PKC activation in Niemann pick C1 cells restores subcellular cholesterol transport (Q34974271)

5 August 2017

title

PKC activation in Niemann pick C1 cells restores subcellular cholesterol transport (English)

1 reference

5 August 2017

Farshad Tamari

1

1 reference

5 August 2017

Fannie W Chen

2

1 reference

5 August 2017

Chunlei Li

3

1 reference

5 August 2017

Jagrutiben Chaudhari

4

1 reference

5 August 2017

Yiannis A Ioannou

5

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5 August 2017

language of work or name

English

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publication date

15 August 2013

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5 August 2017

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5 August 2017

volume

8

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5 August 2017

issue

8

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5 August 2017

page(s)

e74169

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Creative Commons Attribution 4.0 International

5 August 2017

copyright license

start time

15 August 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Endosomal lipid accumulation in NPC1 leads to inhibition of PKC, hypophosphorylation of vimentin and Rab9 entrapment

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Diazoxide acts more as a PKC-epsilon activator, and indirectly activates the mitochondrial K(ATP) channel conferring cardioprotection against hypoxic injury

8 July 2018

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The linoleic acid derivative DCP-LA selectively activates PKC-epsilon, possibly binding to the phosphatidylserine binding site

8 July 2018

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Specific in vivo phosphorylation sites determine the assembly dynamics of vimentin intermediate filaments

8 July 2018

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Telomerase immortalization upregulates Rab9 expression and restores LDL cholesterol egress from Niemann-Pick C1 late endosomes

8 July 2018

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Associations of PKC isoforms with the cytoskeleton of B16F10 melanoma cells

8 July 2018

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Niemann-pick type C1 (NPC1) overexpression alters cellular cholesterol homeostasis

8 July 2018

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Niemann-Pick C1 is a late endosome-resident protein that transiently associates with lysosomes and the trans-Golgi network

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Expression, subcellular distribution and response to phorbol esters of protein kinase C (PKC) isozymes in drug-sensitive and multidrug-resistant KB cells evidence for altered regulation of PKC-alpha

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8 July 2018

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Type C Niemann-Pick disease: a murine model of the lysosomal cholesterol lipidosis accumulates sphingosine and sphinganine in liver

8 July 2018

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NPC1 late endosomes contain elevated levels of non-esterified ('free') fatty acids and an abnormally glycosylated form of the NPC2 protein

8 July 2018

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Cholesterol modulates membrane traffic along the endocytic pathway in sphingolipid-storage diseases

21 January 2018

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Modulation of protein kinase C by endogenous sphingosine: inhibition of phorbol dibutyrate binding in Niemann-Pick C fibroblasts

21 January 2018

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Suppression of macrophage eicosanoid synthesis by atherogenic lipoproteins is profoundly affected by cholesterol-fatty acyl esterification and the Niemann-Pick C pathway of lipid trafficking

21 January 2018

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The newly synthesized linoleic acid derivative FR236924 induces a long-lasting facilitation of hippocampal neurotransmission by targeting nicotinic acetylcholine receptors

21 January 2018

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A genetic storage disorder in BALB/C mice with a metabolic block in esterification of exogenous cholesterol

26 October 2018

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12 December 2020

Selective regulation of protein kinase C isoenzymes by oleic acid in human platelets

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12 December 2020

Phosphorylation of vimentin is an intermediate step in protein kinase C-mediated glycoconjugate secretion

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12 December 2020

Phorbol esters and PKC signaling regulate proliferation, vimentin cytoskeleton assembly and glutamine synthetase activity of chick embryo cerebrum astrocytes in culture

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12 December 2020

The Npc1 mutation causes an altered expression of caveolin-1, annexin II and protein kinases and phosphorylation of caveolin-1 and annexin II in murine livers

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12 December 2020

Vimentin-dependent spatial translocation of an activated MAP kinase in injured nerve

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12 December 2020

10.1371/JOURNAL.PONE.0074169

Identifiers

DOI

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5 August 2017

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5 August 2017

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