Dopamine D4 receptor involvement in the discriminative stimulus effects in rats of LSD, but not the phenethylamine hallucinogen DOI. (Q34792844)

4 August 2017

Dopamine D4 receptor involvement in the discriminative stimulus effects in rats of LSD, but not the phenethylamine hallucinogen DOI. (English)

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lysergic acid diethylamide

4 August 2017

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inferred from title

author name string

Danuta Marona-Lewicka

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1

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4 August 2017

Benjamin R Chemel

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2

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4 August 2017

David E Nichols

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3

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4 August 2017

6 July 2008

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4 August 2017

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4 August 2017

203

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4 August 2017

2

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4 August 2017

265-277

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https://scigraph.springernature.com/pub.10.1007/s00213-008-1238-0

4 August 2017

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Discriminative stimulus properties of the serotonergic agent 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI).

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Serotonergic receptor subtypes and hallucinogen-induced stimulus control

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Evidence for the preferential involvement of 5-HT2A serotonin receptors in stress- and drug-induced dopamine release in the rat medial prefrontal cortex

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Evidence for 5-HT2 involvement in the mechanism of action of hallucinogenic agents

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Human D2 and D4 dopamine receptors couple through betagamma G-protein subunits to inwardly rectifying K+ channels (GIRK1) in a Xenopus oocyte expression system: selective antagonism by L-741,626 and L-745,870 respectively.

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12 December 2020

Further evidence that the delayed temporal dopaminergic effects of LSD are mediated by a mechanism different than the first temporal phase of action.

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Cellular localization of serotonin(2A) (5HT(2A)) receptors in the rat brain

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Short- and long-term heterologous sensitization of adenylate cyclase by D4 dopamine receptors

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D4 dopamine receptor binding affinity does not distinguish between typical and atypical antipsychotic drugs

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The 5-HT1A receptor and the stimulus effects of LSD in the rat.

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12 December 2020

Mechanism of tolerance development to 2,5-dimethoxy-4-iodoamphetamine in rats: down-regulation of the 5-HT2A, but not 5-HT2C, receptor.

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Role of striatal serotonin2A and serotonin2C receptor subtypes in the control of in vivo dopamine outflow in the rat striatum

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Bidirectional regulation of Ca2+/calmodulin-dependent protein kinase II activity by dopamine D4 receptors in prefrontal cortex

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Dopamine D4 receptors modulate GABAergic signaling in pyramidal neurons of prefrontal cortex.

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The prefrontal cortex--an update: time is of the essence

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5-HT2A/2C receptor agonists potentiate the discriminative cue of (+)-amphetamine in the rat

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Pharmacologic mechanisms of serotonergic regulation of dopamine neurotransmission

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Regulation of NMDA Receptors by Dopamine D4Signaling in Prefrontal Cortex

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LSD and structural analogs: pharmacological evaluation at D1 dopamine receptors

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Behavioral effects of the highly selective serotonin releasing agent 5-methoxy-6-methyl-2-aminoindan

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WAY-100635 is a potent dopamine D4 receptor agonist

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Bidirectional dopamine modulation of GABAergic inhibition in prefrontal cortical pyramidal neurons.

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Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine

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Electrophysiological, biochemical, neurohormonal and behavioural studies with WAY-100635, a potent, selective and silent 5-HT1A receptor antagonist

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2-[4-(3,4-Dimethylphenyl)piperazin-1-ylmethyl]-1H benzoimidazole (A-381393), a selective dopamine D4 receptor antagonist

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Activation of 5-HT2A/2C receptors within the nucleus accumbens increases local dopaminergic transmission.

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M100,907, a selective 5-HT(2A) antagonist, attenuates dopamine release in the rat medial prefrontal cortex

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Local infusion of the serotonin antagonists ritanserin or ICS 205,930 increases in vivo dopamine release in the rat medial prefrontal cortex.

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Co-localization of 5-HT 2A -receptor- and GABA-immunoreactivity in neurones in the periaqueductal grey matter of the rat.

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DOI, a 5-HT2A/2C receptor agonist, potentiates amphetamine-induced dopamine release in rat striatum

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Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

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Sensitization of endogenous and recombinant adenylate cyclase by activation of D2 dopamine receptors.

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Localization of dopamine D4 receptors in GABAergic neurons of the primate brain

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Serotonin model of schizophrenia: emerging role of glutamate mechanisms

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Activation of dopamine D4 receptors induces synaptic translocation of Ca2+/calmodulin-dependent protein kinase II in cultured prefrontal cortical neurons

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5-HT modulation of dopamine release in basal ganglia in psilocybin-induced psychosis in man--a PET study with [11C]raclopride.

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A drug discrimination analysis of lysergic acid diethylamide (LSD): in vivo agonist and antagonist effects of purported 5-hydroxytryptamine antagonists and of pirenperone, a LSD-antagonist.

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Binding of antipsychotic drugs to human brain receptors focus on newer generation compounds

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Ultrastructural localization of serotonin2A receptors in the middle layers of the rat prelimbic prefrontal cortex

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A pharmacological profile of the selective silent 5-HT1A receptor antagonist, WAY-100635

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Distinct temporal phases in the behavioral pharmacology of LSD: dopamine D2 receptor-mediated effects in the rat and implications for psychosis

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Quantitative analysis of glutamatergic and GABAergic neurons expressing 5-HT(2A) receptors in human and monkey prefrontal cortex.

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WAY-100635 has high selectivity for serotonin 5-HT(1A) versus dopamine D(4) receptors.

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Functional activation by central monoamines of human dopamine D(4) receptor polymorphic variants coupled to GIRK channels in Xenopus oocytes.

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Dopamine D4 receptor-deficient mice display cortical hyperexcitability

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Biological profile of L-745,870, a selective antagonist with high affinity for the dopamine D4 receptor

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Synthesis and evaluation of 4-(2'-methoxyphenyl)-1-[2'-[N-(2"-pyridinyl)-p- iodobenzamido]ethyl]piperazine (p-MPPI): a new iodinated 5-HT1A ligand.

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The stimulus effects of 8-OH-DPAT: evidence for a 5-HT2A receptor-mediated component

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The activation of 5-HT receptors in prefrontal cortex enhances dopaminergic activity

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Discovery of 2-(4-pyridin-2-ylpiperazin-1-ylmethyl)-1H-benzimidazole (ABT-724), a dopaminergic agent with a novel mode of action for the potential treatment of erectile dysfunction

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Atypical neuroleptics have low affinity for dopamine D2 receptors or are selective for D4 receptors

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Activation of dopamine D4 receptors by ABT-724 induces penile erection in rats

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[35S]Guanosine-5'-O-(3-thio)triphosphate binding as a measure of efficacy at human recombinant dopamine D4.4 receptors: actions of antiparkinsonian and antipsychotic agents.

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The principal features and mechanisms of dopamine modulation in the prefrontal cortex

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Differential involvement of 5-HT(2A) receptors in the discriminative-stimulus effects of cocaine and methamphetamine

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10.1007/S00213-008-1238-0

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DOI

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Dimensions Publication ID

4 August 2017

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