Molecular determinants of metalloproteinase substrate specificity: matrix metalloproteinase substrate binding domains, modules, and exosites (Q34920476)

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English	Molecular determinants of metalloproteinase substrate specificity: matrix metalloproteinase substrate binding domains, modules, and exosites	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

5 August 2017

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Europe PubMed Central

Molecular determinants of metalloproteinase substrate specificity: matrix metalloproteinase substrate binding domains, modules, and exosites (English)

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Europe PubMed Central

PubMed publication ID

5 August 2017

Christopher Overall

1

object named as

Christopher M Overall

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Europe PubMed Central

PubMed publication ID

5 August 2017

publication date

1 September 2002

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Europe PubMed Central

PubMed publication ID

5 August 2017

Molecular Biotechnology

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Europe PubMed Central

PubMed publication ID

5 August 2017

22

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

51-86

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

https://scigraph.springernature.com/pub.10.1385/mb:22:1:051

0 references

Binding of tissue inhibitor of metalloproteinases 2 to two distinct sites on human 72-kDa gelatinase. Identification of a stabilization site

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Understanding the P1' specificity of the matrix metalloproteinases: effect of S1' pocket mutations in matrilysin and stromelysin-1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure of human neutrophil collagenase reveals large S1' specificity pocket

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel matrix metalloproteinase gene (XMMP) encoding vitronectin-like motifs is transiently expressed in Xenopus laevis early embryo development

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Matrix metalloproteinase activity inactivates the CXC chemokine stromal cell-derived factor-1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure and distribution of modules in extracellular proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An internal cysteine plays a role in the maintenance of the latency of human fibroblast collagenase.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The involvement of the fibronectin type II-like modules of human gelatinase A in cell surface localization and activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Independent regulation of collagenase, 72-kDa progelatinase, and metalloendoproteinase inhibitor expression in human fibroblasts by transforming growth factor-beta

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

2.0 A crystal structure of a four-domain segment of human fibronectin encompassing the RGD loop and synergy region

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure of the catalytic domain of fibroblast collagenase complexed with an inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The X-ray crystal structure of the catalytic domain of human neutrophil collagenase inhibited by a substrate analogue reveals the essentials for catalysis and specificity

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of tissue inhibitor of matrix metalloproteinase expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional and post-transcriptional regulation of 72-kDa gelatinase/type IV collagenase by transforming growth factor-beta 1 in human fibroblasts. Comparisons with collagenase and tissue inhibitor of matrix metalloproteinase gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Three-dimensional type I collagen lattices induce coordinate expression of matrix metalloproteinases MT1-MMP and MMP-2 in microvascular endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signal transduction through the fibronectin receptor induces collagenase and stromelysin gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characteristics of the action of human skin fibroblast collagenase on fibrillar collagen

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

H-ras oncogene-transformed human bronchial epithelial cells (TBE-1) secrete a single metalloprotease capable of degrading basement membrane collagen

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alanine scanning mutagenesis and functional analysis of the fibronectin-like collagen-binding domain from human 92-kDa type IV collagenase.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Further localization of the gelatin-binding determinants within fibronectin. Active fragments devoid of type II homologous repeat modules

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure of full-length porcine synovial collagenase reveals a C-terminal domain containing a calcium-linked, four-bladed beta-propeller

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sequence specificity of human skin fibroblast collagenase. Evidence for the role of collagen structure in determining the collagenase cleavage site

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human fibroblast stromelysin catalytic domain: expression, purification, and characterization of a C-terminally truncated form

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure of the catalytic domain of human fibroblast collagenase complexed with an inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NMR of modular proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The collagen-binding site of type-II units of bovine seminal fluid protein PDC-109 and fibronectin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The activity of the tissue inhibitors of metalloproteinases is regulated by C-terminal domain interactions: a kinetic analysis of the inhibition of gelatinase A.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Contribution of hydrogen bonding to the conformational stability of ribonuclease T1

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The gelatin-binding site of human 72 kDa type IV collagenase (gelatinase A).

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteolytic processing of membrane-type-1 matrix metalloproteinase is associated with gelatinase A activation at the cell surface

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Matrix metalloproteinases in periodontal tissue remodelling

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exons--original building blocks of proteins?

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning and characterization of human MMP-23, a new matrix metalloproteinase predominantly expressed in reproductive tissues and lacking conserved domains in other family members

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of the C-terminal domain of human collagenase-3 (MMP-13) in the activation of procollagenase-3, substrate specificity, and tissue inhibitor of metalloproteinase interaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Domain structure and interactions of the type I and type II modules in the gelatin-binding region of fibronectin. All six modules are independently folded

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of the C-terminal domain in collagenase and stromelysin specificity

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammation dampened by gelatinase A cleavage of monocyte chemoattractant protein-3

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cancer cell-associated fibronectin induces release of matrix metalloproteinase-2 from normal fibroblasts.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The structural basis for the elastolytic activity of the 92-kDa and 72-kDa gelatinases. Role of the fibronectin type II-like repeats

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The TIMP2 membrane type 1 metalloproteinase "receptor" regulates the concentration and efficient activation of progelatinase A. A kinetic study

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human progelatinase A can be activated by autolysis at a rate that is concentration-dependent and enhanced by heparin bound to the C-terminal domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative sequence specificities of human 72- and 92-kDa gelatinases (type IV collagenases) and PUMP (matrilysin)

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Collagen-binding recombinant fibronectin fragments containing type II domains.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The hemopexin-like domain (C domain) of human gelatinase A (matrix metalloproteinase-2) requires Ca2+ for fibronectin and heparin binding. Binding properties of recombinant gelatinase A C domain to extracellular matrix and basement membrane componen

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Matrix metalloproteinase-2 is an interstitial collagenase. Inhibitor-free enzyme catalyzes the cleavage of collagen fibrils and soluble native type I collagen generating the specific 3/4- and 1/4-length fragments.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Astacins, serralysins, snake venom and matrix metalloproteinases exhibit identical zinc-binding environments (HEXXHXXGXXH and Met-turn) and topologies and should be grouped into a common family, the 'metzincins'

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evolutionary families of metallopeptidases

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin alpha v beta 3.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation and characterization of A peptide containing the site of cleavage of the chick skin collagen α1[I] chain by animal collagenases

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the peptide substrate specificities of interstitial collagenase and 92-kDa gelatinase. Implications for substrate optimization

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exon shuffling and other ways of module exchange

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A helping hand for collagenases: the haemopexin-like domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assessment of the role of the fibronectin-like domain of gelatinase A by analysis of a deletion mutant.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The 72 kDa type IV collagenase is modulated via differential expression of alpha v beta 3 and alpha 5 beta 1 integrins during human melanoma cell invasion.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure-function relationship of human neutrophil collagenase: identification of regions responsible for substrate specificity and general proteinase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure of human pro-matrix metalloproteinase-2: activation mechanism revealed

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The C-terminal domain of 72 kDa gelatinase A is not required for catalysis, but is essential for membrane activation and modulates interactions with tissue inhibitors of metalloproteinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characteristics of 92 kDa type IV collagenase/gelatinase produced by granulocytic leukemia cells: structure, expression of cDNA in E. coli and enzymic properties

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel metalloproteinase gene specifically expressed in stromal cells of breast carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Crystal structure of the haemopexin-like C-terminal domain of gelatinase A

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The collagenase gene family in humans consists of at least four members

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Concanavalin A produces a matrix-degradative phenotype in human fibroblasts. Induction and endogenous activation of collagenase, 72-kDa gelatinase, and Pump-1 is accompanied by the suppression of the tissue inhibitor of matrix metalloproteinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A myoglobin variant with a polar substitution in a conserved hydrophobic cluster in the heme binding pocket

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Membrane type 1 matrix metalloproteinase digests interstitial collagens and other extracellular matrix macromolecules

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutational analysis of residues in and around the active site of human fibroblast-type collagenase

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of the tissue inhibitor of metalloproteinases-2 (TIMP-2) binding site on the hemopexin carboxyl domain of human gelatinase A by site-directed mutagenesis. The hierarchical role in binding TIMP-2 of the unique cationic clusters of hemo

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification of recombinant human prostromelysin. Studies on heat activation to give high-Mr and low-Mr active forms, and a comparison of recombinant with natural stromelysin activities

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human skin fibroblast collagenase. Assessment of activation energy and deuterium isotope effect with collagenous substrates

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exons encode protein functional units

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fragments of human fibroblast collagenase. Purification and characterization

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of membrane-type matrix metalloproteinase-1 expression by growth factors and phorbol 12-myristate 13-acetate.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reconstructed 19 kDa catalytic domain of gelatinase A is an active proteinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The helping hand of collagenase-3 (MMP-13): 2.7 A crystal structure of its C-terminal haemopexin-like domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transmembrane-deletion mutants of the membrane-type matrix metalloproteinase-1 process progelatinase A and express intrinsic matrix-degrading activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tissue inhibitor of metalloproteinases-4 inhibits but does not support the activation of gelatinase A via efficient inhibition of membrane type 1-matrix metalloproteinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mapping the collagen-binding site of human fibronectin by expression in Escherichia coli

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Matrix metalloproteinases: structures, evolution, and diversification

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of the contribution of the hinge region of human neutrophil collagenase (HNC, MMP-8) to stability and collagenolytic activity by alanine scanning mutagenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Collagen/collagenase interaction: does the enzyme mimic the conformation of its own substrate?

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The soluble catalytic domain of membrane type 1 matrix metalloproteinase cleaves the propeptide of progelatinase A and initiates autoproteolytic activation. Regulation by TIMP-2 and TIMP-3.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The C-terminal (haemopexin-like) domain structure of human gelatinase A (MMP2): structural implications for its function

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The fibronectin-like domain is required for the type V and XI collagenolytic activity of gelatinase B.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Furin-dependent intracellular activation of the human stromelysin-3 zymogen

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Collagen binding site in collagenase can be determined using the concept of sense-antisense peptide interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sequence specificities of human fibroblast and neutrophil collagenases

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Membrane associated matrix metalloproteinases in metastasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of cell surface activation of 72-kDa type IV collagenase. Isolation of the activated form of the membrane metalloprotease

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tissue inhibitor of metalloproteinase (TIMP-2). A new member of the metalloproteinase inhibitor family

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

How big is the universe of exons?

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural properties of matrix metalloproteinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Implication of collagen type I-induced membrane-type 1-matrix metalloproteinase expression and matrix metalloproteinase-2 activation in the metastatic progression of breast carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple modes of activation of latent human fibroblast collagenase: evidence for the role of a Cys73 active-site zinc complex in latency and a "cysteine switch" mechanism for activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of zinc-binding- and hemopexin domain-encoded sequences in the substrate specificity of collagenase and stromelysin-2 as revealed by chimeric proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for the involvement of type II domains in collagen binding by 72 kDa type IV procollagenase

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

On the structure and chromosome location of the 72- and 92-kDa human type IV collagenase genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Domain interactions in the gelatinase A.TIMP-2.MT1-MMP activation complex. The ectodomain of the 44-kDa form of membrane type-1 matrix metalloproteinase does not modulate gelatinase A activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extracellular matrix binding properties of recombinant fibronectin type II-like modules of human 72-kDa gelatinase/type IV collagenase. High affinity binding to native type I collagen but not native type IV collagen

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SV40-transformed human lung fibroblasts secrete a 92-kDa type IV collagenase which is identical to that secreted by normal human macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of the role of the COOH-terminal domain in the activation, proteolytic activity, and tissue inhibitor of metalloproteinase interactions of gelatinase B

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High affinity binding of latent matrix metalloproteinase-9 to the alpha2(IV) chain of collagen IV.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sea urchin hatching enzyme (envelysin): cDNA cloning and deprivation of protein substrate specificity by autolytic degradation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Why genes in pieces?

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific, high affinity binding of tissue inhibitor of metalloproteinases-4 (TIMP-4) to the COOH-terminal hemopexin-like domain of human gelatinase A. TIMP-4 binds progelatinase A and the COOH-terminal domain in a similar manner to TIMP-2

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Binding of gelatinases A and B to type-I collagen and other matrix components

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1385/MB:22:1:051

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Dimensions Publication ID

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

ResearchGate publication ID

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