Blockade of the serotonin 5-HT2A receptor suppresses cue-evoked reinstatement of cocaine-seeking behavior in a rat self-administration model (Q34971199)

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English	Blockade of the serotonin 5-HT2A receptor suppresses cue-evoked reinstatement of cocaine-seeking behavior in a rat self-administration model	scientific article

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scholarly article

1 reference

Europe PubMed Central

5 August 2017

Blockade of the serotonin 5-HT2A receptor suppresses cue-evoked reinstatement of cocaine-seeking behavior in a rat self-administration model (English)

1 reference

Europe PubMed Central

5 August 2017

0 references

author name string

B A Nic Dhonnchadha

1

1 reference

Europe PubMed Central

5 August 2017

R G Fox

2

1 reference

Europe PubMed Central

5 August 2017

S J Stutz

3

1 reference

Europe PubMed Central

5 August 2017

K C Rice

4

1 reference

Europe PubMed Central

5 August 2017

K A Cunningham

5

1 reference

Europe PubMed Central

5 August 2017

language of work or name

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based on heuristic

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publication date

1 April 2009

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Europe PubMed Central

5 August 2017

Behavioral Neuroscience

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Europe PubMed Central

5 August 2017

123

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Europe PubMed Central

5 August 2017

2

1 reference

Europe PubMed Central

5 August 2017

382-396

1 reference

Europe PubMed Central

5 August 2017

A comparison of the effects of different operant training experiences and dietary restriction on the reinstatement of cocaine-seeking in rats

1 reference

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8 July 2018

The 5-HT2C receptor agonist Ro60-0175 reduces cocaine self-administration and reinstatement induced by the stressor yohimbine, and contextual cues

1 reference

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8 July 2018

Experience-dependent effects of cocaine self-administration/conditioning on prefrontal and accumbens dopamine responses

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8 July 2018

Effects of cocaine and MDMA self-administration on serotonin transporter availability in monkeys

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8 July 2018

Serotonergic drugs : effects on appetite expression and use for the treatment of obesity

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8 July 2018

Chronic food restriction: enhancing effects on drug reward and striatal cell signaling

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8 July 2018

5-Hydroxytryptamine (serotonin)2A receptors in rat anterior cingulate cortex mediate the discriminative stimulus properties of d-lysergic acid diethylamide

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8 July 2018

Cocaine-mediated supersensitivity of 5-HT2A receptors in hypothalamic paraventricular nucleus is a withdrawal-induced phenomenon.

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8 July 2018

Serotonin 5-HT2A and 5-HT2C receptors as potential targets for modulation of psychostimulant use and dependence

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8 July 2018

Measuring craving: an attempt to connect subjective craving with cue reactivity

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8 July 2018

Determining the region-specific contributions of 5-HT receptors to the psychostimulant effects of cocaine.

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Relationship of cocaine-induced c-Fos expression to behaviors and the role of serotonin 5-HT2A receptors in cocaine-induced c-Fos expression.

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The activation of 5-HT receptors in prefrontal cortex enhances dopaminergic activity

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Evidence for the preferential involvement of 5-HT2A serotonin receptors in stress- and drug-induced dopamine release in the rat medial prefrontal cortex

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The selective 5-HT2A receptor antagonist M100907 enhances antidepressant-like behavioral effects of the SSRI fluoxetine

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8 July 2018

Role of serotonin (5-HT)2 receptors in cocaine self-administration and seeking behavior in rats

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8 July 2018

Inactivation of 5-HT(2C) receptors potentiates consequences of serotonin reuptake blockade

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8 July 2018

Serotonin receptor ligands and the treatment of obesity

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Contribution of serotonin (5-hydroxytryptamine; 5-HT) 5-HT2 receptor subtypes to the hyperlocomotor effects of cocaine: acute and chronic pharmacological analyses

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5-HT2 receptors.

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8 July 2018

Phasic alterations in dopamine and serotonin release in striatum and prefrontal cortex in response to cocaine predictive cues in behaving rhesus macaques

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8 July 2018

Long-lasting effects of chronic stress on DOI-induced hyperthermia in male rats

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8 July 2018

The reinstatement model of drug relapse: history, methodology and major findings

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8 July 2018

Differential effects of the 5-HT(2A) receptor antagonist M100907 and the 5-HT(2C) receptor antagonist SB242084 on cocaine-induced locomotor activity, cocaine self-administration and cocaine-induced reinstatement of responding

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Psychomotor stimulant addiction: a neural systems perspective.

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M-100907 (Aventis).

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8 July 2018

Cocaine self-administration behavior can be reduced or potentiated by the addition of specific dopamine concentrations in the nucleus accumbens and amygdala using in vivo microdialysis

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8 July 2018

Ventral pallidal extracellular fluid levels of dopamine, serotonin, gamma amino butyric acid, and glutamate during cocaine self-administration in rats.

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8 July 2018

Using cue reactivity to evaluate medications for treatment of cocaine dependence: a critical review

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8 July 2018

Factors that determine a propensity for cocaine-seeking behavior during abstinence in rats

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8 July 2018

Control of cocaine-seeking behavior by drug-associated stimuli in rats: effects on recovery of extinguished operant-responding and extracellular dopamine levels in amygdala and nucleus accumbens

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8 July 2018

Meta-analysis of cue-reactivity in addiction research

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8 July 2018

Serotonin and stress

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8 July 2018

Selectivity of action of typical and atypical anti-psychotic drugs as antagonists of the behavioral effects of 1-[2,5-dimethoxy-4-iodophenyl]-2-aminopropane (DOI).

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8 July 2018

Discriminative stimulus properties of the novel serotonin (5-HT)2C receptor agonist, RO 60-0175: a pharmacological analysis.

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8 July 2018

Progressive-ratio schedules of drug delivery in the analysis of drug self-administration: a review

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8 July 2018

Hostility is associated with a heightened prolactin response to meta-chlorophenylpiperazine in abstinent cocaine addicts.

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8 July 2018

Time-dependent changes in cocaine-seeking behavior and extracellular dopamine levels in the amygdala during cocaine withdrawal.

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8 July 2018

Conditioning factors in drug abuse: can they explain compulsion?

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8 July 2018

Individual differences in cue reactivity among smokers trying to quit: effects of gender and cue type.

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Disruption of latent inhibition in the rat by the 5-HT2 agonist DOI: effects of MDL 100,907, clozapine, risperidone and haloperidol

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8 July 2018

Lesions of the basolateral amygdala abolish the ability of drug associated cues to reinstate responding during withdrawal from self-administered cocaine

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8 July 2018

A critique of fixed and progressive ratio schedules used to examine the neural substrates of drug reinforcement

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8 July 2018

Serotonergic mechanisms involved in the discriminative stimulus, reinforcing and subjective effects of cocaine

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Dopamine overflow in the nucleus accumbens during extinction and reinstatement of cocaine self-administration behavior.

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Extracellular serotonin is decreased in the nucleus accumbens during withdrawal from cocaine self-administration

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Stress: a major variable in the psychopharmacologic response.

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Neurobiology of addiction

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8 July 2018

Pharmacologic characterization of the human 5-hydroxytryptamine2B receptor: evidence for species differences

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Preclinical characterization of the potential of the putative atypical antipsychotic MDL 100,907 as a potent 5-HT2A antagonist with a favorable CNS safety profile

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8 July 2018

5-HT2 receptor subtypes: a family re-united?

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8 July 2018

Protein kinases that phosphorylate activated G protein-coupled receptors.

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8 July 2018

Serotonin dysfunction in the nucleus accumbens of rats during withdrawal after unlimited access to intravenous cocaine

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8 July 2018

Effects of two stressors on behaviour in the elevated X-maze: preliminary investigation of their interaction with 8-OH-DPAT.

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8 July 2018

Blockade of the discriminative stimulus effects of DOI by MDL 100,907 and the 'atypical' antipsychotics, clozapine and risperidone

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8 July 2018

The role of food deprivation in the maintenance and reinstatement of cocaine-seeking behavior in rats.

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8 July 2018

Abstinence symptomatology and psychiatric diagnosis in cocaine abusers. Clinical observations.

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8 July 2018

Monoamine metabolism and its responses to food deprivation in the brain of Zucker rats

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8 July 2018

Interaction of reinforcement history with methadone on responding maintained under a fixed-interval schedule.

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8 July 2018

Dopamine in the nucleus accumbens during cocaine self-administration as studied by in vivo microdialysis

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8 July 2018

Effects of conditioned running on plasma, liver and brain tryptophan and on brain 5-hydroxytryptamine metabolism of the rat.

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8 July 2018

Continuous cocaine administration produces persisting changes in brain neurochemistry and behavior

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8 July 2018

Repeated administration of low doses of cocaine enhances the sensitivity of 5-HT2 receptor function

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8 July 2018

Chronic cocaine enhances serotonin autoregulation and serotonin uptake binding

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8 July 2018

Molecular geometry of inhibitors of the uptake of catecholamines and serotonin in synaptosomal preparations of rat brain

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8 July 2018

d-amphetamine and fixed-interval performance: effects of operant history

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8 July 2018

Food restriction enhances peak corticosterone levels, cocaine-induced locomotor activity, and DeltaFosB expression in the nucleus accumbens of the rat.

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26 October 2018

Stimulation of 5-HT2C receptors attenuates cue and cocaine-primed reinstatement of cocaine-seeking behavior in rats

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26 October 2018

Stimulation of serotonin2C receptors influences cocaine-seeking behavior in response to drug-associated stimuli in rats

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26 October 2018

Context-dependent prefrontal cortex regulation of cocaine self-administration and reinstatement behaviors in rats.

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26 October 2018

Biphasic alterations in serotonin-1B (5-HT1B) receptor function during abstinence from extended cocaine self-administration.

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26 October 2018

Serotonergic responsiveness in human cocaine users.

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26 October 2018

Relationship of disinhibition and aggression to blunted prolactin response to meta-chlorophenylpiperazine in cocaine-dependent patients

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26 October 2018

Dissociable contribution of 5-HT1A and 5-HT2A receptors in the medial prefrontal cortex to different aspects of executive control such as impulsivity and compulsive perseveration in rats

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26 October 2018

Involvement of the dorsal striatum in cue-controlled cocaine seeking.

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26 October 2018

Risperidone diminishes cocaine-induced craving

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26 October 2018

Individual differences in sensitivity to factors provoking reinstatement of cocaine-seeking behavior.

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26 October 2018

Relationship between serotonin transporter gene polymorphisms and platelet serotonin transporter sites among African-American cocaine-dependent individuals and healthy volunteers

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26 October 2018

1 reference

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26 October 2018

Injection of the 5-HT2C receptor agonist Ro60-0175 into the ventral tegmental area reduces cocaine-induced locomotor activity and cocaine self-administration

1 reference

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26 October 2018

Differential roles of 5-HT receptor subtypes in cue and cocaine reinstatement of cocaine-seeking behavior in rats

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26 October 2018

Selective inactivation of the dorsomedial prefrontal cortex and the basolateral amygdala attenuates conditioned-cued reinstatement of extinguished cocaine-seeking behavior in rats

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26 October 2018

Escalation of cocaine self-administration does not depend on altered cocaine-induced nucleus accumbens dopamine levels.

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26 October 2018

Discriminative stimulus properties of (+/-)-fenfluramine: the role of 5-HT2 receptor subtypes

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26 October 2018

Subsecond dopamine release promotes cocaine seeking.

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26 October 2018

Relationships between individual sensitivity to CS- and cocaine-induced reinstatement in the rat.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3830454

26 October 2018

SR46349-B, a 5-HT(2A/2C) receptor antagonist, potentiates haloperidol-induced dopamine release in rat medial prefrontal cortex and nucleus accumbens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3830454

26 October 2018

Dopamine release in the dorsal striatum during cocaine-seeking behavior under the control of a drug-associated cue.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3830454

26 October 2018

Blockade of stress-induced but not cocaine-induced reinstatement by infusion of noradrenergic antagonists into the bed nucleus of the stria terminalis or the central nucleus of the amygdala.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3830454

26 October 2018

3,4-Methylenedioxymethamphetamine (MDMA, "ecstasy") and its stereoisomers as reinforcers in rhesus monkeys: serotonergic involvement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3830454

26 October 2018

Dissociable effects of lidocaine inactivation of the rostral and caudal basolateral amygdala on the maintenance and reinstatement of cocaine-seeking behavior in rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3830454

26 October 2018

Pharmacological studies of the acute effects of (+)-3,4-methylenedioxymethamphetamine on locomotor activity: role of 5-HT(1B/1D) and 5-HT(2) receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3830454

26 October 2018

An in vivo binding assay to determine central alpha(1)-adrenoceptor occupancy using [(3)H]prazosin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3830454

26 October 2018

Conditioned reinstatement of drug-seeking behavior with a discrete compound stimulus classically conditioned with intravenous cocaine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3830454

26 October 2018

Modulation of 5-HT(2A) receptor-mediated head-twitch behaviour in the rat by 5-HT(2C) receptor agonists

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3830454

26 October 2018

Brain serotonin metabolism during water deprivation and hydration in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3830454

26 October 2018

Influence of individual differences and chronic fluoxetine treatment on cocaine-seeking behavior in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3830454

26 October 2018

Antagonism of 5-hydroxytryptamine(2a) receptors attenuates the behavioral effects of cocaine in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3830454

26 October 2018

Effects of the serotonin 5-HT(2) antagonist, ritanserin, and the serotonin 5-HT(1A) antagonist, WAY 100635, on cocaine-seeking in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3830454

26 October 2018

Studies to investigate the role of 5-HT(2C) receptors on cocaine- and food-maintained behavior.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3830454

26 October 2018

Leftward shift in the acquisition of cocaine self-administration in isolation-reared rats: relationship to extracellular levels of dopamine, serotonin and glutamate in the nucleus accumbens and amygdala-striatal FOS expression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3830454

26 October 2018

The relationship between anxiety levels and outcome of cocaine abuse treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3830454

26 October 2018

Acute and protracted cocaine abstinence in an outpatient population: a prospective study of mood, sleep and withdrawal symptoms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3830454

26 October 2018

Predicting relapse to cocaine-seeking behavior: a multiple regression approach.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3830454

26 October 2018

Dissociation of primary and secondary reward-relevant limbic nuclei in an animal model of relapse.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3830454

26 October 2018

Cocaine self-administration increases the incentive motivational properties of the drug in rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3830454

26 October 2018

Alterations in serotonergic responsiveness during cocaine withdrawal in rats: similarities to major depression in humans.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3830454

26 October 2018

Cocaine, ethanol, and genotype effects on human midbrain serotonin transporter binding sites and mRNA levels.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3830454

26 October 2018

Differences in extracellular dopamine concentrations in the nucleus accumbens during response-dependent and response-independent cocaine administration in the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3830454

26 October 2018

Effects of corticosterone on 5-HT1A and 5-HT2 receptor binding and on the receptor-mediated behavioral responses of rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3830454

26 October 2018

Acute pharmacological blockade of corticosterone secretion reverses food restriction-induced sensitization of the locomotor response to cocaine.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3830454

26 October 2018

Chronic cocaine exposure potentiates prolactin and head shake responses to 5-HT2 receptor stimulation in rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3830454

26 October 2018

Repeated cocaine administration does not affect 5-HT receptor subtypes (5-HT1A, 5-HT2) in several rat brain regions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3830454

26 October 2018

Parameters of self-administration of cocaine in rats under a progressive-ratio schedule.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3830454

26 October 2018

Time-dependent changes in sensitivity to apomorphine and monoamine receptors following withdrawal from continuous cocaine administration in rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3830454

26 October 2018

Effects of chlorisondamine and restraint on cortical [3H]ketanserin binding, 5-HT2A receptor-mediated head shakes, and behaviours in models of anxiety.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3830454

26 October 2018

Conditioned cocaine induced hyperactivity: an association with increased medial prefrontal cortex serotonin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3830454

26 October 2018

Influence of repeated cocaine exposure on the endocrine and behavioral responses to stress in rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3830454

26 October 2018

Acute immobilization stress reduces (+/-)DOI-induced 5-HT2A receptor-mediated head shakes in rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3830454

26 October 2018

Long-lasting effects of an acute stress on the neurochemistry and function of 5-hydroxytryptaminergic neurones in the mouse brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3830454

26 October 2018

Effects of chronic cocaine administration on the serotonergic system in the rat brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3830454

26 October 2018

Differences between responders and nonresponders to cocaine cues in the laboratory.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3830454

26 October 2018

3-H-ketanserin (serotonin type 2) binding in the rat frontal cortex: effect of immobilization stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/19331461

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of imipramine and serotonin-2 agonists and antagonists on serotonin-2 and beta-adrenergic receptors following noradrenergic or serotonergic denervation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19331461

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid desensitization and down-regulation of 5-HT2 receptors by DOM treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/19331461

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1037/A0014592

1 reference

Europe PubMed Central

5 August 2017

1 reference

Europe PubMed Central

5 August 2017

1 reference

Europe PubMed Central

5 August 2017

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