MCAF1/AM is involved in Sp1-mediated maintenance of cancer-associated telomerase activity (Q34910264)

5 August 2017

title

MCAF1/AM is involved in Sp1-mediated maintenance of cancer-associated telomerase activity (English)

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5 August 2017

5

Shinjiro Hino

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5 August 2017

Lifeng Liu

1

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5 August 2017

Ko Ishihara

2

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5 August 2017

Takaya Ichimura

3

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5 August 2017

Naoyuki Fujita

4

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5 August 2017

Saori Tomita

6

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5 August 2017

Sugiko Watanabe

7

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5 August 2017

Noriko Saitoh

8

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5 August 2017

Takaaki Ito

9

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5 August 2017

Mitsuyoshi Nakao

10

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5 August 2017

language of work or name

English

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publication date

23 December 2008

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Journal of Biological Chemistry

5 August 2017

published in

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5 August 2017

volume

284

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5 August 2017

issue

8

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5 August 2017

page(s)

5165-5174

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Telomere maintenance mechanisms and cellular immortalization.

5 August 2017

cites work

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Inhibition of human telomerase in immortal human cells leads to progressive telomere shortening and cell death

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Sp1 cooperates with c-Myc to activate transcription of the human telomerase reverse transcriptase gene (hTERT).

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Sp transcription factor family and its role in cancer

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MCAF mediates MBD1-dependent transcriptional repression

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A murine ATFa-associated factor with transcriptional repressing activity

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Transcriptional repression and heterochromatin formation by MBD1 and MCAF/AM family proteins

21 January 2018

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mAM facilitates conversion by ESET of dimethyl to trimethyl lysine 9 of histone H3 to cause transcriptional repression

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A set of proteins interacting with transcription factor Sp1 identified in a two-hybrid screening

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Activation of Sp1-mediated transcription by Rta of Epstein-Barr virus via an interaction with MCAF1.

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Mediator of Transcriptional Regulation

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SYBR Green real-time telomeric repeat amplification protocol for the rapid quantification of telomerase activity

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Dual role of DNA methylation inside and outside of CTCF-binding regions in the transcriptional regulation of the telomerase hTERT gene

21 January 2018

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Creation of human tumour cells with defined genetic elements

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A survey of telomerase activity in human cancer

21 January 2018

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21 January 2018

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Increased copy number of the TERT and TERC telomerase subunit genes in cancer cells

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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P300 plays a role in p16(INK4a) expression and cell cycle arrest.

21 January 2018

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Hypermethylation of the human telomerase catalytic subunit (hTERT) gene correlates with telomerase activity.

21 January 2018

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21 January 2018

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21 January 2018

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Involvement of SUMO modification in MBD1- and MCAF1-mediated heterochromatin formation

21 January 2018

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Telomerase redefined: integrated regulation of hTR and hTERT for telomere maintenance and telomerase activity

21 January 2018

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21 January 2018

The Hallmarks of Cancer

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Sp1 and krüppel-like factor family of transcription factors in cell growth regulation and cancer

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M807098200

1 reference

release_bvm5oqmucfbdxfaxe654ww5xku

5 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/bvm5oqmucfbdxfaxe654ww5xku

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference