Mechanisms of stimulation of the immune response by aluminum adjuvants (Q34787679)

4 August 2017

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title

Mechanisms of stimulation of the immune response by aluminum adjuvants (English)

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4 August 2017

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Harm HogenEsch

1

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4 August 2017

language of work or name

English

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publication date

1 May 2002

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4 August 2017

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4 August 2017

volume

20 Suppl 3

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4 August 2017

page(s)

S34-9

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Aluminum compounds used as adjuvants in vaccines

4 August 2017

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On the effect of Al(OH)3 as an immunological adjuvant.

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In vivo induction of type 1 and 2 immune responses against protein antigens

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Some Observations on the Use of Alum Precipitated Diphtheria Toxoid

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Characterization of the MN gp120 HIV-1 vaccine: antigen binding to alum.

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In vivo distribution of radioactivity in mice after injection of biodegradable polymer microspheres containing 14C-labeled tetanus toxoid

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The in vitro displacement of adsorbed model antigens from aluminium-containing adjuvants by interstitial proteins.

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Change in the degree of adsorption of proteins by aluminum-containing adjuvants following exposure to interstitial fluid: freshly prepared and aged model vaccines

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Degree of antigen adsorption in the vaccine or interstitial fluid and its effect on the antibody response in rabbits

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Enhancement of DNA vaccine potency using conventional aluminum adjuvants

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Enhanced type I immune response to a hepatitis B DNA vaccine by formulation with calcium- or aluminum phosphate

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Dendritic cells and the control of immunity

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Toll-like receptors: critical proteins linking innate and acquired immunity

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Toll-like receptors control activation of adaptive immune responses

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The Common vaccine adjuvant aluminum hydroxide up-regulates accessory properties of human monocytes via an interleukin-4-dependent mechanism

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Neither interleukin-6 nor signalling via tumour necrosis factor receptor-1 contribute to the adjuvant activity of Alum and Freund's adjuvant

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Eosinophil Response to Alum Adjuvants: Involvement of T Cells in Non-Antigen-Dependent Mechanisms

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Consequences of cell death: exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells

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Cytokines induce the development of functionally heterogeneous T helper cell subsets

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The expanding universe of T-cell subsets: Th1, Th2 and more.

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IL-12-deficient mice are defective in IFN gamma production and type 1 cytokine responses

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Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity

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Interleukin-12 is produced by dendritic cells and mediates T helper 1 development as well as interferon-gamma production by T helper 1 cells.

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High level IL-12 production by murine dendritic cells: upregulation via MHC class II and CD40 molecules and downregulation by IL-4 and IL-10.

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Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation

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Maturation, activation, and protection of dendritic cells induced by double-stranded RNA

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Mechanism of suppression of cell-mediated immunity by measles virus

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Selective suppression of interleukin-12 induction after macrophage receptor ligation

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7 January 2021

Regulation of interleukin-12 by complement receptor 3 signaling

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Selective suppression of IL-12 production by chemoattractants

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7 January 2021

Control of TH2 polarization by the chemokine monocyte chemoattractant protein-1

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Retrovirally induced switch from production of IL-12 to IL-4 in dendritic cells

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7 January 2021

In interleukin-4-deficient mice, alum not only generates T helper 1 responses equivalent to Freund's complete adjuvant, but continues to induce T helper 2 cytokine production

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7 January 2021

CpG motifs in bacterial DNA trigger direct B-cell activation

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Bacterial DNA and immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells

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Vaccine adjuvants based on gamma inulin.

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7 January 2021

The role of complement and complement receptors in induction and regulation of immunity.

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7 January 2021

C3d of complement as a molecular adjuvant: bridging innate and acquired immunity

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7 January 2021

10.1016/S0264-410X(02)00169-X

Identifiers

DOI

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4 August 2017

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