The role of extended-release niacin on immune activation and neurocognition in HIV-infected patients treated with antiretroviral therapy - CTN PT006: study protocol for a randomized controlled trial (Q34812071)

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English	The role of extended-release niacin on immune activation and neurocognition in HIV-infected patients treated with antiretroviral therapy - CTN PT006: study protocol for a randomized controlled trial	scientific article

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scholarly article

1 reference

Europe PubMed Central

4 August 2017

The role of extended-release niacin on immune activation and neurocognition in HIV-infected patients treated with antiretroviral therapy - CTN PT006: study protocol for a randomized controlled trial (English)

1 reference

Europe PubMed Central

4 August 2017

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

Jean-Pierre Routy

9

object named as

Jean-Pierre Routy

1 reference

Europe PubMed Central

4 August 2017

Mohammad-Ali Jenabian

2

object named as

Mohammad-Ali Jenabian

1 reference

Europe PubMed Central

4 August 2017

Bertrand Lebouché

1

object named as

Bertrand Lebouché

1 reference

Europe PubMed Central

4 August 2017

5

object named as

Kim Engler

1 reference

Europe PubMed Central

4 August 2017

7

object named as

Réjean Thomas

1 reference

Europe PubMed Central

4 August 2017

Benoit Trottier

6

object named as

Benoit Trottier

1 reference

Europe PubMed Central

4 August 2017

Marie-Josée Brouillette

8

object named as

Marie-Josée Brouillette

1 reference

Europe PubMed Central

4 August 2017

author name string

Joel Singer

3

1 reference

Europe PubMed Central

4 August 2017

Gina M Graziani

4

1 reference

Europe PubMed Central

4 August 2017

publication date

7 October 2014

1 reference

Europe PubMed Central

4 August 2017

1 reference

Europe PubMed Central

4 August 2017

15

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Europe PubMed Central

4 August 2017

390

1 reference

Europe PubMed Central

4 August 2017

https://scigraph.springernature.com/pub.10.1186/1745-6215-15-390

0 references

HIV infection: epidemiology, pathogenesis, treatment, and prevention

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Immuno-virological discordance and the risk of non-AIDS and AIDS events in a large observational cohort of HIV-patients in Europe

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Long-term mortality in HIV-positive individuals virally suppressed for >3 years with incomplete CD4 recovery.

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8 July 2018

Distinct tryptophan catabolism and Th17/Treg balance in HIV progressors and elite controllers

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8 July 2018

Systemic effects of inflammation on health during chronic HIV infection

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8 July 2018

Indoleamine 2,3 dioxygenase and metabolic control of immune responses

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Niacin in patients with low HDL cholesterol levels receiving intensive statin therapy

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8 July 2018

Tryptophan, Neurodegeneration and HIV-Associated Neurocognitive Disorder

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Kynurenine pathway metabolites in humans: disease and healthy States

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8 July 2018

CD4 nadir is a predictor of HIV neurocognitive impairment in the era of combination antiretroviral therapy

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Th17 and regulatory T cells: implications for AIDS pathogenesis

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8 July 2018

Tryptophan catabolism by indoleamine 2,3-dioxygenase 1 alters the balance of TH17 to regulatory T cells in HIV disease

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8 July 2018

Pretreatment levels of soluble cellular receptors and interleukin-6 are associated with HIV disease progression in subjects treated with highly active antiretroviral therapy

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8 July 2018

A "hot" topic in dyslipidemia management--"how to beat a flush": optimizing niacin tolerability to promote long-term treatment adherence and coronary disease prevention.

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8 July 2018

Pathogenesis of HIV infection: total CD4+ T-cell pool, immune activation, and inflammation

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Effect of niacin therapy on cardiovascular outcomes in patients with coronary artery disease

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Neurocognitive functioning in HIV-1 infection: effects of cerebrovascular risk factors and age

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8 July 2018

Increased tissue factor expression on circulating monocytes in chronic HIV infection: relationship to in vivo coagulation and immune activation

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8 July 2018

What's the deal with niacin development: is laropiprant add-on therapy a winning strategy to beat a straight flush?

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8 July 2018

The absence of CD4+ T cell count recovery despite receipt of virologically suppressive highly active antiretroviral therapy: clinical risk, immunological gaps, and therapeutic options

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8 July 2018

Incomplete reconstitution of T cell subsets on combination antiretroviral therapy in the AIDS Clinical Trials Group protocol 384.

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8 July 2018

Emerging concepts in the immunopathogenesis of AIDS

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8 July 2018

Poor initial CD4+ recovery with antiretroviral therapy prolongs immune depletion and increases risk for AIDS and non-AIDS diseases

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283109

8 July 2018

CD4+ count and risk of non-AIDS diseases following initial treatment for HIV infection

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283109

8 July 2018

The immune-mediated alteration of serotonin and glutamate: towards an integrated view of depression

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Diminished quality of life in patients with cancer correlates with tryptophan degradation

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Prevalence and risk factors for human immunodeficiency virus-associated neurocognitive impairment, 1996 to 2002: results from an urban observational cohort

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Uniform requirements for manuscripts submitted to biomedical journals: writing and editing for biomedical publication

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8 July 2018

Tryptophan depletion and HIV infection: a metabolic link to pathogenesis

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8 July 2018

Tryptophan deprivation sensitizes activated T cells to apoptosis prior to cell division

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8 July 2018

Increased plasma tryptophan in HIV-infected patients treated with pharmacologic doses of nicotinamide

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Inhibition of T cell proliferation by macrophage tryptophan catabolism

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Epidemiology of potential association between L-tryptophan ingestion and eosinophilia-myalgia syndrome

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Insights into therapy: tryptophan oxidation and HIV infection

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Effective antiretroviral therapy reduces degradation of tryptophan in patients with HIV-1 infection

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Tryptophan loading induces oxidative stress

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Sustained-release niacin for prevention of migraine headache

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Superiority of antagonic-stress composition versus nicergoline in gerontopsychiatry.

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Validation of a simplified medication adherence questionnaire in a large cohort of HIV-infected patients: the GEEMA Study

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Immunophenotypic patterns of CD8+ T cell subsets expressing CD8alphaalpha and IL-7Ralpha in viremic, aviremic and slow progressor HIV-1-infected subjects.

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21 January 2018

Plasma tryptophan, kynurenine and 3-hydroxykynurenine measurement using automated on-line solid-phase extraction HPLC-tandem mass spectrometry.

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Persistent human immunodeficiency virus-1 antigenaemia affects the expression of interleukin-7Ralpha on central and effector memory CD4+ and CD8+ T cell subsets

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21 January 2018

The immune effects of TRYCATs (tryptophan catabolites along the IDO pathway): relevance for depression - and other conditions characterized by tryptophan depletion induced by inflammation

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26 October 2018

Effective antiretroviral therapy reduces degradation of tryptophan in patients with HIV-1 infection.

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26 October 2018

CD4 T-cell hyperactivation and susceptibility to cell death determine poor CD4 T-cell recovery during suppressive HAART

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Multiple-dose efficacy and safety of an extended-release form of niacin in the management of hyperlipidemia

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Computerized assessment in neuropsychiatry using CANTAB: discussion paper

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Influence of RANTES, SDF-1 and TGF-beta levels on the value of interleukin-7 as a predictor of virological response in HIV-1-infected patients receiving double boosted protease inhibitor-based therapy

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10.1186/1745-6215-15-390

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