C-C chemokine receptor 6-regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE. (Q34967101)

5 August 2017

C-C chemokine receptor 6-regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE. (English)

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5 August 2017

10

Federica Sallusto

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Antonio Lanzavecchia

8

object named as

Antonio Lanzavecchia

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5 August 2017

Dirk Baumjohann

3

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Antonio Uccelli

object named as

Antonio Uccelli

7

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Britta Engelhardt

object named as

Britta Engelhardt

9

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author name string

Andrea Reboldi

1

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5 August 2017

Caroline Coisne

2

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5 August 2017

Federica Benvenuto

4

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5 August 2017

Denise Bottinelli

5

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5 August 2017

Sergio Lira

6

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5 August 2017

language of work or name

English

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publication date

22 March 2009

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5 August 2017

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5 August 2017

10

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5 August 2017

5

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5 August 2017

514-523

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IL-17 plays an important role in the development of experimental autoimmune encephalomyelitis

5 August 2017

1 reference

12 December 2020

Differential regulation of central nervous system autoimmunity by T(H)1 and T(H)17 cells.

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12 December 2020

CCR6, a CC chemokine receptor that interacts with macrophage inflammatory protein 3alpha and is highly expressed in human dendritic cells

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12 December 2020

Environmental cues, dendritic cells and the programming of tissue-selective lymphocyte trafficking

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12 December 2020

Leukocyte recruitment during onset of experimental allergic encephalomyelitis is CCR1 dependent

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12 December 2020

Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells

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12 December 2020

CCR6 expression defines regulatory effector/memory-like cells within the CD25(+)CD4+ T-cell subset.

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12 December 2020

Experimental autoimmune encephalomyelitis (EAE) in CCR2(-/-) mice: susceptibility in multiple strains

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12 December 2020

Human TH17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation

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12 December 2020

Involvement of the choroid plexus in central nervous system inflammation

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12 December 2020

CXCR3 Signaling Reduces the Severity of Experimental Autoimmune Encephalomyelitis by Controlling the Parenchymal Distribution of Effector and Regulatory T Cells in the Central Nervous System

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12 December 2020

Temporal expression and cellular origin of CC chemokine receptors CCR1, CCR2 and CCR5 in the central nervous system: insight into mechanisms of MOG-induced EAE.

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12 December 2020

Loss of T-bet, but not STAT1, prevents the development of experimental autoimmune encephalomyelitis

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12 December 2020

T-lymphocyte entry into the central nervous system

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12 December 2020

Alpha4-integrin-VCAM-1 binding mediates G protein-independent capture of encephalitogenic T cell blasts to CNS white matter microvessels

1 reference

12 December 2020

The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

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12 December 2020

Severe disease, unaltered leukocyte migration, and reduced IFN-gamma production in CXCR3-/- mice with experimental autoimmune encephalomyelitis.

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12 December 2020

CCR6 mediates dendritic cell localization, lymphocyte homeostasis, and immune responses in mucosal tissue.

1 reference

12 December 2020

Mechanisms of the adaptive immune response inside the central nervous system during inflammatory and autoimmune diseases.

1 reference

12 December 2020

The many roles of chemokines and chemokine receptors in inflammation

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12 December 2020

Migratory Activity and Functional Changes of Green Fluorescent Effector Cells before and during Experimental Autoimmune Encephalomyelitis

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12 December 2020

ICAM-1, VCAM-1, and MAdCAM-1 are expressed on choroid plexus epithelium but not endothelium and mediate binding of lymphocytes in vitro

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12 December 2020

Phenotypic and functional analysis of T cells homing into the CSF of subjects with inflammatory diseases of the CNS.

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12 December 2020

IL-12- and IL-23-modulated T cells induce distinct types of EAE based on histology, CNS chemokine profile, and response to cytokine inhibition.

1 reference

12 December 2020

IL-22 is expressed by Th17 cells in an IL-23-dependent fashion, but not required for the development of autoimmune encephalomyelitis

1 reference

12 December 2020

The ins and outs of T-lymphocyte trafficking to the CNS: anatomical sites and molecular mechanisms

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12 December 2020

Differential adhesion molecule requirements for immune surveillance and inflammatory recruitment

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12 December 2020

Basic principles of immunological surveillance of the normal central nervous system

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12 December 2020

A rush to judgment on Th17

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12 December 2020

Prevention of experimental autoimmune encephalomyelitis by antibodies against alpha 4 beta 1 integrin.

1 reference

12 December 2020

Th17 cell differentiation: the long and winding road

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12 December 2020

An overview of IL-17 function and signaling

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12 December 2020

Cutting edge: Th1 cells facilitate the entry of Th17 cells to the central nervous system during experimental autoimmune encephalomyelitis

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12 December 2020

Three or more routes for leukocyte migration into the central nervous system

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12 December 2020

TH17 cells in development: an updated view of their molecular identity and genetic programming

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12 December 2020

Astrocytes are the major intracerebral source of macrophage inflammatory protein-3alpha/CCL20 in relapsing experimental autoimmune encephalomyelitis and in vitro.

1 reference

12 December 2020

CCR5(+) and CXCR3(+) T cells are increased in multiple sclerosis and their ligands MIP-1alpha and IP-10 are expressed in demyelinating brain lesions

1 reference

12 December 2020

IL-17A and IL-17F do not contribute vitally to autoimmune neuro-inflammation in mice

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12 December 2020

IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

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12 December 2020

Regional CNS responses to IFN-gamma determine lesion localization patterns during EAE pathogenesis

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12 December 2020

Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model.

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12 December 2020

CCR6 regulates the migration of inflammatory and regulatory T cells

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12 December 2020

Molecular mechanisms involved in lymphocyte recruitment in inflamed brain microvessels: critical roles for P-selectin glycoprotein ligand-1 and heterotrimeric G(i)-linked receptors

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12 December 2020

E- and P-selectin are not involved in the recruitment of inflammatory cells across the blood-brain barrier in experimental autoimmune encephalomyelitis.

1 reference

12 December 2020

Lymphoid chemokines CCL19 and CCL21 are expressed in the central nervous system during experimental autoimmune encephalomyelitis: implications for the maintenance of chronic neuroinflammation.

1 reference

12 December 2020

B cells and multiple sclerosis

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12 December 2020

Identification through bioinformatics of two new macrophage proinflammatory human chemokines: MIP-3alpha and MIP-3beta

1 reference

12 December 2020

A few autoreactive cells in an autoimmune infiltrate control a vast population of nonspecific cells: a tale of smart bombs and the infantry

1 reference

12 December 2020

Orchestrating the orchestrators: chemokines in control of T cell traffic

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12 December 2020

Induction and effector functions of T(H)17 cells.

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12 December 2020

Interleukin-17 production in central nervous system-infiltrating T cells and glial cells is associated with active disease in multiple sclerosis

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12 December 2020

Treatment of experimental autoimmune encephalomyelitis with the chemokine receptor antagonist Met-RANTES.

1 reference

12 December 2020

Either a Th17 or a Th1 effector response can drive autoimmunity: conditions of disease induction affect dominant effector category

1 reference

12 December 2020

A brief history of T(H)17, the first major revision in the T(H)1/T(H)2 hypothesis of T cell-mediated tissue damage

1 reference

12 December 2020

Time course and distribution of inflammatory and neurodegenerative events suggest structural bases for the pathogenesis of experimental autoimmune encephalomyelitis.

1 reference

12 December 2020

IL-17 family cytokines and the expanding diversity of effector T cell lineages

1 reference

12 December 2020

Localizing central nervous system immune surveillance: meningeal antigen-presenting cells activate T cells during experimental autoimmune encephalomyelitis

1 reference

12 December 2020

IL-23 and IL-17 in the establishment of protective pulmonary CD4+ T cell responses after vaccination and during Mycobacterium tuberculosis challenge

1 reference

12 December 2020

Therapeutic efficacy of IL-17 neutralization in murine experimental autoimmune encephalomyelitis

1 reference

12 December 2020

A role for macrophage inflammatory protein-3 alpha/CC chemokine ligand 20 in immune priming during T cell-mediated inflammation of the central nervous system.

1 reference

12 December 2020

Identifiers

DOI

10.1038/NI.1716

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5 August 2017

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