Antitumor efficacy of cytotoxic drugs and the monoclonal antibody 806 is enhanced by the EGF receptor inhibitor AG1478. (Q34792693)

4 August 2017

title

Antitumor efficacy of cytotoxic drugs and the monoclonal antibody 806 is enhanced by the EGF receptor inhibitor AG1478. (English)

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4 August 2017

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Rodney B Luwor

2

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Terrance G Johns

object named as

Terrance G Johns

1

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Lloyd J. Old

10

object named as

Lloyd J Old

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4 August 2017

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Elisabeth Stockert

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4 August 2017

Carmel Murone

3

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4 August 2017

Francesca Walker

4

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4 August 2017

Janet Weinstock

5

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4 August 2017

Angela A Vitali

6

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4 August 2017

Rushika M Perera

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4 August 2017

Achim A Jungbluth

8

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4 August 2017

Edouard C Nice

11

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4 August 2017

Antony W Burgess

12

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4 August 2017

Andrew M Scott

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4 August 2017

language of work or name

English

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publication date

15 December 2003

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Proceedings of the National Academy of Sciences of the United States of America

4 August 2017

published in

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4 August 2017

volume

100

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4 August 2017

issue

26

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4 August 2017

page(s)

15871-15876

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A monoclonal antibody recognizing human cancers with amplification/overexpression of the human epidermal growth factor receptor

4 August 2017

cites work

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Growth suppression of intracranial xenografted glioblastomas overexpressing mutant epidermal growth factor receptors by systemic administration of monoclonal antibody (mAb) 806, a novel monoclonal antibody directed to the receptor.

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Tyrphostin AG 1478 preferentially inhibits human glioma cells expressing truncated rather than wild-type epidermal growth factor receptors

8 July 2018

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Human glioblastoma xenografts overexpressing a tumor-specific mutant epidermal growth factor receptor sensitized to cisplatin by the AG1478 tyrosine kinase inhibitor

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Unliganded Epidermal Growth Factor Receptor Dimerization Induced by Direct Interaction of Quinazolines with the ATP Binding Site

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Brain tumors in mice are susceptible to blockade of epidermal growth factor receptor (EGFR) with the oral, specific, EGFR-tyrosine kinase inhibitor ZD1839 (iressa).

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High-performance liquid chromatographic analysis of the tyrphostin AG1478, a specific inhibitor of the epidermal growth factor receptor tyrosine kinase, in mouse plasma.

26 October 2018

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Antitumor effect and potentiation of cytotoxic drugs activity in human cancer cells by ZD-1839 (Iressa), an epidermal growth factor receptor-selective tyrosine kinase inhibitor

26 October 2018

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Monoclonal antibodies to target epidermal growth factor receptor-positive tumors: a new paradigm for cancer therapy

26 October 2018

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Ratiometric assay of epidermal growth factor receptor tyrosine kinase activation

21 January 2018

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Sustained loss of a neoplastic phenotype by brief inactivation of MYC

21 January 2018

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PD153035, a tyrosine kinase inhibitor, prevents epidermal growth factor receptor activation and inhibits growth of cancer cells in a receptor number-dependent manner

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/14676326

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Efficacy of cytotoxic agents against human tumor xenografts is markedly enhanced by coadministration of ZD1839 (Iressa), an inhibitor of EGFR tyrosine kinase

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/14676326

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Quantitative analysis of the EGF receptor autocrine system reveals cryptic regulation of cell response by ligand capture

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/14676326

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.2036503100

1 reference

4 August 2017

0 references

1 reference

4 August 2017

1 reference