In vivo opioid receptor heteromerization: where do we stand? (Q34939677)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24666391%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

title

In vivo opioid receptor heteromerization: where do we stand? (English)

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12 March 2020

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1

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12 March 2020

author name string

D Massotte

series ordinal

1

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PubMed publication ID

24666391

5 August 2017

language of work or name

English

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publication date

1 July 2014

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British Journal of Pharmacology

12 March 2020

published in

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12 March 2020

volume

172

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12 March 2020

issue

2

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12 March 2020

page(s)

420-434

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A mu-delta opioid receptor brain atlas reveals neuronal co-occurrence in subcortical networks

12 March 2020

cites work

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Structure of the δ-opioid receptor bound to naltrindole

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Receptor heteromerization expands the repertoire of cannabinoid signaling in rodent neurons

8 July 2018

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Current research on opioid receptor function

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Spinal synthesis of estrogen and concomitant signaling by membrane estrogen receptors regulate spinal κ- and μ-opioid receptor heterodimerization and female-specific spinal morphine antinociception

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8 July 2018

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8 July 2018

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8 July 2018

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Making structural sense of dimerization interfaces of delta opioid receptor homodimers

8 July 2018

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Exploring a role for heteromerization in GPCR signalling specificity

8 July 2018

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8 July 2018

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Formation of mu-/kappa-opioid receptor heterodimer is sex-dependent and mediates female-specific opioid analgesia

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Subcellular imaging of dynamic protein interactions by bioluminescence resonance energy transfer

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Receptor heterodimerization leads to a switch in signaling: beta-arrestin2-mediated ERK activation by mu-delta opioid receptor heterodimers

8 July 2018

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8 July 2018

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Trafficking of delta-opioid receptors and other G-protein-coupled receptors: implications for pain and analgesia

8 July 2018

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Knockin mice expressing fluorescent delta-opioid receptors uncover G protein-coupled receptor dynamics in vivo

8 July 2018

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Mu-delta opioid receptor functional interaction: Insight using receptor-G protein fusions

8 July 2018

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mu opioid and CB1 cannabinoid receptor interactions: reciprocal inhibition of receptor signaling and neuritogenesis

8 July 2018

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Role of delivery and trafficking of delta-opioid peptide receptors in opioid analgesia and tolerance

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Opioid-induced tolerance and dependence in mice is modulated by the distance between pharmacophores in a bivalent ligand series

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Current methods used to investigate G protein coupled receptor oligomerisation

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8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292957

Interaction of bivalent ligand KDN21 with heterodimeric delta-kappa opioid receptors in human embryonic kidney 293 cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292957

A heterodimer-selective agonist shows in vivo relevance of G protein-coupled receptor dimers

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292957

A bivalent ligand (KDAN-18) containing delta-antagonist and kappa-agonist pharmacophores bridges delta2 and kappa1 opioid receptor phenotypes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292957

Heterodimerization of opioid receptor-like 1 and mu-opioid receptors impairs the potency of micro receptor agonist

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292957

Opioids: cellular mechanisms of tolerance and physical dependence

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292957

Heterodimerization of mu- and delta-opioid receptors occurs at the cell surface only and requires receptor-G protein interactions.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292957

A bivalent ligand (KDN-21) reveals spinal delta and kappa opioid receptors are organized as heterodimers that give rise to delta(1) and kappa(2) phenotypes. Selective targeting of delta-kappa heterodimers

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292957

A role for heterodimerization of mu and delta opiate receptors in enhancing morphine analgesia

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292957

Homo- and hetero-oligomeric interactions between G-protein-coupled receptors in living cells monitored by two variants of bioluminescence resonance energy transfer (BRET): hetero-oligomers between receptor subtypes form more efficiently than between

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292957

Oligomerization of G-protein-coupled receptors shown by selective co-immunoprecipitation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292957

Heterodimerization of mu and delta opioid receptors: A role in opiate synergy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292957

G-protein-coupled receptor heterodimerization modulates receptor function

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292957

GABA(B) receptors function as a heteromeric assembly of the subunits GABA(B)R1 and GABA(B)R2.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292957

Morphine activates opioid receptors without causing their rapid internalization

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292957

Blockade of alpha 2-adrenoceptors increases opioid mu-receptor-mediated inhibition of the firing rate of rat locus coeruleus neurones

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292957

ORL1 receptor-mediated internalization of N-type calcium channels

8 July 2018

1 reference

Consequences of opioid receptor mutation on actions of univalent and bivalent kappa and delta ligands

21 January 2018

1 reference

Heterooligomerization of human dopamine receptor 2 and somatostatin receptor 2 Co-immunoprecipitation and fluorescence resonance energy transfer analysis.

21 January 2018

1 reference

Agonist-independent modulation of N-type calcium channels by ORL1 receptors.

21 January 2018

1 reference

Differentiation of mouse embryonic stem cells into a defined neuronal lineage

21 January 2018

1 reference

Opioid agonists have different efficacy profiles for G protein activation, rapid desensitization, and endocytosis of mu-opioid receptors

21 January 2018

1 reference

Opioid receptor random mutagenesis reveals a mechanism for G protein-coupled receptor activation

21 January 2018

1 reference

Oligomerization of mu- and delta-opioid receptors. Generation of novel functional properties

21 January 2018

1 reference

Trafficking of preassembled opioid mu-delta heterooligomer-Gz signaling complexes to the plasma membrane: coregulation by agonists

21 January 2018

1 reference

Facilitation of μ-opioid receptor activity by preventing δ-opioid receptor-mediated codegradation.

21 January 2018

1 reference

Mu and delta opioid receptor immunoreactivity and mu receptor regulation in brainstem cells cultured from late fetal and early postnatal rats

21 January 2018

1 reference

Sexually dimorphic recruitment of spinal opioid analgesic pathways by the spinal application of morphine

21 January 2018

1 reference

Computational study of the heterodimerization between mu and delta receptors.

21 January 2018

1 reference

Promiscuous coupling at receptor-Galpha fusion proteins. The receptor of one covalent complex interacts with the alpha-subunit of another

21 January 2018

1 reference

Modulation of neuronal CXCR4 by the micro-opioid agonist DAMGO.

21 January 2018

1 reference

Developmental potential of defined neural progenitors derived from mouse embryonic stem cells

21 January 2018

1 reference

The delta agonists DPDPE and deltorphin II recruit predominantly mu receptors to produce thermal analgesia: a parallel study of mu, delta and combinatorial opioid receptor knockout mice

21 January 2018

1 reference

Subtractive immunization: a tool for the generation of discriminatory antibodies to proteins of similar sequence

21 January 2018

1 reference

Evidence that nor-binaltorphimine can function as an antagonist at multiple opioid receptor subtypes

21 January 2018

1 reference

Alpha-2-adrenergic and opioid receptor additivity in rat locus coeruleus neurons

21 January 2018

1 reference

Retention of supraspinal delta-like analgesia and loss of morphine tolerance in delta opioid receptor knockout mice

21 January 2018

1 reference

Antidepressant-like and anxiolytic-like effects following activation of the μ-δ opioid receptor heteromer in the nucleus accumbens

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292957

Regulation of delta-opioid receptor trafficking via mu-opioid receptor stimulation: evidence from mu-opioid receptor knock-out mice.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292957

Morphine acutely regulates opioid receptor trafficking selectively in dendrites of nucleus accumbens neurons.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292957

Genetic dissociation of opiate tolerance and physical dependence in delta-opioid receptor-1 and preproenkephalin knock-out mice.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292957

Prolonged morphine treatment targets delta opioid receptors to neuronal plasma membranes and enhances delta-mediated antinociception.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292957

Ultrastructural localization of the CB1 cannabinoid receptor in mu-opioid receptor patches of the rat Caudate putamen nucleus.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292957

Selective blockage of delta opioid receptors prevents the development of morphine tolerance and dependence in mice

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4292957

Prediction of heterodimerization interfaces of G-protein coupled receptors with a new subtractive correlated mutation method

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24666391

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1111/BPH.12702

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24666391%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24666391%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

PubMed publication ID

24666391

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24666391%20AND%20SRC:MED&resulttype=core&format=json