Synthetic triterpenoid CDDO prevents the progression and metastasis of prostate cancer in TRAMP mice by inhibiting survival signaling (Q34913859)

5 August 2017

title

Synthetic triterpenoid CDDO prevents the progression and metastasis of prostate cancer in TRAMP mice by inhibiting survival signaling (English)

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5 August 2017

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Dorrah Deeb

1

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5 August 2017

Xiaohua Gao

2

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5 August 2017

Yongbo Liu

3

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5 August 2017

Daniel Jiang

4

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5 August 2017

George W Divine

5

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5 August 2017

Ali S Arbab

6

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5 August 2017

Scott A Dulchavsky

7

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5 August 2017

Subhash C Gautam

8

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5 August 2017

language of work or name

English

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publication date

16 February 2011

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5 August 2017

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5 August 2017

volume

32

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5 August 2017

issue

5

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5 August 2017

page(s)

757-764

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Sulforaphane inhibits prostate carcinogenesis and pulmonary metastasis in TRAMP mice in association with increased cytotoxicity of natural killer cells

5 August 2017

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Oleanane triterpenoid CDDO-Me inhibits growth and induces apoptosis in prostate cancer cells by independently targeting pro-survival Akt and mTOR

8 July 2018

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Garlic constituent diallyl trisulfide prevents development of poorly differentiated prostate cancer and pulmonary metastasis multiplicity in TRAMP mice

8 July 2018

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CDDO-Me inhibits proliferation, induces apoptosis, down-regulates Akt, mTOR, NF-kappaB and NF-kappaB-regulated antiapoptotic and proangiogenic proteins in TRAMP prostate cancer cells

8 July 2018

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CDDO-me induces apoptosis and inhibits Akt, mTOR and NF-kappaB signaling proteins in prostate cancer cells

8 July 2018

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The synthetic triterpenoids CDDO-methyl ester and CDDO-ethyl amide prevent lung cancer induced by vinyl carbamate in A/J mice

8 July 2018

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Synthetic triterpenoids inhibit growth and induce apoptosis in human glioblastoma and neuroblastoma cells through inhibition of prosurvival Akt, NF-kappaB and Notch1 signaling

8 July 2018

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8 July 2018

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A synthetic triterpenoid, CDDO-Me, inhibits IkappaBalpha kinase and enhances apoptosis induced by TNF and chemotherapeutic agents through down-regulation of expression of nuclear factor kappaB-regulated gene products in human leukemic cells

8 July 2018

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2-Cyano-3,12-dioxoolean-1,9-dien-28-oic acid and related compounds inhibit growth of colon cancer cells through peroxisome proliferator-activated receptor gamma-dependent and -independent pathways

8 July 2018

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The synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid induces caspase-dependent and -independent apoptosis in acute myelogenous leukemia

8 July 2018

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8 July 2018

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Inhibition of prostate carcinogenesis in TRAMP mice by oral infusion of green tea polyphenols

8 July 2018

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Anti-allergic and anti-inflammatory triterpenes from the herb of Prunella vulgaris

8 July 2018

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The transcription factor NF-kappaB: control of oncogenesis and cancer therapy resistance

8 July 2018

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Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

8 July 2018

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Novel triterpenoids suppress inducible nitric oxide synthase (iNOS) and inducible cyclooxygenase (COX-2) in mouse macrophages

8 July 2018

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Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

8 July 2018

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Metastatic prostate cancer in a transgenic mouse

8 July 2018

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Fruit, vegetables, and cancer prevention: a review of the epidemiological evidence

8 July 2018

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The novel triterpenoid C-28 methyl ester of 2-cyano-3, 12-dioxoolen-1, 9-dien-28-oic acid inhibits metastatic murine breast tumor growth through inactivation of STAT3 signaling.

8 July 2018

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Potent protection against aflatoxin-induced tumorigenesis through induction of Nrf2-regulated pathways by the triterpenoid 1-[2-cyano-3-,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole

26 October 2018

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Chemoprevention of human prostate cancer by oral administration of green tea catechins in volunteers with high-grade prostate intraepithelial neoplasia: a preliminary report from a one-year proof-of-principle study

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086702

The novel triterpenoid CDDO-Me suppresses MAPK pathways and promotes p38 activation in acute myeloid leukemia cells

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086702

A pilot clinical study of short-term isoflavone supplements in breast cancer patients

26 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086702

The novel triterpenoid CDDO and its derivatives induce apoptosis by disruption of intracellular redox balance

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086702

Synthetic triterpenoids enhance transforming growth factor beta/Smad signaling

26 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086702

Chemopreventive efficacy and pharmacokinetics of curcumin in the min/+ mouse, a model of familial adenomatous polyposis.

26 October 2018

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Novel triterpenoid CDDO-Me is a potent inducer of apoptosis and differentiation in acute myelogenous leukemia

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086702

Genistein in the diet reduces the incidence of poorly differentiated prostatic adenocarcinoma in transgenic mice (TRAMP).

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086702

The novel triterpenoid CDDO induces apoptosis and differentiation of human osteosarcoma cells by a caspase-8 dependent mechanism

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086702

Inhibition of skin tumorigenesis by rosemary and its constituents carnosol and ursolic acid.

26 October 2018

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Novel synthetic oleanane triterpenoids: a series of highly active inhibitors of nitric oxide production in mouse macrophages

26 October 2018

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12 December 2020

Inhibition of the tumor-promoting action of 12-O-tetradecanoylphorbol-13-acetate by some oleanane-type triterpenoid compounds

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12 December 2020

Pathologic progression of autochthonous prostate cancer in the TRAMP model

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12 December 2020

Pathobiology of autochthonous prostate cancer in a pre‐clinical transgenic mouse model

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12 December 2020

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12 December 2020

Dietary flavonoid and cancer prevention: evidence and potential mechanism

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12 December 2020

Design and synthesis of 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid, a novel and highly active inhibitor of nitric oxide production in mouse macrophages

1 reference

12 December 2020

Constitutive activation of P I3 K-Akt and NF-kappaB during prostate cancer progression in autochthonous transgenic mouse model

1 reference

12 December 2020

Identifiers

DOI

10.1093/CARCIN/BGR030

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5 August 2017

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5 August 2017

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