Impaired clearance of apoptotic cardiocytes is linked to anti-SSA/Ro and -SSB/La antibodies in the pathogenesis of congenital heart block. (Q34945212)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16906225%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

title

Impaired clearance of apoptotic cardiocytes is linked to anti-SSA/Ro and -SSB/La antibodies in the pathogenesis of congenital heart block (English)

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28 December 2019

0 references

0 references

1 reference

5

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28 December 2019

Jill P Buyon

7

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28 December 2019

author name string

Robert M Clancy

1

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28 December 2019

Petra J Neufing

2

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28 December 2019

Ping Zheng

3

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28 December 2019

Marguerita O'Mahony

4

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28 December 2019

Tom P Gordon

6

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28 December 2019

language of work or name

English

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publication date

10 August 2006

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Journal of Clinical Investigation

28 December 2019

published in

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28 December 2019

volume

116

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28 December 2019

issue

9

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28 December 2019

page(s)

2413-2422

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Anti-idiotype-mediated epitope spreading and diminished phagocytosis by a human monoclonal antibody recognizing late-stage apoptotic cells

28 December 2019

cites work

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Ro/SSA autoantibodies directly bind cardiomyocytes, disturb calcium homeostasis, and mediate congenital heart block

8 July 2018

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8 July 2018

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Subcellular redistribution of la/SSB autoantigen during physiologic apoptosis in the fetal mouse heart and conduction system: a clue to the pathogenesis of congenital heart block

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Apoptotic cell removal

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Phagocyte receptors for apoptotic cells: recognition, uptake, and consequences

8 July 2018

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Corpse clearance defines the meaning of cell death

8 July 2018

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A receptor for phosphatidylserine-specific clearance of apoptotic cells

8 July 2018

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CD14-dependent clearance of apoptotic cells: relevance to the immune system.

8 July 2018

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mRNA and protein expression of SSA/Ro and SSB/La in human fetal cardiac myocytes cultured using a novel application of the Langendorff procedure

8 July 2018

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Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner

8 July 2018

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Serum and immunoglobulin G from the mother of a child with congenital heart block induce conduction abnormalities and inhibit L-type calcium channels in a rat heart model.

8 July 2018

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Fas/Fas ligand interactions are involved in ultraviolet-B-induced human lymphocyte apoptosis

8 July 2018

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8 July 2018

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Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF

8 July 2018

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Caspases are activated in a branched protease cascade and control distinct downstream processes in Fas-induced apoptosis

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Immunohistologic evidence supports apoptosis, IgG deposition, and novel macrophage/fibroblast crosstalk in the pathologic cascade leading to congenital heart block

26 October 2018

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26 October 2018

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Transdifferentiation of cardiac fibroblasts, a fetal factor in anti-SSA/Ro-SSB/La antibody-mediated congenital heart block

26 October 2018

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Anti-La/SSB antibodies transported across the placenta bind apoptotic cells in fetal organs targeted in neonatal lupus.

26 October 2018

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Mesenchymal cells engulf and clear apoptotic footplate cells in macrophageless PU.1 null mouse embryos.

26 October 2018

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Autoimmune-associated congenital heart block: demographics, mortality, morbidity and recurrence rates obtained from a national neonatal lupus registry

26 October 2018

1 reference

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Induction of antibodies reactive with SSA/Ro-SSB/La and development of congenital heart block in a murine model

26 October 2018

1 reference

12 December 2020

Anti-SSA/Ro and anti-SSB/La autoantibodies bind the surface of apoptotic fetal cardiocytes and promote secretion of TNF-alpha by macrophages

1 reference

12 December 2020

Does the cellular localization of antigens in or on apoptotic blebs influence the pathogenicity or benefit of cognate antibodies? Comment on the article by Dieudé et al

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12 December 2020

Fc gamma RIIa is expressed on natural IFN-alpha-producing cells (plasmacytoid dendritic cells) and is required for the IFN-alpha production induced by apoptotic cells combined with lupus IgG

1 reference

12 December 2020

Clearance of apoptotic cells: TGF-beta in the balance between inflammation and fibrosis

1 reference

12 December 2020

Intravenous immunoglobulin and placental transport of anti-Ro/La antibodies: comment on the letter by Kaaja and Julkunen

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12 December 2020

Molecular characterization and cloning of the 52 kDa SS-A/Ro protein

1 reference

12 December 2020

Accessibility of SSA/Ro and SSB/La antigens to maternal autoantibodies in apoptotic human fetal cardiac myocytes

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12 December 2020

Exposure and binding of selected immunodominant La/SSB epitopes on human apoptotic cells

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12 December 2020

Accumulation of apoptotic cells in the epidermis of patients with cutaneous lupus erythematosus after ultraviolet irradiation

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12 December 2020

Identifiers

DOI

10.1172/JCI27803

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16906225%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16906225%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

1 reference