Modifying the stereochemistry of an enzyme-catalyzed reaction by directed evolution (Q34867008)

5 August 2017

Modifying the stereochemistry of an enzyme-catalyzed reaction by directed evolution (English)

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5 August 2017

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4

Alan Berry

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Adam Nelson

object named as

Adam Nelson

series ordinal

3

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author name string

Gavin J Williams

series ordinal

1

1 reference

5 August 2017

Silvie Domann

series ordinal

2

1 reference

5 August 2017

language of work or name

English

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publication date

7 March 2003

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full work available at URL

5 August 2017

http://eprints.whiterose.ac.uk/557/

content deliverer

White Rose Research Online

object has role

published version

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http://www.pnas.org/cgi/content/full/100/6/3143

object has role

published version

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published in

Proceedings of the National Academy of Sciences of the United States of America

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5 August 2017

100

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5 August 2017

6

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5 August 2017

3143-3148

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Raster3D Version 2.0. A program for photorealistic molecular graphics

5 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152260

8 July 2018

EVOLUTION OF ALDOLASE

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152260

Structure of tagatose-1,6-bisphosphate aldolase. Insight into chiral discrimination, mechanism, and specificity of class II aldolases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152260

Novel enzyme activities and functional plasticity revealed by recombining highly homologous enzymes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152260

In vitro evolution of beta-glucuronidase into a beta-galactosidase proceeds through non-specific intermediates

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152260

Directed evolution of D-2-keto-3-deoxy-6-phosphogluconate aldolase to new variants for the efficient synthesis of D- and L-sugars

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152260

Inversion of stereospecificity of vanillyl-alcohol oxidase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152260

Exploring substrate binding and discrimination in fructose1, 6-bisphosphate and tagatose 1,6-bisphosphate aldolases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152260

Inverting enantioselectivity by directed evolution of hydantoinase for improved production of L-methionine

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152260

Directed evolution of enantioselective enzymes for organic chemistry

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152260

The crystal structure of Escherichia coli class II fructose-1, 6-bisphosphate aldolase in complex with phosphoglycolohydroxamate reveals details of mechanism and specificity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152260

Directed evolution converts subtilisin E into a functional equivalent of thermitase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152260

Conserved residues in the mechanism of the E. coli Class II FBP-aldolase.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152260

Directed evolution of a thermostable esterase.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152260

Enzyme mediated C-C bond formation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152260

Enhanced degradation of polychlorinated biphenyls by directed evolution of biphenyl dioxygenase.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152260

Improved properties of FLP recombinase evolved by cycling mutagenesis.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152260

Serial increase in the thermal stability of 3-isopropylmalate dehydrogenase from Bacillus subtilis by experimental evolution

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152260

DNA shuffling of a family of genes from diverse species accelerates directed evolution

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152260

The crystal structure of a class II fructose-1,6-bisphosphate aldolase shows a novel binuclear metal-binding active site embedded in a familiar fold

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152260

Novel active site in Escherichia coli fructose 1,6-bisphosphate aldolase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152260

Identification of arginine 331 as an important active site residue in the class II fructose-1,6-bisphosphate aldolase of Escherichia coli

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152260

Identification of zinc-binding ligands in the class II fructose-1,6-bisphosphate aldolase of Escherichia coli

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152260

Rapid evolution of a protein in vitro by DNA shuffling

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152260

The molecular characteristics of yeast aldolase.

8 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0635924100

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0635924100

Directed evolution of an enantioselective lipase

21 January 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152260

26 October 2018

https://api.crossref.org/works/10.1073%2FPNAS.0635924100

Directed evolution of a fungal peroxidase

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=152260

Site-directed mutagenesis of putative substrate-binding residues reveals a mechanism controlling the different stereospecificities of two tropinone reductases

26 October 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0635924100

Functional role of metal ions in a class II aldolase

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0635924100

21 January 2018

Identifiers

DOI

10.1073/PNAS.0635924100

1 reference

Dimensions Publication ID

5 August 2017

0 references

10.1073/PNAS.0635924100

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CORE ID

3242293

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0 references

1 reference

5 August 2017

1 reference