B cell receptors in TCL1 transgenic mice resemble those of aggressive, treatment-resistant human chronic lymphocytic leukemia (Q34830865)

4 August 2017

B cell receptors in TCL1 transgenic mice resemble those of aggressive, treatment-resistant human chronic lymphocytic leukemia (English)

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chronic lymphocytic leukemia

4 August 2017

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9

Carlo M Croce

1 reference

4 August 2017

Alan Sawyer

5

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Dimitar Efremov

object named as

Dimitar G Efremov

8

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author name string

Xiao-jie Yan

1

1 reference

4 August 2017

Emilia Albesiano

2

1 reference

4 August 2017

Nicola Zanesi

3

1 reference

4 August 2017

Sophia Yancopoulos

4

1 reference

4 August 2017

Egidio Romano

6

1 reference

4 August 2017

Aleksandar Petlickovski

7

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4 August 2017

Nicholas Chiorazzi

10

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4 August 2017

language of work or name

English

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publication date

24 July 2006

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Proceedings of the National Academy of Sciences of the United States of America

4 August 2017

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4 August 2017

103

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4 August 2017

31

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4 August 2017

11713-11718

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Complete sequence assembly and characterization of the C57BL/6 mouse Ig heavy chain V region

4 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518806

Chronic lymphocytic leukemia: molecular genetics and animal models

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518806

Identification of novel VH1/J558 immunoglobulin germline genes of C57BL/6 (Igh b) allotype

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518806

Unmutated and mutated chronic lymphocytic leukemias derive from self-reactive B cell precursors despite expressing different antibody reactivity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518806

Chronic lymphocytic leukemia

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518806

Sustained signaling through the B-cell receptor induces Mcl-1 and promotes survival of chronic lymphocytic leukemia B cells.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518806

TNF receptor-associated factor (TRAF) domain and Bcl-2 cooperate to induce small B cell lymphoma/chronic lymphocytic leukemia in transgenic mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518806

Multiple distinct sets of stereotyped antigen receptors indicate a role for antigen in promoting chronic lymphocytic leukemia

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518806

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518806

Regulation of B-cell development by antibody specificity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518806

Chronic lymphocytic leukemia: revelations from the B-cell receptor.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518806

Selection during development of VH11+ B cells: a model for natural autoantibody-producing CD5+ B cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518806

Expressed murine and human CDR-H3 intervals of equal length exhibit distinct repertoires that differ in their amino acid composition and predicted range of structures

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518806

B cell chronic lymphocytic leukemia: lessons learned from studies of the B cell antigen receptor

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518806

Targeting mature T cell leukemia: new understanding of molecular pathways

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518806

Human chronic lymphocytic leukemia modeled in mouse by targeted TCL1 expression

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518806

Autoreactivity by design: innate B and T lymphocytes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518806

Somatically mutated Ig V(H)3-21 genes characterize a new subset of chronic lymphocytic leukemia

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518806

Autoreactive B cells in the marginal zone that express dual receptors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518806

Genomic aberrations and survival in chronic lymphocytic leukemia

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518806

B-cell subsets and the mature preimmune repertoire. Marginal zone and B1 B cells as part of a "natural immune memory".

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518806

Tcl1 enhances Akt kinase activity and mediates its nuclear translocation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518806

Cellular survival: a play in three Akts

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518806

Unmutated Ig V(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518806

Ig V gene mutation status and CD38 expression as novel prognostic indicators in chronic lymphocytic leukemia

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518806

The 5' part of the mouse immunoglobulin kappa locus

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518806

The complete nucleotide sequence of the human immunoglobulin heavy chain variable region locus

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518806

Chronic lymphocytic leukemia B cells express restricted sets of mutated and unmutated antigen receptors.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518806

Frequent occurrence of identical heavy and light chain Ig rearrangements

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518806

Ig VH1 genes expressed in B cell chronic lymphocytic leukemia exhibit distinctive molecular features

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518806

Sequence and evolution of the human germline V lambda repertoire

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518806

Deletional mapping of fifteen mouse VH gene families reveals a common organization for three Igh haplotypes.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518806

The V kappa genes of the L regions and the repertoire of V kappa gene sequences in the human germ line

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518806

Identification of the TCL1 gene involved in T-cell malignancies

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518806

Somatic diversification and selection of immunoglobulin heavy and light chain variable region genes in IgG+ CD5+ chronic lymphocytic leukemia B cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518806

The pathogenesis of chronic lymphocytic leukemia: analysis of the antibody repertoire

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518806

The "Ly-1 B" cell subpopulation in normal immunodefective, and autoimmune mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518806

New trends in CLL treatment

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518806

Growth and selection of B cells in vivo.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518806

A single VH gene is utilized predominantly in anti-BrMRBC hybridomas derived from purified Ly-1 B cells. Definition of the VH11 family.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518806

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518806

Production of autoantibodies by CD5-expressing B lymphocytes from patients with chronic lymphocytic leukemia

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518806

Sequence homologies, N sequence insertion and JH gene utilization in VHDJH joining: implications for the joining mechanism and the ontogenetic timing of Ly1 B cell and B-CLL progenitor generation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518806

The V kappa gene repertoire in the human germ line

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518806

Chronic lymphocytic leukemias utilizing the VH3-21 gene display highly restricted Vlambda2-14 gene use and homologous CDR3s: implicating recognition of a common antigen epitope.

8 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0604564103

Subsets with restricted immunoglobulin gene rearrangement features indicate a role for antigen selection in the development of chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0604564103

Chronic lymphocytic leukemia B cells of more than 1% of patients express virtually identical immunoglobulins

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0604564103

The murine Tcl1 oncogene: embryonic and lymphoid cell expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0604564103

Effect of rapamycin on mouse chronic lymphocytic leukemia and the development of nonhematopoietic malignancies in Emu-TCL1 transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0604564103

The variable genes and gene families of the mouse immunoglobulin kappa locus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0604564103

The central part of the mouse immunoglobulin kappa locus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0604564103

Development of the expressed Ig CDR-H3 repertoire is marked by focusing of constraints in length, amino acid use, and charge that are first established in early B cell progenitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0604564103

Immunoglobulin light chain repertoire in chronic lymphocytic leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0604564103

Normal B cells express 51p1-encoded Ig heavy chains that are distinct from those expressed by chronic lymphocytic leukemia B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0604564103

Mechanisms that limit the diversity of antibody: three sequentially acting mechanisms that favor the spontaneous production of germline encoded anti-phosphatidyl choline.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0604564103

Marginal zone and B1 B cells unite in the early response against T-independent blood-borne particulate antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0604564103

Endocrine disruptors (environmental estrogens) enhance autoantibody production by B1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0604564103

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0604564103

Geographic patterns and pathogenetic implications of IGHV gene usage in chronic lymphocytic leukemia: the lesson of the IGHV3-21 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0604564103

Evidence that chronic lymphocytic leukemia B lymphocytes are frequently committed to production of natural autoantibodies

21 January 2018

1 reference

12 December 2020

Evidence for differential responsiveness of human CD5+ and CD5- B cell subsets to T cell-independent mitogens

1 reference

12 December 2020

The NZB mouse as a model for chronic lymphocytic leukemia

1 reference

12 December 2020

Evidence for selection of a population of multi-reactive B cells into the splenic marginal zone

1 reference

12 December 2020

Chronic lymphocytic leukemic (CLL) cells secrete multispecific autoantibodies

1 reference

12 December 2020

TCL1 shows a regulated expression pattern in chronic lymphocytic leukemia that correlates with molecular subtypes and proliferative state

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0604564103

1 reference

4 August 2017

0 references

1 reference

4 August 2017

1 reference