Hepatic deficiency of low density lipoprotein receptor-related protein-1 reduces high density lipoprotein secretion and plasma levels in mice (Q34787076)

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English	Hepatic deficiency of low density lipoprotein receptor-related protein-1 reduces high density lipoprotein secretion and plasma levels in mice	scientific article

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23 January 2020

Hepatic deficiency of low density lipoprotein receptor-related protein-1 reduces high density lipoprotein secretion and plasma levels in mice (English)

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23 January 2020

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William S Davidson

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23 January 2020

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Joshua E Basford

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23 January 2020

Lauren Wancata

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23 January 2020

Susanna M Hofmann

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23 January 2020

R A Gangani D Silva

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23 January 2020

Philip N Howles

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23 January 2020

David Y Hui

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23 January 2020

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22 February 2011

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23 January 2020

Journal of Biological Chemistry

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23 January 2020

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23 January 2020

15

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23 January 2020

13079-13087

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23 January 2020

Pro-cathepsin D interacts with the extracellular domain of the beta chain of LRP1 and promotes LRP1-dependent fibroblast outgrowth.

1 reference

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Low density lipoprotein receptor-related protein 1 promotes anti-apoptotic signaling in neurons by activating Akt survival pathway

1 reference

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LRP1 controls cPLA2 phosphorylation, ABCA1 expression and cellular cholesterol export

1 reference

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Loss-of-function variants in endothelial lipase are a cause of elevated HDL cholesterol in humans

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LRP1 controls intracellular cholesterol storage and fatty acid synthesis through modulation of Wnt signaling

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Cathepsin D, a lysosomal protease, regulates ABCA1-mediated lipid efflux

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Targeted inactivation of hepatic Abca1 causes profound hypoalphalipoproteinemia and kidney hypercatabolism of apoA-I

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Neuronal LRP1 functionally associates with postsynaptic proteins and is required for normal motor function in mice.

1 reference

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Purified recombinant human prosaposin forms oligomers that bind procathepsin D and affect its autoactivation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3075654

8 July 2018

The role of endothelial lipase in high-density lipoprotein metabolism

1 reference

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8 July 2018

A novel efflux-recapture process underlies the mechanism of high-density lipoprotein cholesteryl ester-selective uptake mediated by the low-density lipoprotein receptor-related protein

1 reference

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Endocytosis of hepatic lipase and lipoprotein lipase into rat liver hepatocytes in vivo is mediated by the low density lipoprotein receptor-related protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3075654

8 July 2018

Low density lipoprotein receptor-related protein is a calreticulin coreceptor that signals focal adhesion disassembly

1 reference

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8 July 2018

LRP: role in vascular wall integrity and protection from atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3075654

8 July 2018

Inhibition of endothelial lipase causes increased HDL cholesterol levels in vivo

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8 July 2018

Diverse roles for the LDL receptor family

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8 July 2018

Interaction of lecithin:cholesterol acyltransferase (LCAT).alpha 2-macroglobulin complex with low density lipoprotein receptor-related protein (LRP). Evidence for an alpha 2-macroglobulin/LRP receptor-mediated system participating in LCAT clearance

1 reference

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1 reference

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Cellular uptake of saposin (SAP) precursor and lysosomal delivery by the low density lipoprotein receptor-related protein (LRP).

1 reference

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Low density lipoprotein receptor-related protein mediates uptake of cholesteryl esters derived from apoprotein E-enriched lipoproteins

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1 reference

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Thrombospondin signaling through the calreticulin/LDL receptor-related protein co-complex stimulates random and directed cell migration

1 reference

https://pubmed.ncbi.nlm.nih.gov/21343303

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based on heuristic

inferred from PubMed ID database lookup

Mild dyslipidemia in mice following targeted inactivation of the hepatic lipase gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/21343303

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inferred from PubMed ID database lookup

Roles for mannose-6-phosphate receptors in lysosomal enzyme sorting, IGF-II binding and clathrin-coat assembly

1 reference

https://pubmed.ncbi.nlm.nih.gov/21343303

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inferred from PubMed ID database lookup

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10.1074/JBC.M111.229369

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Europe PubMed Central

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23 January 2020

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23 January 2020

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23 January 2020

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