Acetyl-11-keto-β-boswellic acid suppresses invasion of pancreatic cancer cells through the downregulation of CXCR4 chemokine receptor expression (Q34861014)

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English	Acetyl-11-keto-β-boswellic acid suppresses invasion of pancreatic cancer cells through the downregulation of CXCR4 chemokine receptor expression	scientific article

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scholarly article

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Europe PubMed Central

4 August 2017

Acetyl-11-keto-β-boswellic acid suppresses invasion of pancreatic cancer cells through the downregulation of CXCR4 chemokine receptor expression (English)

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Europe PubMed Central

4 August 2017

pancreatic cancer

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based on heuristic

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author name string

Byoungduck Park

1

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Europe PubMed Central

4 August 2017

Bokyung Sung

2

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Europe PubMed Central

4 August 2017

Vivek R Yadav

3

1 reference

Europe PubMed Central

4 August 2017

Sung-Gook Cho

4

1 reference

Europe PubMed Central

4 August 2017

Mingyao Liu

5

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Europe PubMed Central

4 August 2017

Bharat B Aggarwal

6

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Europe PubMed Central

4 August 2017

language of work or name

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publication date

29 March 2011

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Europe PubMed Central

4 August 2017

International Journal of Cancer

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Europe PubMed Central

4 August 2017

129

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Europe PubMed Central

4 August 2017

1

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Europe PubMed Central

4 August 2017

23-33

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Europe PubMed Central

4 August 2017

describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3082612/fullTextXML

based on heuristic

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Antibody-drug conjugate targets

1 reference

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Acetyl-11-keto-beta-boswellic acid inhibits prostate tumor growth by suppressing vascular endothelial growth factor receptor 2-mediated angiogenesis

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8 July 2018

Boswellic acid blocks signal transducers and activators of transcription 3 signaling, proliferation, and survival of multiple myeloma via the protein tyrosine phosphatase SHP-1.

1 reference

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8 July 2018

A double blind, randomized, placebo controlled study of the efficacy and safety of 5-Loxin for treatment of osteoarthritis of the knee

1 reference

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8 July 2018

Acetyl-keto-beta-boswellic acid induces apoptosis through a death receptor 5-mediated pathway in prostate cancer cells

1 reference

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Arrestin-2 interacts with the ubiquitin-protein isopeptide ligase atrophin-interacting protein 4 and mediates endosomal sorting of the chemokine receptor CXCR4.

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8 July 2018

Transforming growth factor-beta signaling in cancer invasion and metastasis

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Role of chemokines in tumor growth

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Thiazolidinedione drugs down-regulate CXCR4 expression on human colorectal cancer cells in a peroxisome proliferator activated receptor gamma-dependent manner.

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Effect of cromolyn on S100P interactions with RAGE and pancreatic cancer growth and invasion in mouse models

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HGF induces CXCR4 and CXCL12-mediated tumor invasion through Ets1 and NF-kappaB.

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Acetyl-11-keto-beta-boswellic acid potentiates apoptosis, inhibits invasion, and abolishes osteoclastogenesis by suppressing NF-kappa B and NF-kappa B-regulated gene expression

1 reference

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The inflammatory cytokine tumor necrosis factor-alpha regulates chemokine receptor expression on ovarian cancer cells

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Up-regulation of CXCR4 expression in PC-3 cells by stromal-derived factor-1alpha (CXCL12) increases endothelial adhesion and transendothelial migration: role of MEK/ERK signaling pathway-dependent NF-kappaB activation

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Zerumbone abolishes NF-kappaB and IkappaBalpha kinase activation leading to suppression of antiapoptotic and metastatic gene expression, upregulation of apoptosis, and downregulation of invasion

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CXCR4 activation induces epidermal growth factor receptor transactivation in an ovarian cancer cell line.

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CXCR4 regulates growth of both primary and metastatic breast cancer

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Increased survival, proliferation, and migration in metastatic human pancreatic tumor cells expressing functional CXCR4.

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8 July 2018

Upregulation of CXCR4 is essential for HER2-mediated tumor metastasis.

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Chemokine receptor CXCR4 downregulated by von Hippel-Lindau tumour suppressor pVHL.

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Stromal cell-derived factor 1alpha stimulates human glioblastoma cell growth through the activation of both extracellular signal-regulated kinases 1/2 and Akt

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Boswellic acids trigger apoptosis via a pathway dependent on caspase-8 activation but independent on Fas/Fas ligand interaction in colon cancer HT-29 cells

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082612

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Vascular endothelial growth factor promotes breast carcinoma invasion in an autocrine manner by regulating the chemokine receptor CXCR4.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082612

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MMP9 potentiates pulmonary metastasis formation

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Agonist-promoted ubiquitination of the G protein-coupled receptor CXCR4 mediates lysosomal sorting

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Involvement of chemokine receptors in breast cancer metastasis

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082612

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Angiogenesis in cancer and other diseases

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8 July 2018

Expression of stromal cell-derived factor 1 and CXCR4 ligand receptor system in pancreatic cancer: a possible role for tumor progression

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Enhancement of experimental metastasis by tumor necrosis factor

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Boswellic acid acetate induces differentiation and apoptosis in highly metastatic melanoma and fibrosarcoma cells.

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Blockade of the Stromal Cell–Derived Factor-1/CXCR4 Axis AttenuatesIn vivoTumor Growth by Inhibiting Angiogenesis in a Vascular Endothelial Growth Factor–Independent Manner

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Cytotoxic action of acetyl-11-keto-beta-boswellic acid (AKBA) on meningioma cells.

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Cytostatic and apoptosis-inducing activity of boswellic acids toward malignant cell lines in vitro

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Keto- and acetyl-keto-boswellic acids inhibit proliferation and induce apoptosis in Hep G2 cells via a caspase-8 dependent pathway

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26 October 2018

Use of the stromal cell-derived factor-1/CXCR4 pathway in prostate cancer metastasis to bone

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https://pubmed.ncbi.nlm.nih.gov/21448932

12 December 2020

based on heuristic

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The chemokine receptor CXCR4 is required for outgrowth of colon carcinoma micrometastases

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https://pubmed.ncbi.nlm.nih.gov/21448932

12 December 2020

based on heuristic

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Acetyl-boswellic acids inhibit lipopolysaccharide-mediated TNF-alpha induction in monocytes by direct interaction with IkappaB kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/21448932

12 December 2020

based on heuristic

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Chemokine receptor CXCR4 expression in breast cancer as a potential predictive marker of isolated tumor cells in bone marrow

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https://pubmed.ncbi.nlm.nih.gov/21448932

12 December 2020

based on heuristic

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CXCR4 chemokine receptor antagonists: perspectives in SCLC

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https://pubmed.ncbi.nlm.nih.gov/21448932

12 December 2020

based on heuristic

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Immunohistochemical evaluation of HER-2/neu expression in pancreatic adenocarcinoma and pancreatic intraepithelial neoplasms

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https://pubmed.ncbi.nlm.nih.gov/21448932

12 December 2020

based on heuristic

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Identifiers

10.1002/IJC.25966

1 reference

Europe PubMed Central

4 August 2017

1 reference

Europe PubMed Central

4 August 2017

1 reference

Europe PubMed Central

4 August 2017

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