Nuclear factor-kappa B and cancer: its role in prevention and therapy (Q34816089)

4 August 2017

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title

Nuclear factor-kappa B and cancer: its role in prevention and therapy (English)

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4 August 2017

Alok C Bharti

1

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PubMed ID

12213582

4 August 2017

Bharat B Aggarwal

series ordinal

2

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PubMed ID

12213582

4 August 2017

language of work or name

English

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publication date

1 September 2002

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4 August 2017

Biochemical Pharmacology

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4 August 2017

64

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4 August 2017

5-6

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4 August 2017

883-888

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Inducibility of kappa immunoglobulin enhancer-binding protein Nf-kappa B by a posttranslational mechanism

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Nuclear factor-kappaB activation: a question of life or death

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Transcriptional regulation of endothelial cell adhesion molecules: NF-kappa B and cytokine-inducible enhancers.

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New insights into the role of nuclear factor-kB in cell growth regulation

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NF-kappa B: a lesson in family values

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NF-kappa B: ten years after

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The NF-kappa B and I kappa B proteins: new discoveries and insights

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Activators and target genes of Rel/NF-kappaB transcription factors

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The beginning of the end: IkappaB kinase (IKK) and NF-kappaB activation

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Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappaB.

7 January 2021

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Benzo[a]pyrene induces the transcription of cyclooxygenase-2 in vascular smooth muscle cells. Evidence for the involvement of extracellular signal-regulated kinase and NF-kappaB.

7 January 2021

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The induction of cyclooxygenase-1 by a tobacco carcinogen in U937 human macrophages is correlated to the activation of NF-kappaB

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Ionizing radiation and short wavelength UV activate NF-kappaB through two distinct mechanisms

7 January 2021

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Phorbol-ester-induced activation of the NF-kappa B transcription factor involves dissociation of an apparently cytoplasmic NF-kappa B/inhibitor complex

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A role for NF-kappaB-dependent gene transactivation in sunburn.

7 January 2021

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An essential role for NF-kappaB in preventing TNF-alpha-induced cell death

7 January 2021

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TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

7 January 2021

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Suppression of TNF-alpha-induced apoptosis by NF-kappaB

7 January 2021

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Antiproliferative effects of IFN-alpha correlate with the downregulation of nuclear factor-kappa B in human Burkitt lymphoma Daudi cells

7 January 2021

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Curcumin downregulates cell survival mechanisms in human prostate cancer cell lines

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Nuclear transcription factor-kappaB as a target for cancer drug development

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Constitutive nuclear factor-kappaB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells

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The NF-kappa B transcription factor and cancer: high expression of NF-kappa B- and I kappa B-related proteins in tumor cell lines

7 January 2021

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Constitutive activation of NF-kappaB causes resistance to apoptosis in human cutaneous T cell lymphoma HuT-78 cells. Autocrine role of tumor necrosis factor and reactive oxygen intermediates

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Use of in vitro assays to predict the efficacy of chemopreventive agents in whole animals

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Activation of nuclear factor kappa B in human lymphoblastoid cells by low-dose ionizing radiation

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Curcumin causes the growth arrest and apoptosis of B cell lymphoma by downregulation of egr-1, c-myc, bcl-XL, NF-kappa B, and p53.

7 January 2021

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Making decisions through Myc.

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In vivo inhibition of nitric oxide synthase gene expression by curcumin, a cancer preventive natural product with anti-inflammatory properties.

7 January 2021

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Posttranslational regulation of cyclin D1 by retinoic acid: a chemoprevention mechanism

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Osteopontin stimulates tumor growth and activation of promatrix metalloproteinase-2 through nuclear factor-kappa B-mediated induction of membrane type 1 matrix metalloproteinase in murine melanoma cells

7 January 2021

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Nuclear factor kappa B is a molecular target for sulforaphane-mediated anti-inflammatory mechanisms.

7 January 2021

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Anoxia-induced up-regulation of interleukin-8 in human malignant melanoma. A potential mechanism for high tumor aggressiveness

7 January 2021

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Overexpression of urokinase-type plasminogen activator in pancreatic adenocarcinoma is regulated by constitutively activated RelA

7 January 2021

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Bcl-xL and Bcl-2 expression in squamous cell carcinoma of the head and neck.

7 January 2021

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Over-expression of bcl-xL gene in human gastric adenomas and carcinomas.

7 January 2021

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Expression of proangiogenic chemokine Gro 1 in low and high metastatic variants of Pam murine squamous cell carcinoma is differentially regulated by IL-1alpha, EGF and TGF-beta1 through NF-kappaB dependent and independent mechanisms

7 January 2021

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Inhibitory effects of curcumin and capsaicin on phorbol ester-induced activation of eukaryotic transcription factors, NF-kappaB and AP-1.

7 January 2021

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Induction of the differentiation of HL-60 promyelocytic leukemia cells by vitamin E and other antioxidants in combination with low levels of vitamin D3: possible relationship to NF-kappaB

7 January 2021

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Protein tyrosine kinase inhibitors block tumor necrosis factor-induced activation of nuclear factor-kappaB, degradation of IkappaBalpha, nuclear translocation of p65, and subsequent gene expression

7 January 2021

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Resveratrol suppresses TNF-induced activation of nuclear transcription factors NF-kappa B, activator protein-1, and apoptosis: potential role of reactive oxygen intermediates and lipid peroxidation

7 January 2021

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Suppression of tumor necrosis factor-activated nuclear transcription factor-kappaB, activator protein-1, c-Jun N-terminal kinase, and apoptosis by beta-lapachone

7 January 2021

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Sulindac inhibits activation of the NF-kappaB pathway

7 January 2021

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Inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced NF-kappaB activation by tea polyphenols, (-)-epigallocatechin gallate and theaflavins

7 January 2021

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Aspirin-induced activation of the NF-kappaB signaling pathway: a novel mechanism for aspirin-mediated apoptosis in colon cancer cells

7 January 2021

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Caffeic acid phenethyl ester is a potent and specific inhibitor of activation of nuclear transcription factor NF-kappa B

7 January 2021

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Chemoprevention of colonic aberrant crypt foci by an inducible nitric oxide synthase-selective inhibitor.

7 January 2021

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Anethole blocks both early and late cellular responses transduced by tumor necrosis factor: effect on NF-kappaB, AP-1, JNK, MAPKK and apoptosis

7 January 2021

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Wortmannin inhibits activation of nuclear transcription factors NF-kappaB and activated protein-1 induced by lipopolysaccharide and phorbol ester

7 January 2021

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Emodin (3-methyl-1,6,8-trihydroxyanthraquinone) inhibits TNF-induced NF-kappaB activation, IkappaB degradation, and expression of cell surface adhesion proteins in human vascular endothelial cells.

7 January 2021

1 reference

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10.1016/S0006-2952(02)01154-1

7 January 2021

Identifiers

DOI

1 reference

4 August 2017

1 reference

PubMed ID

12213582