNS Neuroscience & Therapeutics

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14

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1

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65-82

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4 August 2017

Molecular psychology: roles for the ERK MAP kinase cascade in memory

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[3H]A-585539 [(1S,4S)-2,2-dimethyl-5-(6-phenylpyridazin-3-yl)-5-aza-2-azoniabicyclo[2.2.1]heptane], a novel high-affinity alpha7 neuronal nicotinic receptor agonist: radioligand binding characterization to rat and human brain

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Broad-spectrum efficacy across cognitive domains by alpha7 nicotinic acetylcholine receptor agonism correlates with activation of ERK1/2 and CREB phosphorylation pathways

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Antisense knockdown of the rat alpha7 nicotinic acetylcholine receptor produces spatial memory impairment

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Transdermal nicotine and haloperidol in Tourette's disorder: a double-blind placebo-controlled study.

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Impaired attention is central to the cognitive deficits observed in alpha 7 deficient mice

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Identifiers

10.1111/J.1755-5949.2008.00037.X

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

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