Mechanisms underlying nitrate-induced endothelial dysfunction: insight from experimental and clinical studies (Q34963294)

5 August 2017

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title

Mechanisms underlying nitrate-induced endothelial dysfunction: insight from experimental and clinical studies (English)

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5 August 2017

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Ascan Warnholtz

1

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5 August 2017

Nikolaus Tsilimingas

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2

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5 August 2017

Maria Wendt

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3

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5 August 2017

Thomas Münzel

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4

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5 August 2017

publication date

1 October 2002

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5 August 2017

published in

Heart Failure Reviews

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5 August 2017

volume

7

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5 August 2017

issue

4

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5 August 2017

page(s)

335-345

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Evidence for enhanced vascular superoxide anion production in nitrate tolerance. A novel mechanism underlying tolerance and cross-tolerance

5 August 2017

cites work

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Urinary NItrotyrosine Content as a Marker of Peroxynitrite-induced Tolerance to Organic NItrates

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Hydralazine prevents nitroglycerin tolerance by inhibiting activation of a membrane-bound NADH oxidase. A new action for an old drug

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Incidence of early tolerance to hemodynamic effects of continuous infusion of nitroglycerin in patients with coronary artery disease and heart failure.

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Oxidative stress increases synthesis of big endothelin-1 by activation of the endothelin-1 promoter

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Endothelial dysfunction, oxidative stress, and risk of cardiovascular events in patients with coronary artery disease

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GISSI-3: effects of lisinopril and transdermal glyceryl trinitrate singly and together on 6-week mortality and ventricular function after acute myocardial infarction. Gruppo Italiano per lo Studio della Sopravvivenza nell'infarto Miocardico

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Effects of intermittent transdermal nitroglycerin on occurrence of ischemia after patch removal: results of the second transdermal intermittent dosing evaluation study (TIDES-II).

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Superoxide generation from endothelial nitric-oxide synthase. A Ca2+/calmodulin-dependent and tetrahydrobiopterin regulatory process

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Dietary supplement with vitamin C prevents nitrate tolerance

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Double-blind, placebo-controlled study to evaluate the effect of organic nitrates in patients with chronic heart failure treated with angiotensin-converting enzyme inhibition

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Endothelial regulation of vasomotion in apoE-deficient mice: implications for interactions between peroxynitrite and tetrahydrobiopterin

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Vascular peroxynitrite formation during organic nitrate tolerance.

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Prevention of vascular nitroglycerin tolerance by inhibition of protein kinase C.

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12 December 2020

Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage

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Vasodilator-stimulated phosphoprotein serine 239 phosphorylation as a sensitive monitor of defective nitric oxide/cGMP signaling and endothelial dysfunction

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12 December 2020

Effect of in vivo nitroglycerin therapy on endothelium-dependent and independent vascular relaxation and cyclic GMP accumulation in rat aorta

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Characterization of Recombinant Human Endothelial Nitric-oxide Synthase Purified from the YeastPichia pastoris

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Nitroglycerin withdrawal increases endothelium-dependent vasomotor response to acetylcholine.

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Evidence supporting abnormalities in nitric oxide synthase function induced by nitroglycerin in humans

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Long-term nitroglycerin treatment is associated with supersensitivity to vasoconstrictors in men with stable coronary artery disease: prevention by concomitant treatment with captopril.

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12 December 2020

Effects of long-term nitroglycerin treatment on endothelial nitric oxide synthase (NOS III) gene expression, NOS III-mediated superoxide production, and vascular NO bioavailability

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12 December 2020

Prevention of tolerance to hemodynamic effects of nitrates with concomitant use of hydralazine in patients with chronic heart failure

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Oxidative stress increases endothelin-1 synthesis in human coronary artery smooth muscle cells

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12 December 2020

Lack of critical involvement of endothelial nitric oxide synthase in vascular nitrate tolerance in mice.

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12 December 2020

Long-term nitrate use may be deleterious in ischemic heart disease: A study using the databases from two large-scale postinfarction studies. Multicenter Myocardial Ischemia Research Group

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ISIS-4: a randomised factorial trial assessing early oral captopril, oral mononitrate, and intravenous magnesium sulphate in 58,050 patients with suspected acute myocardial infarction. ISIS-4 (Fourth International Study of Infarct Survival) Collabor

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Effects of in vivo nitroglycerin treatment on activity and expression of the guanylyl cyclase and cGMP-dependent protein kinase and their downstream target vasodilator-stimulated phosphoprotein in aorta.

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Prognostic impact of coronary vasodilator dysfunction on adverse long-term outcome of coronary heart disease

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Phosphorylation of Thr(495) regulates Ca(2+)/calmodulin-dependent endothelial nitric oxide synthase activity.

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Folic Acid Reverts Dysfunction of Endothelial Nitric Oxide Synthase

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Dissociation of coronary vascular tolerance and neurohormonal adjustments during long-term nitroglycerin therapy in patients with stable coronary artery disease

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Invited review: cGMP-dependent protein kinase signaling mechanisms in smooth muscle: from the regulation of tone to gene expression.

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Analysis and regulation of vasodilator-stimulated phosphoprotein serine 239 phosphorylation in vitro and in intact cells using a phosphospecific monoclonal antibody.

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Endothelial nitric oxide synthase is a site of superoxide synthesis in endothelial cells treated with glyceryl trinitrate

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Role of L-arginine in the vascular actions and development of tolerance to nitroglycerin

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12 December 2020

Desensitization of guanylate cyclase in nitrate tolerance does not impair endothelium-dependent responses

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12 December 2020

Folic acid prevents nitroglycerin-induced nitric oxide synthase dysfunction and nitrate tolerance: a human in vivo study

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12 December 2020

Nitroglycerin tolerance in human vessels: evidence for impaired nitroglycerin bioconversion

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Increased adhesion and aggregation of platelets lacking cyclic guanosine 3',5'-monophosphate kinase I.

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12 December 2020

Randomized, double-blind, placebo-controlled study of the preventive effect of supplemental oral vitamin C on attenuation of development of nitrate tolerance

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12 December 2020

Evidence for a role of endothelin 1 and protein kinase C in nitroglycerin tolerance

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12 December 2020

Therapy with nitroglycerin increases coronary vasoconstriction in response to acetylcholine

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12 December 2020

Persistent hemodynamic improvement with short-term nitrate therapy in patients with chronic congestive heart failure already treated with captopril

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12 December 2020

Defective smooth muscle regulation in cGMP kinase I-deficient mice

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12 December 2020

Expression of cGMP-dependent protein kinase I and phosphorylation of its substrate, vasodilator-stimulated phosphoprotein, in human endothelial cells of different origin

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12 December 2020

Randomized, double-blind, placebo-controlled study of supplemental vitamin E on attenuation of the development of nitrate tolerance

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12 December 2020

Effects of a nitrate-free interval on tolerance, vasoconstrictor sensitivity and vascular superoxide production

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12 December 2020

Tetrahydrobiopterin improves endothelium-dependent vasodilation in nitroglycerin-tolerant rats

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12 December 2020

Nitrate tolerance impairs nitric oxide-mediated vasodilation in vivo

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12 December 2020

Identifiers

DOI

10.1023/A:1020710417337

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Dimensions Publication ID

5 August 2017

1020727950

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