Highly automated QT measurement techniques in 7 thorough QT studies implemented under ICH E14 guidelines (Q34788845)

4 August 2017

Highly automated QT measurement techniques in 7 thorough QT studies implemented under ICH E14 guidelines (English)

1 reference

4 August 2017

0 references

5

Scott McNitt

1 reference

4 August 2017

8

Wojciech Zareba

1 reference

4 August 2017

Jean-Philippe Couderc

1

1 reference

4 August 2017

Christine Garnett

2

1 reference

4 August 2017

Mike Li

3

1 reference

4 August 2017

Robert Handzel

4

1 reference

4 August 2017

Xiajuan Xia

6

1 reference

4 August 2017

Slava Polonsky

7

1 reference

4 August 2017

1 January 2011

1 reference

Annals of Noninvasive Electrocardiology

4 August 2017

1 reference

4 August 2017

16

1 reference

4 August 2017

1

1 reference

4 August 2017

13-24

1 reference

The effect of moxifloxacin on QTc and implications for the design of thorough QT studies

4 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076006

Methodology of QT-interval measurement in the modular ECG analysis system (MEANS).

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076006

PC-Based ECG waveform recognition-validation of novel software against a reference ECG database.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076006

Baseline values and sotalol-induced changes of ventricular repolarization duration, heterogeneity, and instability in patients with a history of drug-induced torsades de pointes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076006

Automatic analysis of cardiac repolarization morphology using Gaussian mesa function modeling.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076006

Effect of single doses of maraviroc on the QT/QTc interval in healthy subjects

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076006

Concentration-QT relationships play a key role in the evaluation of proarrhythmic risk during regulatory review.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076006

Analyses of dynamic beat-to-beat QT-TQ interval (ECG restitution) changes in humans under normal sinus rhythm and prior to an event of torsades de pointes during QT prolongation caused by sotalol.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076006

Impaired T-amplitude adaptation to heart rate characterizes I(Kr) inhibition in the congenital and acquired forms of the long QT syndrome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076006

Precision of QT interval measurement by advanced electrocardiographic equipment

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076006

QT prolongation and proarrhythmia by moxifloxacin: concordance of preclinical models in relation to clinical outcome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076006

Evaluation of vardenafil and sildenafil on cardiac repolarization

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076006

Drug-induced prolongation of the QT interval

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076006

Measuring agreement in method comparison studies

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076006

QT interval analysis on ambulatory electrocardiogram recordings: a selective beat averaging approach

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076006

Gender and the relationship between ventricular repolarization and cardiac cycle length during 24-h Holter recordings.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076006

Accuracy of four automatic QT measurement techniques in cardiac patients and healthy subjects

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076006

Comparison of automatic QT measurement techniques in the normal 12 lead electrocardiogram

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076006

Effect of brivaracetam on cardiac repolarisation--a thorough QT study

8 July 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1542-474X.2010.00402.X

Raltegravir thorough QT/QTc study: a single supratherapeutic dose of raltegravir does not prolong the QTcF interval

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1542-474X.2010.00402.X

Effect of levetiracetam on cardiac repolarization in healthy subjects: a single-dose, randomized, placebo- and active-controlled, four-way crossover study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1542-474X.2010.00402.X

Randomized, double-blind, crossover study to investigate the effect of rivaroxaban on QT-interval prolongation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1542-474X.2010.00402.X

Effects of three fluoroquinolones on QT interval in healthy adults after single doses

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1542-474X.2010.00402.X

Improving the detection of subtle I(Kr)-inhibition: assessing electrocardiographic abnormalities of repolarization induced by moxifloxacin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1542-474X.2010.00402.X

Performance assessment of standard algorithms for dynamic R-T interval measurement: comparison between R-Tapex and R-T(end) approach.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1542-474X.2010.00402.X

Man versus machine: is there an optimal method for QT measurements in thorough QT studies?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1542-474X.2010.00402.X

Philips QT interval measurement algorithms for diagnostic, ambulatory, and patient monitoring ECG applications.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1542-474X.2010.00402.X

Automated QT measurement and application to detection of moxifloxacin-induced changes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1542-474X.2010.00402.X

Automated QT analysis that learns from cardiologist annotations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1542-474X.2010.00402.X

Robust QT interval estimation--from algorithm to validation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1542-474X.2010.00402.X

Problems of heart rate correction in assessment of drug-induced QT interval prolongation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1542-474X.2010.00402.X

The imprecision in heart rate correction may lead to artificial observations of drug induced QT interval changes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1542-474X.2010.00402.X

Levocetirizine does not prolong the QT/QTc interval in healthy subjects: results from a thorough QT study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1542-474X.2010.00402.X

New descriptors of T-wave morphology are independent of heart rate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1542-474X.2010.00402.X

Moxifloxacin-induced torsades de pointes.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076006

Beat-to-beat Adaptation of QT Interval to Heart Rate.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076006

An update on QT measurement and interpretation methodologies

26 October 2018

1 reference

12 December 2020

Dynamic coupling between heart rate and ventricular repolarisation

1 reference

12 December 2020

The measurement of the Q-T interval of the electrocardiogram

1 reference

12 December 2020

Moxifloxacin and torsade de pointes

1 reference

12 December 2020

Thorough QT study with recommended and supratherapeutic doses of tolterodine

1 reference

12 December 2020

QT interval: how to measure it and what is "normal"

1 reference

12 December 2020

10.1111/J.1542-474X.2010.00402.X

Identifiers

DOI

1 reference

4 August 2017

1 reference

4 August 2017

1 reference