High Fat Diet Induces Liver Steatosis and Early Dysregulation of Iron Metabolism in Rats (Q34785418)

4 August 2017

High Fat Diet Induces Liver Steatosis and Early Dysregulation of Iron Metabolism in Rats (English)

1 reference

4 August 2017

1 reference

Rosaria Meli

1

1 reference

4 August 2017

Giuseppina Mattace Raso

2

1 reference

4 August 2017

Carlo Irace

3

1 reference

4 August 2017

Raffaele Simeoli

4

1 reference

4 August 2017

Antonio Di Pascale

5

1 reference

4 August 2017

Orlando Paciello

6

1 reference

4 August 2017

Teresa Bruna Pagano

7

1 reference

4 August 2017

Antonio Calignano

8

1 reference

4 August 2017

Alfredo Colonna

9

1 reference

4 August 2017

Rita Santamaria

10

1 reference

4 August 2017

language of work or name

English

0 references

publication date

21 June 2013

1 reference

4 August 2017

1 reference

4 August 2017

8

1 reference

4 August 2017

e66570

1 reference

4 August 2017

6

1 reference

Creative Commons Attribution 4.0 International

4 August 2017

start time

21 June 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Iron sensing and signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689747

Accelerated CCl4-induced liver fibrosis in Hjv-/- mice, associated with an oxidative burst and precocious profibrogenic gene expression

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689747

Serum ferritin is an independent predictor of histologic severity and advanced fibrosis in patients with nonalcoholic fatty liver disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689747

Regulation of cellular iron metabolism

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689747

Hepcidin and iron regulation, 10 years later

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689747

Relationship between the pattern of hepatic iron deposition and histological severity in nonalcoholic fatty liver disease.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689747

Evolution of inflammation in nonalcoholic fatty liver disease: the multiple parallel hits hypothesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689747

Tumorigenic properties of iron regulatory protein 2 (IRP2) mediated by its specific 73-amino acids insert

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689747

Iron regulatory proteins: from molecular mechanisms to drug development

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689747

The role of hepcidin in iron metabolism

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689747

An E3 ligase possessing an iron-responsive hemerythrin domain is a regulator of iron homeostasis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689747

Control of iron homeostasis by an iron-regulated ubiquitin ligase

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689747

Adipokines in nonalcoholic steatohepatitis: from pathogenesis to implications in diagnosis and therapy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689747

Ferritin functions as a proinflammatory cytokine via iron-independent protein kinase C zeta/nuclear factor kappaB-regulated signaling in rat hepatic stellate cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689747

Expression of iron-related proteins during infection by bovine herpes virus type-1.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689747

Distinct C/EBPalpha motifs regulate lipogenic and gluconeogenic gene expression in vivo

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689747

A model of insulin resistance and nonalcoholic steatohepatitis in rats: role of peroxisome proliferator-activated receptor-alpha and n-3 polyunsaturated fatty acid treatment on liver injury.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689747

Molecular control of vertebrate iron homeostasis by iron regulatory proteins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689747

Liver diseases in the hemochromatosis and iron overload screening study.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689747

Divergent modulation of iron regulatory proteins and ferritin biosynthesis by hypoxia/reoxygenation in neurones and glial cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689747

Iron release from macrophages after erythrophagocytosis is up-regulated by ferroportin 1 overexpression and down-regulated by hepcidin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689747

Mammalian tissue oxygen levels modulate iron-regulatory protein activities in vivo

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689747

Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689747

IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689747

Induction of ferritin expression by oxalomalate

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689747

Estrogen and raloxifene modulate leptin and its receptor in hypothalamus and adipose tissue from ovariectomized rats

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689747

Interaction of iron, insulin resistance, and nonalcoholic steatohepatitis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689747

Hepcidin, a putative mediator of anemia of inflammation, is a type II acute-phase protein

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689747

The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689747

C/EBPalpha regulates hepatic transcription of hepcidin, an antimicrobial peptide and regulator of iron metabolism. Cross-talk between C/EBP pathway and iron metabolism

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689747

Nonalcoholic fatty liver disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689747

Hepcidin, a urinary antimicrobial peptide synthesized in the liver

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689747

Overexpression of H ferritin and up-regulation of iron regulatory protein genes during differentiation of 3T3-L1 pre-adipocytes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689747

Iron, free radicals, and oxidative injury

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689747

Differences in the regulation of iron regulatory protein-1 (IRP-1) by extra- and intracellular oxidative stress

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689747

Assessment of iron status

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689747

The ferritins: molecular properties, iron storage function and cellular regulation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689747

The stimulus-sensitive H2O2-generating system present in human fat-cell plasma membranes is multireceptor-linked and under antagonistic control by hormones and cytokines

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689747

Biosynthesis of nitric oxide activates iron regulatory factor in macrophages

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689747

Iron regulates ferritin mRNA translation through a segment of its 5' untranslated region

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689747

A specific mRNA binding factor regulates the iron-dependent stability of cytoplasmic transferrin receptor mRNA.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689747

Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689747

Histologic features of the liver in insulin resistance-associated iron overload. A study of 139 patients

7 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0066570

Ovariectomy and estrogen treatment modulate iron metabolism in rat adipose tissue.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0066570

IRP1 activation by extracellular oxidative stress in the perfused rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0066570

Relative contribution of iron burden, HFE mutations, and insulin resistance to fibrosis in nonalcoholic fatty liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0066570

Antagonistic effects of different members of the fibroblast and platelet-derived growth factor families on adipose conversion and NADPH-dependent H2O2 generation in 3T3 L1-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0066570

Serum ferritin is derived primarily from macrophages through a nonclassical secretory pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0066570

Effect of hepcidin on intestinal iron absorption in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0066570

Dietary fat level affects tissue iron levels but not the iron regulatory gene HAMP in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0066570

Diet-induced obesity leads to decreased hepatic iron storage in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0066570

Involvement of hepcidin in the anemia of multiple myeloma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0066570

The prevalence and etiology of elevated aminotransferase levels in the United States

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689747

High-fat diet causes iron deficiency via hepcidin-independent reduction of duodenal iron absorption

26 October 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0066570

Iron in NASH, chronic liver diseases and HCC: how much iron is too much?

21 January 2018

1 reference

12 December 2020

Inherited metabolic disease of the liver

1 reference

12 December 2020

Iron preloading aggravates nutritional steatohepatitis in rats by increasing apoptotic cell death

1 reference

12 December 2020

Induction of ferritin synthesis by oxidative stress. Transcriptional and post-transcriptional regulation by expansion of the "free" iron pool

1 reference

12 December 2020

Ferritin, metabolic syndrome and NAFLD: elective attractions and dangerous liaisons

1 reference

12 December 2020

COLORIMETRIC DETERMINATION OF FREE FATTY ACIDS IN BIOLOGICAL FLUIDS

1 reference

12 December 2020

Effects of iron overload in a rat nutritional model of non-alcoholic fatty liver disease

1 reference

12 December 2020

Differential effects of fat and sucrose on the development of obesity and diabetes in C57BL/6J and A/J mice

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0066570

Identifiers

DOI

1 reference

4 August 2017

0 references

1 reference

4 August 2017

1 reference