Distinct effects of concomitant Jak2V617F expression and Tet2 loss in mice promote disease progression in myeloproliferative neoplasms (Q34876785)

25281607

5 August 2017

title

Distinct effects of concomitant Jak2V617F expression and Tet2 loss in mice promote disease progression in myeloproliferative neoplasms (English)

1 reference

5 August 2017

11

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4 June 2020

author name string

Edwin Chen

1

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4 June 2020

Rebekka K Schneider

2

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4 June 2020

Lawrence J Breyfogle

3

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4 June 2020

Emily A Rosen

4

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4 June 2020

Luke Poveromo

5

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4 June 2020

Shannon Elf

6

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4 June 2020

Amy Ko

7

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4 June 2020

Kristina Brumme

8

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Ross Levine

9

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4 June 2020

Benjamin L Ebert

10

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4 June 2020

language of work or name

English

0 references

publication date

3 October 2014

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5 August 2017

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4 June 2020

volume

125

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issue

2

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4 June 2020

page(s)

327-335

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Integrated genomic analysis illustrates the central role of JAK-STAT pathway activation in myeloproliferative neoplasm pathogenesis

4 June 2020

cites work

1 reference

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Somatic CALR mutations in myeloproliferative neoplasms with nonmutated JAK2

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Somatic mutations of calreticulin in myeloproliferative neoplasms

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Depletion of Jak2V617F myeloproliferative neoplasm-propagating stem cells by interferon-α in a murine model of polycythemia vera

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Distinct roles for long-term hematopoietic stem cells and erythroid precursor cells in a murine model of Jak2V617F-mediated polycythemia vera

8 July 2018

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Genetic analysis of patients with leukemic transformation of myeloproliferative neoplasms shows recurrent SRSF2 mutations that are associated with adverse outcome

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Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation

8 July 2018

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8 July 2018

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Mouse models of myeloproliferative neoplasms: JAK of all grades

8 July 2018

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Disease burden at the progenitor level is a feature of primary myelofibrosis: a multivariable analysis of 164 JAK2 V617F-positive myeloproliferative neoplasm patients

8 July 2018

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Physiological Jak2V617F expression causes a lethal myeloproliferative neoplasm with differential effects on hematopoietic stem and progenitor cells

8 July 2018

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Novel mutations in the inhibitory adaptor protein LNK drive JAK-STAT signaling in patients with myeloproliferative neoplasms.

8 July 2018

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Pathological interactions between hematopoietic stem cells and their niche revealed by mouse models of primary myelofibrosis

8 July 2018

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Genetic analysis of transforming events that convert chronic myeloproliferative neoplasms to leukemias

8 July 2018

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Mutation in TET2 in myeloid cancers

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TET2 mutations and their clinical correlates in polycythemia vera, essential thrombocythemia and myelofibrosis

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8 July 2018

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26 October 2018

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26 October 2018

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26 October 2018

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26 October 2018

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26 October 2018

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10.1182/BLOOD-2014-04-567024

9 December 2018

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