GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy (Q34974751)

5 August 2017

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GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy (English)

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genome-wide association study

5 August 2017

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author

Thor Aspelund

13

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5 August 2017

27

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29

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5 August 2017

31

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5 August 2017

37

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5 August 2017

45

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5 August 2017

Cornelia M. van Duijn

46

Cornelia M van Duijn

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André Uitterlinden

32

André G Uitterlinden

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Emelia J. Benjamin

14

Emelia J Benjamin

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Joris Deelen

Joris Deelen

3

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Jessica D. Faul

Jessica D Faul

5

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Jennifer A Smith

Jennifer A Smith

8

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David Karasik

David Karasik

39

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Albert V. Smith

Albert V Smith

9

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Douglas P. Kiel

Douglas P Kiel

22

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Tom Perls

Thomas T Perls

41

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Kathryn L. Lunetta

Kathryn L Lunetta

6

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Paola Sebastiani

Paola Sebastiani

7

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Jerome I Rotter

28

Jerome I Rotter

1 reference

5 August 2017

38

Tamara B Harris

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5 August 2017

19

Albert Hofman

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5 August 2017

36

Luigi Ferrucci

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5 August 2017

35

David A Bennett

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5 August 2017

40

Lenore J Launer

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5 August 2017

30

Andrew Singleton

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5 August 2017

34

Stefania Bandinelli

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5 August 2017

26

Bruce M Psaty

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5 August 2017

21

Sharon L R Kardia

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5 August 2017

15

Philip L De Jager

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5 August 2017

42

P Eline Slagboom

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5 August 2017

10

Toshiko Tanaka

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5 August 2017

23

Ben A Oostra

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5 August 2017

47

Joanne M Murabito

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5 August 2017

44

David R Weir

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5 August 2017

43

Gregory J Tranah

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5 August 2017

1

Linda Broer

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5 August 2017

18

Melissa E Garcia

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5 August 2017

25

Neeta Parimi

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5 August 2017

4

Daniel S Evans

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5 August 2017

24

Eric S Orwoll

1 reference

5 August 2017

16

Gudny Eirkisdottir

1 reference

5 August 2017

12

Alice M Arnold

1 reference

5 August 2017

2

Aron S Buchman

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5 August 2017

17

Denis A Evans

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5 August 2017

Lei Yu

11

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5 August 2017

Robert C Kaplan

20

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5 August 2017

Wei Zhao

33

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5 August 2017

language of work or name

English

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publication date

8 September 2014

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The Journals of Gerontology

5 August 2017

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5 August 2017

70

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5 August 2017

1

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5 August 2017

110-118

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Cloud computing for detecting high-order genome-wide epistatic interaction via dynamic clustering

5 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4296168

Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4296168

Leukocyte telomere length associates with prospective mortality independent of immune-related parameters and known genetic markers

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4296168

On genome-wide association studies and their meta-analyses: lessons learned from osteoporosis studies

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4296168

Identification of seven loci affecting mean telomere length and their association with disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4296168

Genome-wide linkage analysis for human longevity: Genetics of Healthy Aging Study

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4296168

Technical reproducibility of genotyping SNP arrays used in genome-wide association studies

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4296168

Review: a meta-analysis of GWAS and age-associated diseases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4296168

Genetic investigation of FOXO3A requires special attention due to sequence homology with FOXO3B

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4296168

Epigenome-wide scans identify differentially methylated regions for age and age-related phenotypes in a healthy ageing population

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4296168

The search for longevity and healthy aging genes: insights from epidemiological studies and samples of long-lived individuals

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4296168

FOXO3 gene variants and human aging: coding variants may not be key players

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4296168

Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4296168

Genetic signatures of exceptional longevity in humans

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4296168

A genome-wide association study of aging

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4296168

Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4296168

GCTA: a tool for genome-wide complex trait analysis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4296168

Replication of an association of variation in the FOXO3A gene with human longevity using both case-control and longitudinal data

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4296168

Uncovering the roles of rare variants in common disease through whole-genome sequencing

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4296168

A meta-analysis of four genome-wide association studies of survival to age 90 years or older: the Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4296168

Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium: Design of prospective meta-analyses of genome-wide association studies from 5 cohorts

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4296168

Genetic association of FOXO1A and FOXO3A with longevity trait in Han Chinese populations.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4296168

Epigenetic factors in aging and longevity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4296168

Nonagenarian siblings and their offspring display lower risk of mortality and morbidity than sporadic nonagenarians: The Leiden Longevity Study.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4296168

Association of FOXO3A variation with human longevity confirmed in German centenarians

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4296168

FOXO3A genotype is strongly associated with human longevity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4296168

A physiologic index of comorbidity: relationship to mortality and disability

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4296168

Adapting proteostasis for disease intervention

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4296168

8 July 2018

Identifiers

DOI

10.1093/GERONA/GLU166

1 reference

5 August 2017

1 reference

5 August 2017

1 reference