Activation of the androgen receptor by intratumoral bioconversion of androstanediol to dihydrotestosterone in prostate cancer (Q34786897)

4 August 2017

title

Activation of the androgen receptor by intratumoral bioconversion of androstanediol to dihydrotestosterone in prostate cancer (English)

1 reference

4 August 2017

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James L Mohler

1

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4 August 2017

Mark A Titus

2

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4 August 2017

Suxia Bai

3

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4 August 2017

Brian J Kennerley

4

1 reference

4 August 2017

Fred B Lih

5

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4 August 2017

Kenneth B Tomer

6

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4 August 2017

Elizabeth M Wilson

7

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4 August 2017

language of work or name

English

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publication date

8 February 2011

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4 August 2017

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4 August 2017

volume

71

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4 August 2017

issue

4

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4 August 2017

page(s)

1486-1496

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Atmospheric pressure photoionization tandem mass spectrometry of androgens in prostate cancer

4 August 2017

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Prostate cancer stromal cells and LNCaP cells coordinately activate the androgen receptor through synthesis of testosterone and dihydrotestosterone from dehydroepiandrosterone

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Further characterization of human microsomal 3alpha-hydroxysteroid dehydrogenase

8 July 2018

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Amplification and overexpression of androgen receptor gene in hormone-refractory prostate cancer

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Transcript profiling of the androgen signal in normal prostate, benign prostatic hyperplasia, and prostate cancer.

26 October 2018

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Role of the alternate pathway of dihydrotestosterone formation in virilization of the Wolffian ducts of the tammar wallaby, Macropus eugenii

26 October 2018

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26 October 2018

1 reference

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Identification of the major oxidative 3alpha-hydroxysteroid dehydrogenase in human prostate that converts 5alpha-androstane-3alpha,17beta-diol to 5alpha-dihydrotestosterone: a potential therapeutic target for androgen-dependent disease

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3075600

Steroid 5alpha-reductase isozymes I and II in recurrent prostate cancer

26 October 2018

1 reference

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Broadened ligand responsiveness of androgen receptor mutants obtained by random amino acid substitution of H874 and mutation hot spot T877 in prostate cancer.

26 October 2018

1 reference

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Disruption of androgen receptor function inhibits proliferation of androgen-refractory prostate cancer cells.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3075600

A mechanism for androgen receptor-mediated prostate cancer recurrence after androgen deprivation therapy

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3075600

Kinetic analysis of androstenedione 5 alpha-reductase in epithelium and stroma of human prostate

26 October 2018

1 reference

12 December 2020

Intraprostatic androgens and androgen-regulated gene expression persist after testosterone suppression: therapeutic implications for castration-resistant prostate cancer

1 reference

12 December 2020

Elucidation of a complete kinetic mechanism for a mammalian hydroxysteroid dehydrogenase (HSD) and identification of all enzyme forms on the reaction coordinate: the example of rat liver 3alpha-HSD (AKR1C9)

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12 December 2020

3 Alpha-hydroxysteroid oxidoreductase activities in dihydrotestosterone degradation and back-formation in rat prostate and epididymis

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12 December 2020

Dehydroepiandrosterone activates mutant androgen receptors expressed in the androgen-dependent human prostate cancer xenograft CWR22 and LNCaP cells

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12 December 2020

Comparison of prostatic cancer tissue dihydrotestosterone levels at the time of relapse following orchiectomy or estrogen therapy

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12 December 2020

Simultaneous determination of testosterone, dihydrotestosterone and 5 alpha-androstan-3 alpha,-17 beta-diol by isotopic dilution mass spectrometry in plasma and prostatic tissue of patients affected by benign prostatic hyperplasia. Effects of 3-mont

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12 December 2020

Expression and regulation of steroid 5 alpha-reductase 2 in prostate disease

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12 December 2020

10.1158/0008-5472.CAN-10-1343

Identifiers

DOI

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4 August 2017

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4 August 2017

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