Uncertainties - discrepancies in immunology (Q34792441)

4 August 2017

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title

Uncertainties - discrepancies in immunology (English)

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4 August 2017

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Rolf M Zinkernagel

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4 August 2017

1 July 2002

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4 August 2017

Immunological Reviews

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4 August 2017

185

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4 August 2017

103-125

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Immunology taught by viruses

4 August 2017

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https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Potential strategies utilised by papillomavirus to evade host immunity

21 January 2018

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https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

21 January 2018

On immunological memory

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https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Maternal antibodies, childhood infections, and autoimmune diseases

21 January 2018

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https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

History of immunology: development of the concept of immunologic specificity: II.

21 January 2018

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https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

A QUANTITATIVE STUDY OF THE PRECIPITIN REACTION BETWEEN TYPE III PNEUMOCOCCUS POLYSACCHARIDE AND PURIFIED HOMOLOGOUS ANTIBODY.

21 January 2018

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https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice

21 January 2018

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https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

B cell repertoire in adult antigen-free and conventional neonatal BALB/c mice. I. Preferential utilization of the CH-proximal VH gene family PC7183.

21 January 2018

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https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

On the role of antigen in maintaining cytotoxic T-cell memory

21 January 2018

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https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

A comparison of T cell memory against the same antigen induced by virus versus intracellular bacteria.

21 January 2018

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https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Ligand recognition by alpha beta T cell receptors

21 January 2018

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https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Specific low-affinity recognition of major histocompatibility complex plus peptide by soluble T-cell receptor

21 January 2018

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https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Selective expansion of high- or low-avidity cytotoxic T lymphocytes and efficacy for adoptive immunotherapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

The carrier effect in the secondary response to hapten-protein conjugates. V. Use of antilymphocyte serum to deplete animals of helper cells

21 January 2018

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https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

The requirement of more than one antigenic determinant for immunogenicity

21 January 2018

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https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Primary antibody responses to a well-defined and unique hapten are not enhanced by preimmunization with carrier: analysis in a viral model

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Analysis of the kinetics of antiviral memory T help in vivo: characterization of short-lived cross-reactive T help

21 January 2018

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https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

What is missing in immunology to understand immunity?

21 January 2018

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https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Early high-affinity neutralizing anti-viral IgG responses without further overall improvements of affinity

21 January 2018

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https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Poliovirus vaccine vectors elicit antigen-specific cytotoxic T cells and protect mice against lethal challenge with malignant melanoma cells expressing a model antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Cytotoxic T-cell immunity to virus-infected non-haematopoietic cells requires presentation of exogenous antigen

21 January 2018

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https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

The role of antibody concentration and avidity in antiviral protection.

21 January 2018

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https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

The role of somatic mutation in the generation of the protective humoral immune response against vesicular stomatitis virus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Virus neutralization by germ-line vs. hypermutated antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

The relationship between antigenic structure and the requirement for thymus-derived cells in the immune response

21 January 2018

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https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Antigens as Immunoregulators

21 January 2018

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https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Autoantibody production in hepatitis B e antigen transgenic mice elicited with a self T-cell peptide and inhibited with nonself peptides

21 January 2018

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https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Antigenic variation in malaria

21 January 2018

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https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Analyses of the cytotoxic T lymphocyte responses to glycoprotein and nucleoprotein components of lymphocytic choriomeningitis virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Major histocompatibility complex--dependent T cell epitopes of lymphocytic choriomeningitis virus nucleoprotein and their protective capacity against viral disease

21 January 2018

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https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Hypothesis: why do so many lymphocytes respond to major histocompatibility antigens?

21 January 2018

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https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

A critical role of natural immunoglobulin M in immediate defense against systemic bacterial infection

21 January 2018

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https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

IgA production without mu or delta chain expression in developing B cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Protective long-term antibody memory by antigen-driven and T help-dependent differentiation of long-lived memory B cells to short-lived plasma cells independent of secondary lymphoid organs

21 January 2018

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https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Control of T-cell development by the pre-T and alpha beta T-cell receptor

21 January 2018

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https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

21 January 2018

Why positive selection?

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https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

T and B cell tolerance and responses to viral antigens in transgenic mice: implications for the pathogenesis of autoimmune versus immunopathological disease

21 January 2018

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https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Antigen-presenting cell types

21 January 2018

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https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

A Theory of Self-Nonself Discrimination: Paralysis and induction involve the recognition of one and two determinants on an antigen, respectively

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Costimulation of T lymphocytes: the role of CD28, CTLA-4, and B7/BB1 in interleukin-2 production and immunotherapy

21 January 2018

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https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

The induction of tolerance by dendritic cells that have captured apoptotic cells

21 January 2018

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https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Fibroblasts as efficient antigen-presenting cells in lymphoid organs

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Immune surveillance against a solid tumor fails because of immunological ignorance

21 January 2018

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https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Antigen presentation to CD8+ T cells: cross-priming in infectious diseases.

21 January 2018

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https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Cross-presentation: a general mechanism for CTL immunity and tolerance

21 January 2018

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https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs

21 January 2018

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https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Induction of protective cytotoxic T cells with viral proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Critical role for activation of antigen-presenting cells in priming of cytotoxic T cell responses after vaccination with virus-like particles

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Constitutive class I-restricted exogenous presentation of self antigens in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Ablation of "tolerance" and induction of diabetes by virus infection in viral antigen transgenic mice

21 January 2018

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https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

The somatic generation of immune recognition

21 January 2018

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https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Role of bone marrow-derived cells in presenting MHC class I-restricted tumor antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Consequences of cell death: exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

The protecton: the unit of humoral immunity selected by evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

IgG2a restriction of murine antibodies elicited by viral infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Protection against immunopathological consequences of a viral infection by activated but not resting cytotoxic T cells: T cell memory without "memory T cells"?

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Virus-triggered acquired immunodeficiency by cytotoxic T-cell-dependent destruction of antigen-presenting cells and lymph follicle structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Crucial role of marginal zone macrophages and marginal zone metallophils in the clearance of lymphocytic choriomeningitis virus infection

21 January 2018

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https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Human Peyer's patches: lympho-epithelial relationships and characteristics of immunoglobulin-producing cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Naive and memory T cells show distinct pathways of lymphocyte recirculation

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Cytotoxic T-cell memory without antigen

21 January 2018

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https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Virus-specific CD8+ T-cell memory determined by clonal burst size

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Immunological memory and protective immunity: understanding their relation

21 January 2018

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https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Looking out for memory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Attrition of T cell memory: selective loss of LCMV epitope-specific memory CD8 T cells following infections with heterologous viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Persistence of memory CD8 T cells in MHC class I-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Dynamics of T lymphocyte responses: intermediates, effectors, and memory cells

21 January 2018

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https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

On T cell memory: arguments for antigen dependence

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Humoral immunity due to long-lived plasma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Lifetime of plasma cells in the bone marrow.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

THE IMMUNOLOGICAL BASIS OF ACQUIRED CELLULAR RESISTANCE

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

The influence of immunologically committed lymphoid cells on macrophage activity in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

The relationship of delayed hypersensitivity to acquired cellular resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Skin test to assess virus-specific cytotoxic T-cell activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Resistance to intracellular infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

The hepatitis B virus persists for decades after patients' recovery from acute viral hepatitis despite active maintenance of a cytotoxic T-lymphocyte response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Persistence of lymphocytic choriomeningitis virus at very low levels in immune mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Selection of genetic variants of lymphocytic choriomeningitis virus in spleens of persistently infected mice. Role in suppression of cytotoxic T lymphocyte response and viral persistence

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

The biology of lymphocytic choriomeningitis infection: virus-induced immune disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

21 January 2018

Vaccination for Disease

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https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Virus persistence in acutely infected immunocompetent mice by exhaustion of antiviral cytotoxic effector T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

The Influence of Thymus H-2 Antigens on the Specificity of Maturing Killer and Helper Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Thymus and Lymphohemopoietic Cells: Their Role in T Cell Maturation in Selection of T Cells' H-2-Restriction-Specificity and in H-2 Linked Ir Gene Control

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Role of H-2 Gene Products in the Function of T Helper Cells from Normal and Chimeric Mice in Vivo1

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

In a fully H-2 incompatible chimera, T cells of donor origin can respond to minor histocompatibility antigens in association with either donor or host H-2 type

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Restriction specificities, alloreactivity, and allotolerance expressed by T cells from nude mice reconstituted with H-2-compatible or -incompatible thymus grafts

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

On the role of thymic epithelium vs. bone marrow-derived cells in repertoire selection of T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Mechanisms in the suppression of delayed hypersensitivity in the guinea pig by 6-mercaptopurine. II: Kinetic and morphologic studies on the monocyte-macrophage component

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

The standard model of T-cell receptor function: a critical reassessment

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

A critical role for neutralizing-antibody-producing B cells, CD4(+) T cells, and interferons in persistent and acute infections of mice with lymphocytic choriomeningitis virus: implications for adoptive immunotherapy of virus carriers

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Cell migration, chimerism, and graft acceptance

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Peripheral clonal deletion of antiviral memory CD8+ T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

A minimal model for the self-nonself discrimination: a return to the basics

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Dendritic cells induce autoimmune diabetes and maintain disease via de novo formation of local lymphoid tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

How the immune system works to protect the host from infection: a personal view

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Somatic mutation and the maturation of immune response to 2-phenyl oxazolone

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Roles of tumour localization, second signals and cross priming in cytotoxic T-cell induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

T-cell specificity for H–2 and Ir gene phenotype correlates with the phenotype of thymic antigen-presenting cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

Development of the concept of immunologic specificity: III

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

7 January 2021

Immune response in mice that lack the interferon-gamma receptor

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

7 January 2021

Control of early viral and bacterial distribution and disease by natural antibodies

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

7 January 2021

Kinetics and affinity of reactions between an antigen-specific T cell receptor and peptide-MHC complexes

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

7 January 2021

T cell receptor-MHC class I peptide interactions: affinity, kinetics, and specificity

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

7 January 2021

Cytotoxic T lymphocytes specific for influenza virus.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

7 January 2021

Mechanisms of exogenous antigen presentation by MHC class I molecules in vitro and in vivo: implications for generating CD8+ T cell responses to infectious agents, tumors, transplants, and vaccines

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

7 January 2021

Paralytic Poliomyelitis: Old Dogmas and New Perspectives

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

7 January 2021

The influence of antigen organization on B cell responsiveness

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

7 January 2021

Assembly of MHC class I molecules analyzed in vitro

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

7 January 2021

N protein is the predominant antigen recognized by vesicular stomatitis virus-specific cytotoxic T cells

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

7 January 2021

Positive and negative selection of T lymphocytes

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

7 January 2021

A primitive T cell-independent mechanism of intestinal mucosal IgA responses to commensal bacteria

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

7 January 2021

The regulatory influence of activated T cells on B cell responses to antigen

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

7 January 2021

A new analysis of allogeneic interactions

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

7 January 2021

The CD8 response on autopilot.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

7 January 2021

Correlation of T cell independence of antibody responses with antigen dose reaching secondary lymphoid organs: implications for splenectomized patients and vaccine design

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

7 January 2021

Memory T cells don't need practice

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

7 January 2021

The generation and maintenance of memory T and B cells

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

7 January 2021

Antiviral protection by vesicular stomatitis virus-specific antibodies in alpha/beta interferon receptor-deficient mice.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

7 January 2021

Bone marrow is a major site of long-term antibody production after acute viral infection

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

7 January 2021

The immunopathogenesis of HIV infection

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

7 January 2021

On immunological memory

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

7 January 2021

Immunity to infection

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

7 January 2021

The homograft reaction

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

7 January 2021

Self-nonself discrimination revisited. Introduction

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18511.X

7 January 2021

10.1034/J.1600-065X.2002.18511.X

Identifiers

DOI

1 reference

4 August 2017

1 reference

PubMed ID

12190926