The role of phosphatidic acid in the regulation of the Ras/MEK/Erk signaling cascade (Q34980709)

5 August 2017

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title

The role of phosphatidic acid in the regulation of the Ras/MEK/Erk signaling cascade (English)

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5 August 2017

Bradley T Andresen

1

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5 August 2017

Mark A Rizzo

series ordinal

2

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5 August 2017

Kuntala Shome

series ordinal

3

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5 August 2017

Guillermo Romero

series ordinal

4

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5 August 2017

language of work or name

English

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publication date

1 October 2002

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5 August 2017

4

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based on heuristic

inferred from page(s)

published in

FEBS Letters

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5 August 2017

531

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5 August 2017

1

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5 August 2017

65-68

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Phosphatidic acid-mediated mitogenic activation of mTOR signaling

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Raf-1 kinase possesses distinct binding domains for phosphatidylserine and phosphatidic acid. Phosphatidic acid regulates the translocation of Raf-1 in 12-O-tetradecanoylphorbol-13-acetate-stimulated Madin-Darby canine kidney cells

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Phosphatidic acid activation of protein kinase C-zeta overexpressed in COS cells: comparison with other protein kinase C isotypes and other acidic lipids

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A novel protein kinase target for the lipid second messenger phosphatidic acid

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Phospholipase D and its product, phosphatidic acid, mediate agonist-dependent raf-1 translocation to the plasma membrane and the activation of the mitogen-activated protein kinase pathway

21 January 2018

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The recruitment of Raf-1 to membranes is mediated by direct interaction with phosphatidic acid and is independent of association with Ras.

21 January 2018

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Phosphatidic acid regulates tyrosine phosphorylating activity in human neutrophils: enhancement of Fgr activity

21 January 2018

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Tight binding inhibition of protein phosphatase-1 by phosphatidic acid. Specificity of inhibition by the phospholipid

21 January 2018

1 reference

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Activation of human neutrophil NADPH oxidase by phosphatidic acid or diacylglycerol in a cell-free system. Activity of diacylglycerol is dependent on its conversion to phosphatidic acid

21 January 2018

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Cell-free activation of neutrophil NADPH oxidase by a phosphatidic acid-regulated protein kinase

21 January 2018

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Phosphatidic acid-mediated phosphorylation of the NADPH oxidase component p47-phox. Evidence that phosphatidic acid may activate a novel protein kinase.

21 January 2018

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Differential binding of traffic-related proteins to phosphatidic acid- or phosphatidylinositol (4,5)- bisphosphate-coupled affinity reagents

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Phospholipase D-structure, regulation and function

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Properties and functions of diacylglycerol kinases

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Regulation of phospholipase D.

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ARF proteins mediate insulin-dependent activation of phospholipase D

21 January 2018

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The Ras-Raf relationship: an unfinished puzzle

21 January 2018

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Associations of B- and C-Raf with cholesterol, phosphatidylserine, and lipid second messengers: preferential binding of Raf to artificial lipid rafts.

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Differential internalization of mammalian and non-mammalian gonadotropin-releasing hormone receptors. Uncoupling of dynamin-dependent internalization from mitogen-activated protein kinase signaling

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Agonist-dependent traffic of raft-associated Ras and Raf-1 is required for activation of the mitogen-activated protein kinase cascade

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Dynamin is membrane-active: lipid insertion is induced by phosphoinositides and phosphatidic acid

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Coupled inositide phosphorylation and phospholipase D activation initiates clathrin-coat assembly on lysosomes.

21 January 2018

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Endophilin I mediates synaptic vesicle formation by transfer of arachidonate to lysophosphatidic acid.

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Phospholipase D stimulates release of nascent secretory vesicles from the trans-Golgi network

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CtBP/BARS induces fission of Golgi membranes by acylating lysophosphatidic acid

21 January 2018

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Secretory vesicle budding from the trans-Golgi network is mediated by phosphatidic acid levels.

21 January 2018

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Lipids, lipid modification and lipid-protein interaction in membrane budding and fission--insights from the roles of endophilin A1 and synaptophysin in synaptic vesicle endocytosis

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Kinase suppressor of Ras (KSR) is a scaffold which facilitates mitogen-activated protein kinase activation in vivo

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KSR is a scaffold required for activation of the ERK/MAPK module

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Phosphatidic acid formation by phospholipase D is required for transport from the endoplasmic reticulum to the Golgi complex

21 January 2018

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Phospholipase D mediates matrix metalloproteinase-9 secretion in phorbol ester-stimulated human fibrosarcoma cells

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The cAMP-specific phosphodiesterase PDE4D3 is regulated by phosphatidic acid binding. Consequences for cAMP signaling pathway and characterization of a phosphatidic acid binding site

7 January 2021

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Binding of phosphatidic acid to the protein-tyrosine phosphatase SHP-1 as a basis for activity modulation

7 January 2021

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ADP-ribosylation factor proteins mediate agonist-induced activation of phospholipase D

7 January 2021

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Angiotensin II signaling to phospholipase D in renal microvascular smooth muscle cells in SHR

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Dynamin is required for the activation of mitogen-activated protein (MAP) kinase by MAP kinase kinase

7 January 2021

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10.1016/S0014-5793(02)03483-X

7 January 2021

Identifiers

DOI

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5 August 2017

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