A benefit-risk assessment of medical treatment for uterine leiomyomas (Q34836796)

4 August 2017

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title

A benefit-risk assessment of medical treatment for uterine leiomyomas (English)

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4 August 2017

Vincenzo De Leo

1

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4 August 2017

Giuseppe Morgante

2

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4 August 2017

Antonio La Marca

3

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4 August 2017

Maria Concetta Musacchio

4

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4 August 2017

Massimo Sorace

5

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4 August 2017

Chiara Cavicchioli

6

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4 August 2017

Felice Petraglia

7

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4 August 2017

1 January 2002

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4 August 2017

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4 August 2017

25

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4 August 2017

11

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4 August 2017

759-779

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https://scigraph.springernature.com/pub.10.2165/00002018-200225110-00002

4 August 2017

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Treatment of uterine fibroids with a slow-release formulation of the gonadotrophin releasing hormone antagonist Cetrorelix.

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Goserelin therapy before surgery for uterine fibroids

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The New Steroid Analog RU 486 Inhibits Glucocorticoid Action in Man

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Regression of uterine leiomyomata in response to the antiprogesterone RU 486.

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Oestrogen deficiency causes DNA damage in uterine leiomyoma cells: a possible mechanism for shrinkage of fibroids by GnRH agonists

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Goserelin. A review of its pharmacodynamic and pharmacokinetic properties, and clinical use in sex hormone-related conditions

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Development after exposure to mifepristone in early pregnancy

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Increased expression of messenger RNA for collagen type I, collagen type III, and fibronectin in myometrium of pregnancy.

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Antigonadotropin (danazol) in the treatment of endometriosis. Evaluation of posttreatment fertility and three-year follow-up data

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Recurrence of myomas after myomectomy in women pretreated with leuprolide acetate depot or placebo

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12 December 2020

Treatment of leiomyomata with intranasal or subcutaneous leuprolide, a gonadotropin-releasing hormone agonist

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12 December 2020

The secretion of insulin-like growth factors I and II by explant cultures of fibroids and myometrium from women treated with a gonadotropin-releasing hormone agonist

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12 December 2020

Endocrine responses to long-term administration of the antiprogesterone RU486 in patients with pelvic endometriosis

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12 December 2020

Danazol binding and translocation of steroid receptors

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12 December 2020

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A prospective, randomized trial of gonadotropin-releasing hormone agonist plus estrogen-progestin or progestin "add-back" regimens for women with leiomyomata uteri

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Analysis of androgen receptor DNA reveals the independent clonal origins of uterine leiomyomata and the secondary nature of cytogenetic aberrations in the development of leiomyomata

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Remarkable and persistent shrinkage of uterine leiomyoma associated with interferon alfa treatment for hepatitis

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Mitotic activity in uterine leiomyomas during the menstrual cycle

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Epidemiologic characteristics of women with uterine fibroids: a case-control study

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Danazol concentrations in human ovarian follicular fluid and their relationship to simultaneous serum concentrations

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Estrogen receptor gene expression in human uterine leiomyomata

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Early miscarriage and fetal malformations after induction of ovulation (by clomiphene citrate and/or human menotropins), in vitro fertilization, and gamete intrafallopian transfer

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Progestational activity of danazol in the human female subject

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12 December 2020

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Long-term follow-up of patients with uterine fibroids after treatment with the LHRH agonist buserelin

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12 December 2020

Perinatal outcome of pregnancy after GnRH antagonist (ganirelix) treatment during ovarian stimulation for conventional IVF or ICSI: a preliminary report

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12 December 2020

Insulin-like growth factor (IGF), IGF binding protein (IGFBP), and IGF receptor gene expression and IGFBP synthesis in human uterine leiomyomata

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12 December 2020

Uterine leiomyomata--a feature of acromegaly

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12 December 2020

Normal development after exposure to mifepristone in early pregnancy

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12 December 2020

Hypogonadism induced by luteinising hormone releasing hormone agonist analogues: effects on bone density in premenopausal women.

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12 December 2020

Termination of early gestation with the anti-progestin steroid RU 486: medium versus low dose

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12 December 2020

Uterine leiomyomata: etiology, symptomatology, and management.

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12 December 2020

Danazol administration after gonadotrophin-releasing hormone analogue reduces rebound of uterine myomas

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12 December 2020

Treatment with the gonadotrophin-releasing hormone antagonist ganirelix in women undergoing ovarian stimulation with recombinant follicle stimulating hormone is effective, safe and convenient: results of a controlled, randomized, multicentre trial.

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12 December 2020

An evaluation of the effect of gonadotropin-releasing hormone analogs and medroxyprogesterone acetate on uterine leiomyomata volume by magnetic resonance imaging: a prospective, randomized, double blind, placebo-controlled, crossover trial

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12 December 2020

Long-term treatment of leiomyomas with gestrinone

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12 December 2020

Preclinical evidence for therapeutic efficacy of selective estrogen receptor modulators for uterine leiomyoma

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12 December 2020

Effects of progesterone on uterine leiomyoma growth and apoptosis

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12 December 2020

Uterine fibroids: a clinical review

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12 December 2020

Purification, amino acid composition and N-terminus of the hypothalamic luteinizing hormone releasing factor (LRF) of ovine origin.

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12 December 2020

Treatment of large fibroids with high doses of gestrinone

1 reference

12 December 2020

Noncompetitive antiestrogenic effect of RU 486 in blocking the estrogen-stimulated luteinizing hormone surge and the proliferative action of estradiol on endometrium in castrate monkeys

1 reference

12 December 2020

The Endocrine Effects of Long-Term Treatment with Mifepristone (RU 486)

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12 December 2020

Isolation, synthesis, and biological activity of five metabolites of danazol

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12 December 2020

Clinical significance of cytogenetic abnormalities in uterine myomas

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12 December 2020

The frequency of uterine leiomyomas

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12 December 2020

Interferon-alpha is a potent inhibitor of basic fibroblast growth factor-stimulated cell proliferation in human uterine cells.

1 reference

12 December 2020

Growth hormone receptor messenger ribonucleic acid expression in leiomyoma and surrounding myometrium

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12 December 2020

A placebo-controlled trial of a depot gonadotropin-releasing hormone analogue (leuprolide) in the treatment of uterine leiomyomata.

1 reference

12 December 2020

Tamoxifen prolongs luteal phase in premenopausal women but has no effect on the size of uterine fibroids

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12 December 2020

Danazol: molecular, endocrine, and clinical pharmacology.

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12 December 2020

Further studies of steoidal inhibitors of delpha5, 3beta-hydroxysteroid dehydrogenase and delta5-delta4, 3-ketosteroid isomerase in Pseudomonas testosteroni and in bovine adrenals

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12 December 2020

Gestrinone in the treatment of myomas

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12 December 2020

Endocrine Properties and Clinical Application of Danazol

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12 December 2020

Danazol binding to rat androgen, glucocorticoid, progesterone, and estrogen receptors: correlation with biologic activity

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12 December 2020

Danazol in the treatment of endometriosis: analysis of 100 cases with a 4-year follow-up

1 reference

12 December 2020

Hysterectomy and race.

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12 December 2020

Deliveries and children born after in-vitro fertilisation in Sweden 1982-95: a retrospective cohort study

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12 December 2020

The antiprogestational agent RU 486 as an abortifacient in early human pregnancy: a comparison of three dose regimens

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12 December 2020

Synthesis and biological activity of some very hydrophobic superagonist analogues of luteinizing hormone-releasing hormone

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12 December 2020

Births in Great Britain resulting from assisted conception, 1978-87. MRC Working Party on Children Conceived by In Vitro Fertilisation

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12 December 2020

Rapid regression of uterine leiomyomas in response to daily administration of gonadotropin-releasing hormone antagonist

1 reference

12 December 2020

Exposure to platelet-derived growth factor modulates the porcine aortic smooth muscle cell response to somatomedin-C.

1 reference

12 December 2020

Prospective follow-up study of 877 children born after intracytoplasmic sperm injection (ICSI), with ejaculated epididymal and testicular spermatozoa and after replacement of cryopreserved embryos obtained after ICSI.

1 reference

12 December 2020

Tolerance of perinidatory primate embryos to RU 486 exposure in vitro and in vivo

1 reference

12 December 2020

Danazol inhibits steroidogenesis

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12 December 2020

Short-term treatment of uterine fibromyomas with danazol.

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12 December 2020

Efficacy and safety considerations in women with uterine leiomyomas treated with gonadotropin-releasing hormone agonists: the estrogen threshold hypothesis

1 reference

12 December 2020

Changes in the SHBG concentration during danazol treatment

1 reference

12 December 2020

Endocrine effects and pharmacokinetic characteristics of a potent new gonadotropin-releasing hormone antagonist (Ganirelix) with minimal histamine-releasing properties: studies in postmenopausal women

1 reference

12 December 2020

Randomized control study of the effects of raloxifene on serum lipids and homocysteine in older women.

1 reference

12 December 2020

A radioimmunoassay for danazol (17alpha-pregna-2,4-dien-20-yno[2,3-d]isoxazol-17-ol)

1 reference

12 December 2020

Endocrine effects of danazol in the treatment of endometriosis

1 reference

12 December 2020

Long-acting gonadotropin hormone-releasing hormone analog used to treat uteri

1 reference

12 December 2020

Toward removing uterine fibroids without surgery: subcutaneous infusion of a luteinizing hormone-releasing hormone agonist commencing in the luteal phase

1 reference

12 December 2020

Danazol and urogenital sinus formation in pregnancy

1 reference

12 December 2020

Pharmacokinetics and endocrine effects of slow release formulations of LHRH analogues

1 reference

12 December 2020

Shrinkage of uterine fibroids during therapy with goserelin (Zoladex): a luteinizing hormone-releasing hormone agonist administered as a monthly subcutaneous depot

1 reference

12 December 2020

The role of tamoxifen in the treatment of symptomatic uterine leiomyomata -- a pilot study

1 reference

12 December 2020

Progesterone induction of 17beta-hydroxysteroid dehydrogenase type 2 during the secretory phase occurs in the endometrium of estrogen-dependent benign diseases but not in normal endometrium

1 reference

12 December 2020

Genotype distribution of estrogen receptor-alpha gene polymorphisms in Italian women with surgical uterine leiomyomas

1 reference

12 December 2020

Goserelin. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in benign gynaecological disorders

1 reference

12 December 2020

Raloxifene, tamoxifen, nafoxidine, or estrogen effects on reproductive and nonreproductive tissues in ovariectomized rats

1 reference

12 December 2020

Ethnic variation in estrogen and progesterone receptor concentration in leiomyoma and normal myometrium

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12 December 2020

Sex steroid receptors in human myometrium and fibroids: changes during the menstrual cycle and gonadotropin-releasing hormone treatment.

1 reference

12 December 2020

Transport of steroid hormones: interaction of 70 drugs with testosterone-binding globulin and corticosteroid-binding globulin in human plasma

1 reference

12 December 2020

Danazol inhibits human adrenal 21-and 11 beta-hydroxylation in vitro

1 reference

12 December 2020

Mifepristone (RU 486)--a modulator of progestin and glucocorticoid action

1 reference

12 December 2020

Gonadotropin-releasing hormone analog design. Structure-function studies toward the development of agonists and antagonists: rationale and perspective

1 reference

12 December 2020

Aromatase activity in uterine leiomyomata

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12 December 2020

Treatment of unresectable meningiomas with the antiprogesterone agent mifepristone

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12 December 2020

Comparison of bimanual examination with ultrasound examination before hysterectomy for uterine leiomyoma.

1 reference

12 December 2020

Administration of somatostatin analogue reduces uterine and myoma volume in women with uterine leiomyomata.

1 reference

12 December 2020

A Danish national cohort of 730 infants born after intracytoplasmic sperm injection (ICSI) 1994-1997.

1 reference

12 December 2020

Termination of early pregnancy by the progesterone antagonist RU 486 (Mifepristone)

1 reference

12 December 2020

Danazol—a Synthetic Steroid Derivative with Interesting Physiologic Properties

1 reference

12 December 2020

Effects of raloxifene treatment on uterine leiomyomas in postmenopausal women

1 reference

12 December 2020

Treatment of leiomyomata uteri with short-term leuprolide followed by leuprolide plus estrogen-progestin hormone replacement therapy for 2 years: a pilot study

1 reference

12 December 2020

Effect of growth hormone and its combination with estradiol-17 beta on the uterus of hypophysectomized and hypophysectomized-ovariectomized rats

1 reference

12 December 2020

Treatment of uterine leiomyomas with luteinizing hormone-releasing hormone antagonist Cetrorelix

1 reference

12 December 2020

Effects of raloxifene in a guinea pig model for leiomyomas

1 reference

12 December 2020

A clinical trial of the effects of tibolone administered with gonadotropin-releasing hormone analogues for the treatment of uterine leiomyomata.

1 reference

12 December 2020

Use of intranasal luteinizing hormone-releasing hormone agonist in uterine leiomyomas

1 reference

12 December 2020

A double-blind, randomized, dose-finding study to assess the efficacy of the gonadotrophin-releasing hormone antagonist ganirelix (Org 37462) to prevent premature luteinizing hormone surges in women undergoing ovarian stimulation with recombinant fo

1 reference

12 December 2020

Production of prolactin by smooth muscle cells cultured from human uterine fibroid tumors

1 reference

12 December 2020

10.2165/00002018-200225110-00002

Identifiers

DOI

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Dimensions Publication ID

4 August 2017

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