Neuroprotection by propargylamines in Parkinson's disease: suppression of apoptosis and induction of prosurvival genes (Q34802158)

4 August 2017

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title

Neuroprotection by propargylamines in Parkinson's disease: suppression of apoptosis and induction of prosurvival genes (English)

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4 August 2017

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Wakako Maruyama

1

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4 August 2017

Yukihiro Akao

2

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4 August 2017

Maria Chrisina Carrillo

3

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4 August 2017

Ken-ichi Kitani

4

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4 August 2017

Moussa B H Youdium

5

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4 August 2017

Makoto Naoi

6

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4 August 2017

1 September 2002

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Neurotoxicology and Teratology

4 August 2017

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4 August 2017

24

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4 August 2017

5

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4 August 2017

675-682

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Apoptosis induced by an endogenous neurotoxin, N-methyl(R)salsolinol, is mediated by activation of caspase 3.

4 August 2017

1 reference

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Neuroprotective strategies for basal ganglia degeneration: Parkinson's and Huntington's diseases

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(-)Deprenyl increases activities of superoxide dismutase and catalase in striatum but not in hippocampus: the sex and age-related differences in the optimal dose in the rat

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Enhancing effect of rasagiline on superoxide dismutase and catalase activities in the dopaminergic system in the rat

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An evaluation of the role of mitochondria in neurodegenerative diseases: mitochondrial mutations and oxidative pathology, protective nuclear responses, and cell death in neurodegeneration

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Deprenyl suppresses the oxidant stress associated with increased dopamine turnover

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Tyramine antagonistic properties of AGN 1135, an irreversible inhibitor of monoamine oxidase type B.

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Increased survival of dopaminergic neurons by rasagiline, a monoamine oxidase B inhibitor.

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Inhibition of interleukin 1beta converting enzyme family proteases reduces ischemic and excitotoxic neuronal damage

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7 January 2021

Caspase-3: A vulnerability factor and final effector in apoptotic death of dopaminergic neurons in Parkinson's disease.

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Protection against the dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine by monoamine oxidase inhibitors

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Neuroprotective effect of rasagiline, a selective monoamine oxidase-B inhibitor, against closed head injury in the mouse.

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Glyceraldehyde-3-phosphate dehydrogenase antisense oligodeoxynucleotides protect against cytosine arabinonucleoside-induced apoptosis in cultured cerebellar neurons

1 reference

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7 January 2021

Cell death mechanisms in Parkinson's disease

1 reference

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7 January 2021

Selegiline is neuroprotective in primary brain cultures treated with 1-methyl-4-phenylpyridinium

1 reference

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7 January 2021

Glyceraldehyde-3-phosphate dehydrogenase, the putative target of the antiapoptotic compounds CGP 3466 and R-(-)-deprenyl

1 reference

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The mitochondrial death/life regulator in apoptosis and necrosis

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Effect of long-term treatment with selective monoamine oxidase A and B inhibitors on dopamine release from rat striatum in vivo.

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7 January 2021

Clinical pharmacokinetics and pharmacodynamics of selegiline. An update

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An endogenous dopaminergic neurotoxin, N-methyl-(R)-salsolinol, induces DNA damage in human dopaminergic neuroblastoma SH-SY5Y cells

1 reference

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7 January 2021

(-)-Deprenyl protects human dopaminergic neuroblastoma SH-SY5Y cells from apoptosis induced by peroxynitrite and nitric oxide

1 reference

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7 January 2021

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7 January 2021

Enantio-specific induction of apoptosis by an endogenous neurotoxin, N-methyl(R)salsolinol, in dopaminergic SH-SY5Y cells: suppression of apoptosis by N-(2-heptyl)-N-methylpropargylamine

1 reference

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7 January 2021

Transfection-enforced Bcl-2 overexpression and an anti-Parkinson drug, rasagiline, prevent nuclear accumulation of glyceraldehyde-3-phosphate dehydrogenase induced by an endogenous dopaminergic neurotoxin, N-methyl(R)salsolinol

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900221-0

7 January 2021

The anti-Parkinson drug, rasagiline, prevents apoptotic DNA damage induced by peroxynitrite in human dopaminergic neuroblastoma SH-SY5Y cells

1 reference

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7 January 2021

Deprenyl protects dopamine neurons from the neurotoxic effect of 1-methyl-4-phenylpyridinium ion.

1 reference

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7 January 2021

Oxidation of N-methyl(R)salsolinol: involvement to neurotoxicity and neuroprotection by endogenous catechol isoquinolines.

1 reference

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7 January 2021

Apoptosis induced by an endogenous neurotoxin, N-methyl(R)salsolinol, in dopamine neurons

1 reference

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7 January 2021

Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria

1 reference

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7 January 2021

Effects of tocopherol and deprenyl on the progression of disability in early Parkinson's disease

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The cytotoxicity of tumor necrosis factor depends on induction of the mitochondrial permeability transition

1 reference

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7 January 2021

Transition Metals, Ferritin, Glutathione, and Ascorbic Acid in Parkinsonian Brains

1 reference

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7 January 2021

Selegiline enhances NGF synthesis and protects central nervous system neurons from excitotoxic and ischemic damage.

1 reference

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7 January 2021

Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC

1 reference

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7 January 2021

Sparing by rasagiline (TVP-1012) of cholinergic functions and behavior in the postnatal anoxia rat.

1 reference

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7 January 2021

Increased caspase 3 and Bax immunoreactivity accompany nuclear GAPDH translocation and neuronal apoptosis in Parkinson's disease

1 reference

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7 January 2021

(-)-Deprenyl reduces PC12 cell apoptosis by inducing new protein synthesis

1 reference

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7 January 2021

Modulation of gene expression rather than monoamine oxidase inhibition: (-)-deprenyl-related compounds in controlling neurodegeneration

1 reference

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7 January 2021

Apoptosis in the pathogenesis and treatment of disease

1 reference

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7 January 2021

Bcl-2 family: life-or-death switch

1 reference

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7 January 2021

Mitochondrial membrane potential and nuclear changes in apoptosis caused by serum and nerve growth factor withdrawal: time course and modification by (-)-deprenyl.

1 reference

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7 January 2021

The anti-Parkinson drug rasagiline and its cholinesterase inhibitor derivatives exert neuroprotection unrelated to MAO inhibition in cell culture and in vivo

1 reference

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7 January 2021

Aliphatic propargylamines: potent, selective, irreversible monoamine oxidase B inhibitors

1 reference

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7 January 2021

Neurochemical and neuroprotective effects of some aliphatic propargylamines: new selective nonamphetamine-like monoamine oxidase B inhibitors.

1 reference

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7 January 2021

Inhibitors of permeability transition interfere with the disruption of the mitochondrial transmembrane potential during apoptosis.

1 reference

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7 January 2021

Neuroprotection by R(-)-deprenyl and N-2-hexyl-N-methylpropargylamine on DSP-4, a neurotoxin, induced degeneration of noradrenergic neurons in the rat locus coeruleus

1 reference

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7 January 2021

10.1016/S0892-0362(02)00221-0

Identifiers

DOI

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4 August 2017

1 reference