STAT6 mediates interleukin-4 growth inhibition in human breast cancer cells (Q34929161)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12082548%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

title

STAT6 mediates interleukin-4 growth inhibition in human breast cancer cells (English)

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10 November 2019

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3

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10 November 2019

author name string

Jennifer L Gooch

series ordinal

1

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10 November 2019

Barbara Christy

series ordinal

2

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10 November 2019

publication date

1 July 2002

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10 November 2019

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10 November 2019

volume

4

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10 November 2019

issue

4

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10 November 2019

page(s)

324-331

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Insulin-like growth factor I-induced degradation of insulin receptor substrate 1 is mediated by the 26S proteasome and blocked by phosphatidylinositol 3'-kinase inhibition

10 November 2019

cites work

1 reference

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Extracellular signal-regulated kinase (ERK) interacts with signal transducer and activator of transcription (STAT) 5a

8 July 2018

1 reference

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Interleukin 4 inhibits growth and induces apoptosis in human breast cancer cells.

8 July 2018

1 reference

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Stat proteins control lymphocyte proliferation by regulating p27Kip1 expression

8 July 2018

1 reference

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A phase II study of recombinant human interleukin-4 for advanced or recurrent non-small cell lung cancer

8 July 2018

1 reference

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Identification of a STAT6 domain required for IL-4-induced activation of transcription

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1531710

Insulin receptor substrate-2 is the major 170-kDa protein phosphorylated on tyrosine in response to cytokines in murine lymphohemopoietic cells

8 July 2018

1 reference

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IL-4 protects cells from apoptosis via the insulin receptor substrate pathway and a second independent signaling pathway

8 July 2018

1 reference

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Interleukin-4 and interleukin-13 inhibit estrogen-induced breast cancer cell proliferation and stimulate GCDFP-15 expression in human breast cancer cells

8 July 2018

1 reference

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Requirements for interleukin-4-induced gene expression and functional characterization of Stat6

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1531710

Growth inhibition signalled through the interleukin-4/interleukin-13 receptor complex is associated with tyrosine phosphorylation of insulin receptor substrate-1.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1531710

Suppression of interleukin-1 beta-converting enzyme-mediated cell death by insulin-like growth factor

8 July 2018

1 reference

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Expression of high affinity interleukin-4 receptors on human renal cell carcinoma cells and inhibition of tumor cell growth in vitro by interleukin-4.

8 July 2018

1 reference

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Interleukin 4 targeting of immunoglobulin heavy chain class-switch recombination

8 July 2018

1 reference

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LR1 regulates c-myc transcription in B-cell lymphomas

8 July 2018

1 reference

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Characterization of the interleukin-4 nuclear activated factor/STAT and its activation independent of the insulin receptor substrate proteins

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1531710

How cytokines control immunoglobulin class switching.

8 July 2018

1 reference

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Cytokine receptor signalling

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1531710

Interleukin 4 signals through two related pathways

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1531710

Multiple cytokines activate phosphatidylinositol 3-kinase in hemopoietic cells. Association of the enzyme with various tyrosine-phosphorylated proteins.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1531710

Murine interleukin-4 displays potent anti-tumor activity in vivo

8 July 2018

1 reference

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Tumour-associated upregulation of the IL-4 receptor complex.

8 July 2018

1 reference

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Prognostic significance of insulin-like growth factor 1 receptors in human breast cancer

8 July 2018

1 reference

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Interleukin-4: a prototypic immunoregulatory lymphokine

8 July 2018

1 reference

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Treatment of established renal cancer by tumor cells engineered to secrete interleukin-4.

8 July 2018

1 reference

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Recombinant human interleukin 4 (IL-4) given as daily subcutaneous injections – a phase I dose toxicity trial

8 July 2018

1 reference

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IL-4 induces serine phosphorylation of the STAT6 transactivation domain in B lymphocytes.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1531710

Expression of the insulin-like growth factor I receptor C terminus as a myristylated protein leads to induction of apoptosis in tumor cells.

26 October 2018

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Recombinant human interleukin 4 has antiproliferative activity on human tumor cell lines derived from epithelial and nonepithelial histologies.

26 October 2018

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Insulin Receptor Substrate-1 is the Predominant Signaling Molecule Activated by Insulin-like Growth Factor-I, Insulin, and Interleukin-4 in Estrogen Receptor-positive Human Breast Cancer Cells

26 October 2018

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12 December 2020

Granulocyte-macrophage colony-stimulating factor-activated signaling pathways in human neutrophils. Involvement of Jak2 in the stimulation of phosphatidylinositol 3-kinase

1 reference

12 December 2020

The functional synergy between IL-12 and IL-2 involves p38 mitogen-activated protein kinase and is associated with the augmentation of STAT serine phosphorylation

1 reference

12 December 2020

Enhancement of Insulin-Like Growth Factor Signaling in Human Breast Cancer: Estrogen Regulation of Insulin Receptor Substrate-1 Expressionin Vitroandin Vivo

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12 December 2020

Multiple signaling pathways mediate interleukin-4-induced 3beta-hydroxysteroid dehydrogenase/delta5-delta4 isomerase type 1 gene expression in human breast cancer cells

1 reference

12 December 2020

Interleukin-4 mediates cell growth inhibition through activation of Stat1

1 reference

12 December 2020

The role of p21 in interferon gamma-mediated growth inhibition of human breast cancer cells

1 reference

12 December 2020

Interleukin 4 receptor expression on human lung tumors and normal lung

1 reference

12 December 2020

Expression of high-affinity interleukin 4 receptors on murine sarcoma cells and receptor-mediated cytotoxicity of tumor cells to chimeric protein between interleukin 4 and Pseudomonas exotoxin

1 reference

12 December 2020

Inhibition of colon and breast carcinoma cell growth by interleukin-4

1 reference

12 December 2020

Optimized assays for quantifying transient expressions of co-transfected beta-galactosidase and CAT reporter genes

1 reference

12 December 2020

Expression of high-affinity IL-4 receptors on human melanoma, ovarian and breast carcinoma cells

1 reference

12 December 2020

Induction of germ-line gamma 1 and epsilon Ig gene expression in murine B cells. IL-4 and the CD40 ligand-CD40 interaction provide distinct but synergistic signals

1 reference

12 December 2020

Identifiers

DOI

10.1038/SJ.NEO.7900248

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12082548%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12082548%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

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