Location of the CD8 T cell epitope within the antigenic precursor determines immunogenicity and protection against the Toxoplasma gondii parasite. (Q34789311)

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English	Location of the CD8 T cell epitope within the antigenic precursor determines immunogenicity and protection against the Toxoplasma gondii parasite.	scientific article

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4 March 2020

Location of the CD8 T cell epitope within the antigenic precursor determines immunogenicity and protection against the Toxoplasma gondii parasite (English)

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4 March 2020

Toxoplasma gondii

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4 March 2020

Nicolas Blanchard

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Virginie Feliu

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4 March 2020

Virginie Vasseur

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4 March 2020

Harshita S Grover

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4 March 2020

H Hamlet Chu

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Mark J Brown

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4 March 2020

Jeremy Wang

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4 March 2020

Ellen A Robey

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4 March 2020

Nilabh Shastri

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20 June 2013

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4 March 2020

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4 March 2020

9

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4 March 2020

e1003449

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4 March 2020

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4 March 2020

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Creative Commons Attribution 4.0 International

20 June 2013

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Positional bias of MHC class I restricted T-cell epitopes in viral antigens is likely due to a bias in conservation

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Phosphorylation of immunity-related GTPases by a Toxoplasma gondii-secreted kinase promotes macrophage survival and virulence

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Topological journey of parasite-derived antigens for presentation by MHC class I molecules

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Primary CTL response magnitude in mice is determined by the extent of naive T cell recruitment and subsequent clonal expansion

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Differential regulation of effector- and central-memory responses to Toxoplasma gondii Infection by IL-12 revealed by tracking of Tgd057-specific CD8+ T cells

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Endoplasmic reticulum aminopeptidase associated with antigen processing defines the composition and structure of MHC class I peptide repertoire in normal and virus-infected cells

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8 July 2018

Dynamic Imaging of CD8(+) T cells and dendritic cells during infection with Toxoplasma gondii

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8 July 2018

Selection of polymorphic peptides from GRA6 and GRA7 sequences of Toxoplasma gondii strains to be used in serotyping

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8 July 2018

The amino acid sequences flanking an antigenic determinant can strongly affect MHC class I cross-presentation without altering direct presentation

1 reference

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8 July 2018

Host ER-parasitophorous vacuole interaction provides a route of entry for antigen cross-presentation in Toxoplasma gondii-infected dendritic cells

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8 July 2018

Parasite stage-specific recognition of endogenous Toxoplasma gondii-derived CD8+ T cell epitopes

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8 July 2018

Naive precursor frequencies and MHC binding rather than the degree of epitope diversity shape CD8+ T cell immunodominance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3688528

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Endogenous naive CD8+ T cell precursor frequency regulates primary and memory responses to infection

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Portable flanking sequences modulate CTL epitope processing

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Presentation of Toxoplasma gondii antigens via the endogenous major histocompatibility complex class I pathway in nonprofessional and professional antigen-presenting cells

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Naive CD4(+) T cell frequency varies for different epitopes and predicts repertoire diversity and response magnitude.

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1 reference

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8 July 2018

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1003449

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Presentation of endogenous peptide/MHC class I complexes is profoundly influenced by specific C-terminal flanking residues.

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1 reference

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21 January 2018

Sequences that flank subdominant and cryptic epitopes influence the proteolytic generation of MHC class I-presented peptides

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro correlates of Ld-restricted resistance to toxoplasmic encephalitis and their critical dependence on parasite strain

1 reference

https://pubmed.ncbi.nlm.nih.gov/23818852

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential membrane targeting of the secretory proteins GRA4 and GRA6 within the parasitophorous vacuole formed by Toxoplasma gondii

1 reference

https://pubmed.ncbi.nlm.nih.gov/23818852

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Post-translational membrane sorting of the Toxoplasma gondii GRA6 protein into the parasite-containing vacuole is driven by its N-terminal domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/23818852

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1371/JOURNAL.PPAT.1003449

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4 March 2020

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4 March 2020

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4 March 2020

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