CE can identify small molecules that selectively target soluble oligomers of amyloid beta protein and display antifibrillogenic activity (Q34967232)

5 August 2017

CE can identify small molecules that selectively target soluble oligomers of amyloid beta protein and display antifibrillogenic activity (English)

1 reference

5 August 2017

2

Angelo Carotti

1 reference

5 August 2017

3

Marco Catto

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5 August 2017

Raffaella Colombo

1

1 reference

5 August 2017

Marco Racchi

4

1 reference

5 August 2017

Cristina Lanni

5

1 reference

5 August 2017

Laura Verga

6

1 reference

5 August 2017

Gabriele Caccialanza

7

1 reference

5 August 2017

Ersilia De Lorenzi

8

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5 August 2017

1 April 2009

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5 August 2017

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5 August 2017

30

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5 August 2017

8

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5 August 2017

1418-1429

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Crystal structures of four morpholino-doxorubicin anticancer drugs complexed with d(CGTACG) and d(CGATCG): implications in drug-DNA crosslink

5 August 2017

1 reference

https://api.crossref.org/works/10.1002%2FELPS.200800377

Molecular mechanisms of amyloidosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FELPS.200800377

7 January 2021

Mechanisms of neuronal degeneration in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1002%2FELPS.200800377

7 January 2021

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

1 reference

https://api.crossref.org/works/10.1002%2FELPS.200800377

7 January 2021

Amyloid beta-protein fibrillogenesis. Detection of a protofibrillar intermediate.

1 reference

https://api.crossref.org/works/10.1002%2FELPS.200800377

7 January 2021

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

1 reference

https://api.crossref.org/works/10.1002%2FELPS.200800377

7 January 2021

Targeting small Abeta oligomers: the solution to an Alzheimer's disease conundrum?

1 reference

https://api.crossref.org/works/10.1002%2FELPS.200800377

7 January 2021

Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red.

1 reference

https://api.crossref.org/works/10.1002%2FELPS.200800377

7 January 2021

A beta oligomers - a decade of discovery

1 reference

https://api.crossref.org/works/10.1002%2FELPS.200800377

7 January 2021

Paradigm shifts in Alzheimer's disease and other neurodegenerative disorders: the emerging role of oligomeric assemblies

1 reference

https://api.crossref.org/works/10.1002%2FELPS.200800377

7 January 2021

Small assemblies of unmodified amyloid beta-protein are the proximate neurotoxin in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1002%2FELPS.200800377

7 January 2021

Amyloid beta-protein fibrillogenesis. Structure and biological activity of protofibrillar intermediates

1 reference

https://api.crossref.org/works/10.1002%2FELPS.200800377

7 January 2021

Different conformations of amyloid beta induce neurotoxicity by distinct mechanisms in human cortical neurons.

1 reference

https://api.crossref.org/works/10.1002%2FELPS.200800377

7 January 2021

Synaptic targeting by Alzheimer's-related amyloid beta oligomers.

1 reference

https://api.crossref.org/works/10.1002%2FELPS.200800377

7 January 2021

Protofibrillar intermediates of amyloid beta-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons.

1 reference

https://api.crossref.org/works/10.1002%2FELPS.200800377

7 January 2021

Nanoparticle-based detection in cerebral spinal fluid of a soluble pathogenic biomarker for Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1002%2FELPS.200800377

7 January 2021

Molecular dynamics simulations of spontaneous fibril formation by random-coil peptides

1 reference

https://api.crossref.org/works/10.1002%2FELPS.200800377

7 January 2021

A Oligomer-Induced Aberrations in Synapse Composition, Shape, and Density Provide a Molecular Basis for Loss of Connectivity in Alzheimer's Disease

1 reference

https://api.crossref.org/works/10.1002%2FELPS.200800377

7 January 2021

Water-soluble Abeta (N-40, N-42) oligomers in normal and Alzheimer disease brains.

1 reference

https://api.crossref.org/works/10.1002%2FELPS.200800377

7 January 2021

Abeta toxicity in Alzheimer's disease: globular oligomers (ADDLs) as new vaccine and drug targets

1 reference

https://api.crossref.org/works/10.1002%2FELPS.200800377

7 January 2021

Alzheimer's disease-affected brain: presence of oligomeric A beta ligands (ADDLs) suggests a molecular basis for reversible memory loss

1 reference

https://api.crossref.org/works/10.1002%2FELPS.200800377

7 January 2021

A specific amyloid-beta protein assembly in the brain impairs memory

1 reference

https://api.crossref.org/works/10.1002%2FELPS.200800377

7 January 2021

On the nucleation and growth of amyloid beta-protein fibrils: detection of nuclei and quantitation of rate constants

1 reference

https://api.crossref.org/works/10.1002%2FELPS.200800377

7 January 2021

Small molecule inhibitors of aggregation indicate that amyloid beta oligomerization and fibrillization pathways are independent and distinct

1 reference

https://api.crossref.org/works/10.1002%2FELPS.200800377

7 January 2021

Amyloid beta-protein oligomerization: prenucleation interactions revealed by photo-induced cross-linking of unmodified proteins

1 reference

https://api.crossref.org/works/10.1002%2FELPS.200800377

7 January 2021

Amyloid beta -protein (Abeta) assembly: Abeta 40 and Abeta 42 oligomerize through distinct pathways

1 reference

https://api.crossref.org/works/10.1002%2FELPS.200800377

7 January 2021

Amyloid beta-protein: monomer structure and early aggregation states of Abeta42 and its Pro19 alloform.

1 reference

https://api.crossref.org/works/10.1002%2FELPS.200800377

7 January 2021

Elucidating amyloid beta-protein folding and assembly: A multidisciplinary approach

1 reference

https://api.crossref.org/works/10.1002%2FELPS.200800377

7 January 2021

Capillary electrophoresis studies on the aggregation process of beta-amyloid 1-42 and 1-40 peptides

1 reference

https://api.crossref.org/works/10.1002%2FELPS.200800377

7 January 2021

Comparison of free solution capillary electrophoresis and size exclusion chromatography for quantitating non-covalent aggregation of an acylated peptide

1 reference

https://api.crossref.org/works/10.1002%2FELPS.200800377

7 January 2021

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

1 reference

https://api.crossref.org/works/10.1002%2FELPS.200800377

7 January 2021

Certain inhibitors of synthetic amyloid beta-peptide (Abeta) fibrillogenesis block oligomerization of natural Abeta and thereby rescue long-term potentiation.

1 reference

https://api.crossref.org/works/10.1002%2FELPS.200800377

7 January 2021

Targeting the neurotoxic species in Alzheimer's disease: inhibitors of Abeta oligomerization

1 reference

https://api.crossref.org/works/10.1002%2FELPS.200800377

7 January 2021

Phenol red interacts with the protofibril-like oligomers of an amyloidogenic hexapeptide NFGAIL through both hydrophobic and aromatic contacts.

1 reference

https://api.crossref.org/works/10.1002%2FELPS.200800377

7 January 2021

Insight into the kinetic of amyloid beta (1-42) peptide self-aggregation: elucidation of inhibitors' mechanism of action

1 reference

https://api.crossref.org/works/10.1002%2FELPS.200800377

7 January 2021

Sonication of proteins causes formation of aggregates that resemble amyloid

1 reference

https://api.crossref.org/works/10.1002%2FELPS.200800377

7 January 2021

Sodium dodecyl sulfate solution is an effective between-run rinse for capillary electrophoresis of samples in biological matrices

1 reference

https://api.crossref.org/works/10.1002%2FELPS.200800377

7 January 2021

Thioflavine T interaction with synthetic Alzheimer's disease beta-amyloid peptides: detection of amyloid aggregation in solution

1 reference

https://api.crossref.org/works/10.1002%2FELPS.200800377

7 January 2021

New polyphenols active on beta-amyloid aggregation

1 reference

https://api.crossref.org/works/10.1002%2FELPS.200800377

7 January 2021

Controlling {beta}-amyloid oligomerization by the use of naphthalene sulfonates: trapping low molecular weight oligomeric species

1 reference

https://api.crossref.org/works/10.1002%2FELPS.200800377

7 January 2021

Targeting soluble Abeta peptide with Tramiprosate for the treatment of brain amyloidosis.

1 reference

https://api.crossref.org/works/10.1002%2FELPS.200800377

7 January 2021

Sulfonated molecules that bind a partially structured species of beta2-microglobulin also influence refolding and fibrillogenesis

1 reference

https://api.crossref.org/works/10.1002%2FELPS.200800377

7 January 2021

Evaluation of mitoxantrone for the treatment of multiple sclerosis

1 reference

https://api.crossref.org/works/10.1002%2FELPS.200800377

7 January 2021

Interaction of the anthracycline 4'-iodo-4'-deoxydoxorubicin with amyloid fibrils: inhibition of amyloidogenesis

1 reference

https://api.crossref.org/works/10.1002%2FELPS.200800377

7 January 2021

Insights into structure-activity relationships from lipophilicity profiles of pyridin-2(1H)-one analogs of the cardiotonic agent milrinone

1 reference

https://api.crossref.org/works/10.1002%2FELPS.200800377

7 January 2021

Analytical method for beta-amyloid fibrils using CE-laser induced fluorescence and its application to screening for inhibitors of beta-amyloid protein aggregation

1 reference

https://api.crossref.org/works/10.1002%2FELPS.200800377

7 January 2021

Rifampicin does not prevent amyloid fibril formation by human islet amyloid polypeptide but does inhibit fibril thioflavin-T interactions: implications for mechanistic studies of beta-cell death

1 reference

https://api.crossref.org/works/10.1002%2FELPS.200800377

7 January 2021

Sulfonated dyes attenuate the toxic effects of beta-amyloid in a structure-specific fashion

1 reference

https://api.crossref.org/works/10.1002%2FELPS.200800377

7 January 2021

Identifiers

DOI

10.1002/ELPS.200800377

1 reference

5 August 2017

1 reference