Protection of Cftr knockout mice from acute lung infection by a helper-dependent adenoviral vector expressing Cftr in airway epithelia (Q34787537)

4 August 2017

title

Protection of Cftr knockout mice from acute lung infection by a helper-dependent adenoviral vector expressing Cftr in airway epithelia (English)

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4 August 2017

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David R Koehler

1

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4 August 2017

Umadevi Sajjan

2

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4 August 2017

Yu-Hua Chow

3

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4 August 2017

Bernard Martin

4

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4 August 2017

Geraldine Kent

5

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4 August 2017

A Keith Tanswell

6

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4 August 2017

Colin McKerlie

7

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4 August 2017

Janet F Forstner

8

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4 August 2017

Jim Hu

9

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4 August 2017

language of work or name

English

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publication date

12 December 2003

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Proceedings of the National Academy of Sciences of the United States of America

4 August 2017

published in

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4 August 2017

volume

100

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4 August 2017

issue

26

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4 August 2017

page(s)

15364-15369

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Hypersusceptibility of cystic fibrosis mice to chronic Pseudomonas aeruginosa oropharyngeal colonization and lung infection

4 August 2017

cites work

1 reference

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Preparation of helper-dependent adenoviral vectors

8 July 2018

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Lifetime correction of genetic deficiency in mice with a single injection of helper-dependent adenoviral vector

8 July 2018

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Aerosol and lobar administration of a recombinant adenovirus to individuals with cystic fibrosis. I. Methods, safety, and clinical implications

8 July 2018

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Challenges and strategies for cystic fibrosis lung gene therapy

8 July 2018

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Enhanced susceptibility to pulmonary infection with Burkholderia cepacia in Cftr(-/-) mice

8 July 2018

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A human epithelium-specific vector optimized in rat pneumocytes for lung gene therapy

8 July 2018

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Gene therapy for lung disease: hype or hope?

8 July 2018

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Readministration of adenovirus vector in nonhuman primate lungs by blockade of CD40-CD40 ligand interactions

8 July 2018

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8 July 2018

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Optimization of the helper-dependent adenovirus system for production and potency in vivo

8 July 2018

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Administration of helper-dependent adenoviral vectors and sequential delivery of different vector serotype for long-term liver-directed gene transfer in baboons

8 July 2018

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Status of gene therapy for cystic fibrosis lung disease

8 July 2018

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Promoter attenuation in gene therapy: interferon-gamma and tumor necrosis factor-alpha inhibit transgene expression

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=307573

Development of an epithelium-specific expression cassette with human DNA regulatory elements for transgene expression in lung airways

8 July 2018

1 reference

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Production and characterization of human 293 cell lines expressing the site-specific recombinase Cre.

8 July 2018

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A demonstration using mouse models that successful gene therapy for cystic fibrosis requires only partial gene correction.

8 July 2018

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Microbial pathogenesis in cystic fibrosis: mucoid Pseudomonas aeruginosa and Burkholderia cepacia

8 July 2018

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Cystic fibrosis airway epithelia fail to kill bacteria because of abnormal airway surface fluid.

8 July 2018

1 reference

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AP-1, ETS, and transcriptional silencers regulate retinoic acid-dependent induction of keratin 18 in embryonic cells

8 July 2018

1 reference

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Inefficient gene transfer by adenovirus vector to cystic fibrosis airway epithelia of mice and humans

8 July 2018

1 reference

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Expression of the cystic fibrosis gene in adult human lung

8 July 2018

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The catalog of human cytokeratins: patterns of expression in normal epithelia, tumors and cultured cells

8 July 2018

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An animal model for cystic fibrosis made by gene targeting

8 July 2018

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In vivo transfer of the human cystic fibrosis transmembrane conductance regulator gene to the airway epithelium

8 July 2018

1 reference

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Efficiency of gene transfer for restoration of normal airway epithelial function in cystic fibrosis

8 July 2018

1 reference

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Targeting transgene expression to airway epithelia and submucosal glands, prominent sites of human CFTR expression

8 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2436478100

Targeting transgene expression for cystic fibrosis gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2436478100

High doses of a helper-dependent adenoviral vector yield supraphysiological levels of alpha1-antitrypsin with negligible toxicity

21 January 2018

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https://api.crossref.org/works/10.1073%2FPNAS.2436478100

Genomic DNA transfer with a high-capacity adenovirus vector results in improved in vivo gene expression and decreased toxicity.

21 January 2018

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Reduced inflammation and improved airway expression using helper-dependent adenoviral vectors with a K18 promoter.

21 January 2018

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Increasing epithelial junction permeability enhances gene transfer to airway epithelia In vivo.

21 January 2018

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EGTA enhancement of adenovirus-mediated gene transfer to mouse tracheal epithelium in vivo

21 January 2018

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PEGylation of adenovirus with retention of infectivity and protection from neutralizing antibody in vitro and in vivo.

21 January 2018

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Bilamellar cationic liposomes protect adenovectors from preexisting humoral immune responses

21 January 2018

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Safety and efficacy of repetitive adenovirus-mediated transfer of CFTR cDNA to airway epithelia of primates and cotton rats.

21 January 2018

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Characterization of factors involved in modulating persistence of transgene expression from recombinant adenovirus in the mouse lung

21 January 2018

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Role of CFTR in airway disease

21 January 2018

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Physiological basis of cystic fibrosis: a historical perspective

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=307573

Helper-dependent adenoviral vectors

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/14673110

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Lung disease in the cystic fibrosis mouse exposed to bacterial pathogens

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/14673110

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.2436478100

1 reference

release_rbjvgwkjmba7bemm2sraarnrwm

4 August 2017

0 references

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/rbjvgwkjmba7bemm2sraarnrwm

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMC publication ID

307573

1 reference

4 August 2017

1 reference