Overexpression of the toll-like receptor (TLR) signaling adaptor MYD88, but lack of genetic mutation, in myelodysplastic syndromes (Q34970662)

5 August 2017

title

Overexpression of the toll-like receptor (TLR) signaling adaptor MYD88, but lack of genetic mutation, in myelodysplastic syndromes (English)

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5 August 2017

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10

Sherry Pierce

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5 August 2017

Guillermo Garcia-Manero

14

object named as

Guillermo Garcia-Manero

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5 August 2017

Sophie Dimicoli

1

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5 August 2017

Yue Wei

2

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5 August 2017

Carlos Bueso-Ramos

3

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5 August 2017

Hui Yang

4

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5 August 2017

Courtney Dinardo

5

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5 August 2017

Yu Jia

6

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5 August 2017

Hong Zheng

7

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5 August 2017

Zhihong Fang

8

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5 August 2017

Martin Nguyen

9

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5 August 2017

Rui Chen

11

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5 August 2017

Hui Wang

12

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5 August 2017

Chenghua Wu

13

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5 August 2017

language of work or name

English

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publication date

15 August 2013

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5 August 2017

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5 August 2017

volume

8

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5 August 2017

issue

8

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5 August 2017

page(s)

e71120

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Creative Commons Attribution 4.0 International

5 August 2017

copyright license

start time

15 August 2013

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Toll-like receptor alterations in myelodysplastic syndrome

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Global H3K4me3 genome mapping reveals alterations of innate immunity signaling and overexpression of JMJD3 in human myelodysplastic syndrome CD34+ cells.

8 July 2018

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MYD88 L265P somatic mutation in Waldenström's macroglobulinemia.

8 July 2018

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Validation of a prognostic model and the impact of mutations in patients with lower-risk myelodysplastic syndromes

8 July 2018

1 reference

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Cytotoxic effects of bortezomib in myelodysplastic syndrome/acute myeloid leukemia depend on autophagy-mediated lysosomal degradation of TRAF6 and repression of PSMA1.

8 July 2018

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Coordinate loss of a microRNA and protein-coding gene cooperate in the pathogenesis of 5q- syndrome

8 July 2018

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Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia

8 July 2018

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Chronic exposure to a TLR ligand injures hematopoietic stem cells

8 July 2018

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Oncogenically active MYD88 mutations in human lymphoma

8 July 2018

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Innate immune signaling in the myelodysplastic syndromes

8 July 2018

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Erythroid progenitor cells expanded from peripheral blood without mobilization or preselection: molecular characteristics and functional competence

8 July 2018

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PKC-alpha controls MYD88-dependent TLR/IL-1R signaling and cytokine production in mouse and human dendritic cells.

8 July 2018

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The role of p38 mitogen-activated protein kinase in serum-induced leukemia inhibitory factor secretion by bone marrow stromal cells from pediatric myelodysplastic syndromes

8 July 2018

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Identification of miR-145 and miR-146a as mediators of the 5q- syndrome phenotype

8 July 2018

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TLR4 signaling induced by lipopolysaccharide or paclitaxel regulates tumor survival and chemoresistance in ovarian cancer.

8 July 2018

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ATM mediates constitutive NF-kappaB activation in high-risk myelodysplastic syndrome and acute myeloid leukemia

8 July 2018

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Demonstration of inflammation-induced cancer and cancer immunoediting during primary tumorigenesis

8 July 2018

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The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycomb-mediated gene silencing

8 July 2018

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Toll-like receptors on hematopoietic progenitor cells stimulate innate immune system replenishment

8 July 2018

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Pathogen recognition and innate immunity

8 July 2018

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8 July 2018

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Localization of TLR2 and MyD88 to Chlamydia trachomatis inclusions. Evidence for signaling by intracellular TLR2 during infection with an obligate intracellular pathogen.

8 July 2018

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Loss of gata1 but not gata2 converts erythropoiesis to myelopoiesis in zebrafish embryos

8 July 2018

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GATA-1-dependent transcriptional repression of GATA-2 via disruption of positive autoregulation and domain-wide chromatin remodeling

8 July 2018

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A universal role for MyD88 in TLR/IL-1R-mediated signaling

8 July 2018

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Micrococci and peptidoglycan activate TLR2-->MyD88-->IRAK-->TRAF-->NIK-->IKK-->NF-kappaB signal transduction pathway that induces transcription of interleukin-8

8 July 2018

1 reference

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Erythroid progenitors differentiate and mature in response to endogenous erythropoietin

8 July 2018

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Transcription factor GATA-1 permits survival and maturation of erythroid precursors by preventing apoptosis

8 July 2018

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Acute Myelogenous Leukemia: A Human Cell Line Responsive to Colony-Stimulating Activity

8 July 2018

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Myelodysplastic Syndromes

8 July 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0071120

Differential involvement of BB loops of toll-IL-1 resistance (TIR) domain-containing adapter proteins in TLR4- versus TLR2-mediated signal transduction.

21 January 2018

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Effect of all-trans retinoic acid on chemotherapy induced apoptosis and down-regulation of Bcl-2 in human myeloid leukaemia CD34 positive cells.

21 January 2018

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STAT3-driven upregulation of TLR2 promotes gastric tumorigenesis independent of tumor inflammation.

21 January 2018

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Peptide-mediated interference of TIR domain dimerization in MyD88 inhibits interleukin-1-dependent activation of NF-{kappa}B

21 January 2018

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12 December 2020

Toll-like receptor-4 is up-regulated in hematopoietic progenitor cells and contributes to increased apoptosis in myelodysplastic syndromes

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12 December 2020

Absence of MYD88 gene mutation in acute leukemias and multiple myelomas

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12 December 2020

Lipopolysaccharide stimulates the MyD88-independent pathway and results in activation of IFN-regulatory factor 3 and the expression of a subset of lipopolysaccharide-inducible genes

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12 December 2020

10.1371/JOURNAL.PONE.0071120

Identifiers

DOI

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5 August 2017

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5 August 2017

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