The in vivo expression of actin/salt-resistant hyperactive DNase I inhibits the development of anti-ssDNA and anti-histone autoantibodies in a murine model of systemic lupus erythematosus (Q34897103)

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English	The in vivo expression of actin/salt-resistant hyperactive DNase I inhibits the development of anti-ssDNA and anti-histone autoantibodies in a murine model of systemic lupus erythematosus	scientific article

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scholarly article

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Europe PubMed Central

5 August 2017

The in vivo expression of actin/salt-resistant hyperactive DNase I inhibits the development of anti-ssDNA and anti-histone autoantibodies in a murine model of systemic lupus erythematosus (English)

1 reference

Europe PubMed Central

5 August 2017

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based on heuristic

inferred from title

systemic lupus erythematosus

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based on heuristic

inferred from title

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based on heuristic

inferred from title

7

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Europe PubMed Central

5 August 2017

8

object named as

Marina Botto

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author name string

Anthony P Manderson

1

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Europe PubMed Central

5 August 2017

Francesco Carlucci

2

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Europe PubMed Central

5 August 2017

Peter J Lachmann

3

1 reference

Europe PubMed Central

5 August 2017

Robert A Lazarus

4

1 reference

Europe PubMed Central

5 August 2017

Richard J Festenstein

5

1 reference

Europe PubMed Central

5 August 2017

H Terence Cook

6

1 reference

Europe PubMed Central

5 August 2017

Marina Botto

8

1 reference

Europe PubMed Central

5 August 2017

publication date

10 April 2006

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Europe PubMed Central

5 August 2017

Arthritis Research and Therapy

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Europe PubMed Central

5 August 2017

8

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Europe PubMed Central

5 August 2017

3

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Europe PubMed Central

5 August 2017

R68

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Europe PubMed Central

5 August 2017

https://scigraph.springernature.com/pub.10.1186/ar1936

0 references

Autoantibody explosion in systemic lupus erythematosus: more than 100 different antibodies found in SLE patients

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8 July 2018

Crystalline desoxyribonuclease; isolation and general properties; spectrophotometric method for the measurement of desoxyribonuclease activity

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526614

8 July 2018

Spontaneous autoimmunity in 129 and C57BL/6 mice-implications for autoimmunity described in gene-targeted mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526614

8 July 2018

Chromatin breakdown during necrosis by serum Dnase1 and the plasminogen system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526614

8 July 2018

Expression pattern of the deoxyribonuclease 1 gene: lessons from the Dnase1 knockout mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526614

8 July 2018

A real-time DNase assay (ReDA) based on PicoGreen fluorescence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526614

8 July 2018

Transglutaminase 2-/- mice reveal a phagocytosis-associated crosstalk between macrophages and apoptotic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526614

8 July 2018

Serum amyloid P component and C-reactive protein opsonize apoptotic cells for phagocytosis through Fcgamma receptors

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526614

8 July 2018

Delayed apoptotic cell clearance and lupus-like autoimmunity in mice lacking the c-mer membrane tyrosine kinase

1 reference

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8 July 2018

Mutation of DNASE1 in people with systemic lupus erythematosus

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526614

8 July 2018

Chromatin-independent binding of serum amyloid P component to apoptotic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526614

8 July 2018

Phagocytosis and clearance of apoptotic cells is mediated by MER.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526614

8 July 2018

Assays for human DNase I activity in biological matrices

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526614

8 July 2018

Engineered properties and assays for human DNase I mutants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526614

8 July 2018

A hierarchical role for classical pathway complement proteins in the clearance of apoptotic cells in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526614

8 July 2018

Features of systemic lupus erythematosus in Dnase1-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526614

8 July 2018

Deficiency in serum immunoglobulin (Ig)M predisposes to development of IgG autoantibodies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526614

8 July 2018

Accelerated development of IgG autoantibodies and autoimmune disease in the absence of secreted IgM.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526614

8 July 2018

Improved potency of hyperactive and actin-resistant human DNase I variants for treatment of cystic fibrosis and systemic lupus erythematosus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526614

8 July 2018

Amyloid deposition is delayed in mice with targeted deletion of the serum amyloid P component gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526614

8 July 2018

Engineering hyperactive variants of human deoxyribonuclease I by altering its functional mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526614

8 July 2018

Ultraviolet light-induced keratinocyte apoptosis: a potential mechanism for the induction of skin lesions and autoantibody production in LE.

1 reference

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8 July 2018

The treatment of systemic lupus erythematosus (SLE) in NZB/W F1 hybrid mice; studies with recombinant murine DNase and with dexamethasone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526614

8 July 2018

Engineering actin-resistant human DNase I for treatment of cystic fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526614

8 July 2018

Nucleosome: a major immunogen for pathogenic autoantibody-inducing T cells of lupus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526614

8 July 2018

Genesis and evolution of antichromatin autoantibodies in murine lupus implicates T-dependent immunization with self antigen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526614

8 July 2018

Anti-nucleosome antibodies complexed to nucleosomal antigens show anti-DNA reactivity and bind to rat glomerular basement membrane in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526614

8 July 2018

Colorimetric determination of DNase I activity with a DNA-methyl green substrate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526614

8 July 2018

Anti-DNA antibodies bind to DNase I.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526614

8 July 2018

Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526614

8 July 2018

Allergic reactions, connective tissue, and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526614

8 July 2018

Serum amyloid P component is the major calcium-dependent specific DNA binding protein of the serum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526614

8 July 2018

Serum amyloid P component binds to cell nuclei in vitro and to in vivo deposits of extracellular chromatin in systemic lupus erythematosus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526614

8 July 2018

Endogenous circulating DNA in systemic lupus erythematosus. Occurrence as multimeric complexes bound to histone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526614

8 July 2018

Subnucleosome structures as substrates in enzyme-linked immunosorbent assays

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526614

8 July 2018

The role of somatic mutation in the pathogenic anti-DNA response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526614

8 July 2018

Binding specificity of the two major DNA-binding proteins in human serum

1 reference

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8 July 2018

Features of systemic lupus erythematosus in mice injected with bacterial lipopolysaccharides: identificantion of circulating DNA and renal localization of DNA-anti-DNA complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526614

8 July 2018

Autoimmunity and glomerulonephritis in mice with targeted deletion of the serum amyloid P component gene: SAP deficiency or strain combination?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526614

26 October 2018

Serum amyloid P component binds to late apoptotic cells and mediates their uptake by monocyte-derived macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526614

26 October 2018

A molecular analysis of the low serum deoxyribonuclease activity in lupus patients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526614

26 October 2018

Accelerated nephrotoxic nephritis is exacerbated in C1q-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526614

26 October 2018

Serum amyloid P component controls chromatin degradation and prevents antinuclear autoimmunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526614

26 October 2018

DNAse treatment does not improve the survival of lupus prone (NZB x NZW)F1 mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526614

26 October 2018

Hyperactivity of human DNase I variants. Dependence on the number of positively charged residues and concentration, length, and environment of DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526614

26 October 2018

Measurement of deoxyribonuclease I (DNase) in the serum and urine of systemic lupus erythematosus (SLE)-prone NZB/NZW mice by a new radial enzyme diffusion assay.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526614

26 October 2018

The relationship of desoxyribonuclease inhibitor levels in human sera to the occurrence of antinuclear antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526614

26 October 2018

Pentraxin-chromatin interactions: serum amyloid P component specifically displaces H1-type histones and solubilizes native long chromatin

1 reference

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26 October 2018

Lupus, DNase and defective disposal of cellular debris

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526614

9 December 2018

Recombinant human Dnase I (rhDNase) in patients with lupus nephritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526614

9 December 2018

Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526614

9 December 2018

Measurement of deoxyribonuclease I activity in human tissues and body fluids by a single radial enzyme-diffusion method

1 reference

https://pubmed.ncbi.nlm.nih.gov/16606442

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mammalian deoxyribonucleases I are classified into three types: pancreas, parotid, and pancreas-parotid (mixed), based on differences in their tissue concentrations

1 reference

https://pubmed.ncbi.nlm.nih.gov/16606442

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma levels of nucleosomes and nucleosome-autoantibody complexes in murine lupus: effects of disease progression and lipopolyssacharide administration

1 reference

https://pubmed.ncbi.nlm.nih.gov/16606442

12 December 2020

based on heuristic

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DNASE I mutation and systemic lupus erythematosus in a Spanish population: comment on the article by Tew et al

1 reference

https://pubmed.ncbi.nlm.nih.gov/16606442

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The expression of plasma nucleosomes in mice undergoing in vivo apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16606442

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The use of fluorometric assays to assess the immune response to DNA in murine systemic lupus erythematosus

1 reference

https://pubmed.ncbi.nlm.nih.gov/16606442

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The relation of deoxyribonuclease inhibitor levels to the occurrence of antinuclear antibodies in NZB-NZW mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/16606442

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The in vitro and in vivo induction of anti-double-stranded DNA antibodies in normal and autoimmune mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/16606442

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nucleosome-restricted antibodies are detected before anti-dsDNA and/or antihistone antibodies in serum of MRL-Mp lpr/lpr and +/+ mice, and are present in kidney eluates of lupus mice with proteinuria

1 reference

https://pubmed.ncbi.nlm.nih.gov/16606442

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Improved version of a human CD2 minigene based vector for T cell-specific expression in transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/16606442

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based on heuristic

inferred from PubMed ID database lookup

Locus control region function and heterochromatin-induced position effect variegation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16606442

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nucleosomes and histones are present in glomerular deposits in human lupus nephritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16606442

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transglutaminase type II is a key element in the regulation of the anti-inflammatory response elicited by apoptotic cell engulfment

1 reference

https://pubmed.ncbi.nlm.nih.gov/16606442

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new ELISA for the detection of double-stranded DNA antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/16606442

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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Europe PubMed Central

5 August 2017

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1 reference

Europe PubMed Central

5 August 2017

1 reference

Europe PubMed Central

5 August 2017

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