Stem and progenitor cell-based therapy in ischaemic heart disease: promise, uncertainties, and challenges (Q34981433)

5 August 2017

1 reference

title

Stem and progenitor cell-based therapy in ischaemic heart disease: promise, uncertainties, and challenges (English)

1 reference

arteriosclerotic heart disease

5 August 2017

1 reference

3

Ulf Landmesser

1 reference

5 August 2017

Jörn Tongers

1

1 reference

PubMed ID

21362705

5 August 2017

Douglas W Losordo

series ordinal

2

1 reference

5 August 2017

28 February 2011

1 reference

5 August 2017

European Heart Journal

1 reference

5 August 2017

32

1 reference

5 August 2017

10

1 reference

5 August 2017

1197-1206

1 reference

Induced pluripotent stem cells: developmental biology to regenerative medicine

5 August 2017

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8 July 2018

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The acute and long-term effects of intracoronary Stem cell Transplantation in 191 patients with chronic heARt failure: the STAR-heart study

8 July 2018

1 reference

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CXCR4 blockade augments bone marrow progenitor cell recruitment to the neovasculature and reduces mortality after myocardial infarction

8 July 2018

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Regulation of bone marrow-derived vascular progenitor cell mobilization and maintenance

8 July 2018

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Cardiomyogenic potential of C-kit(+)-expressing cells derived from neonatal and adult mouse hearts

8 July 2018

1 reference

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Human cardiospheres are a source of stem cells with cardiomyogenic potential

8 July 2018

1 reference

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Enhancing the outcome of cell therapy for cardiac repair: progress from bench to bedside and back

8 July 2018

1 reference

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Pregenerative medicine: developmental paradigms in the biology of cardiovascular regeneration

8 July 2018

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Clinical outcome 2 years after intracoronary administration of bone marrow-derived progenitor cells in acute myocardial infarction

8 July 2018

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A randomized, double-blind, placebo-controlled, dose-escalation study of intravenous adult human mesenchymal stem cells (prochymal) after acute myocardial infarction

8 July 2018

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Noninvasive quantification and optimization of acute cell retention by in vivo positron emission tomography after intramyocardial cardiac-derived stem cell delivery

8 July 2018

1 reference

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Intracoronary infusion of bone marrow-derived mononuclear cells abrogates adverse left ventricular remodelling post-acute myocardial infarction: insights from the reinfusion of enriched progenitor cells and infarct remodelling in acute myocardial in

8 July 2018

1 reference

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Intracoronary bone marrow cell transfer after myocardial infarction: 5-year follow-up from the randomized-controlled BOOST trial

8 July 2018

1 reference

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Engraftment, differentiation, and functional benefits of autologous cardiosphere-derived cells in porcine ischemic cardiomyopathy

8 July 2018

1 reference

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Cardiac progenitor cells and biotinylated insulin-like growth factor-1 nanofibers improve endogenous and exogenous myocardial regeneration after infarction

8 July 2018

1 reference

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Repair of acute myocardial infarction by human stemness factors induced pluripotent stem cells.

8 July 2018

1 reference

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Focused ultrasound-induced stimulation of microbubbles augments site-targeted engraftment of mesenchymal stem cells after acute myocardial infarction

8 July 2018

1 reference

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The BALANCE Study: clinical benefit and long-term outcome after intracoronary autologous bone marrow cell transplantation in patients with acute myocardial infarction

8 July 2018

1 reference

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Long-term myocardial functional improvement after autologous bone marrow mononuclear cells transplantation in patients with ST-segment elevation myocardial infarction: 4 years follow-up

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094549

Intramyocardial bone marrow cell injection for chronic myocardial ischemia: a randomized controlled trial

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094549

Bioengineering to enhance progenitor cell therapeutics

8 July 2018

1 reference

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Stem cells are not proarrhythmic: letting the genie out of the bottle.

8 July 2018

1 reference

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Stem cell therapy is proarrhythmic

8 July 2018

1 reference

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Evidence for cardiomyocyte renewal in humans

8 July 2018

1 reference

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Synergy between CD26/DPP-IV inhibition and G-CSF improves cardiac function after acute myocardial infarction.

8 July 2018

1 reference

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Donor-derived brain tumor following neural stem cell transplantation in an ataxia telangiectasia patient

8 July 2018

1 reference

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Functional cardiomyocytes derived from human induced pluripotent stem cells

8 July 2018

1 reference

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Pulmonary passage is a major obstacle for intravenous stem cell delivery: the pulmonary first-pass effect

8 July 2018

1 reference

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Nuclear reprogramming in cells

8 July 2018

1 reference

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Pharmacological approaches to improve endothelial repair mechanisms

8 July 2018

1 reference

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Immunosuppressive therapy mitigates immunological rejection of human embryonic stem cell xenografts

8 July 2018

1 reference

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Heart failure-related hospitalization in the U.S., 1979 to 2004.

8 July 2018

1 reference

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Assessing identity, phenotype, and fate of endothelial progenitor cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094549

Generation of functional murine cardiac myocytes from induced pluripotent stem cells

8 July 2018

1 reference

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Genetic enhancement of stem cell engraftment, survival, and efficacy

8 July 2018

1 reference

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Engineering robust and functional vascular networks in vivo with human adult and cord blood-derived progenitor cells.

8 July 2018

1 reference

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Autologous bone marrow stem cells to treat acute myocardial infarction: a systematic review

8 July 2018

1 reference

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Ex vivo pretreatment with melatonin improves survival, proangiogenic/mitogenic activity, and efficiency of mesenchymal stem cells injected into ischemic kidney

8 July 2018

1 reference

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Stem cell mobilization by granulocyte colony-stimulating factor for myocardial recovery after acute myocardial infarction: a meta-analysis

8 July 2018

1 reference

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Cell delivery mechanisms for tissue repair

8 July 2018

1 reference

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Stem-cell therapy for cardiac disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094549

The Myoblast Autologous Grafting in Ischemic Cardiomyopathy (MAGIC) trial: first randomized placebo-controlled study of myoblast transplantation.

8 July 2018

1 reference

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Impact of intracoronary cell therapy on left ventricular function in the setting of acute myocardial infarction: a collaborative systematic review and meta-analysis of controlled clinical trials.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094549

8 July 2018

Human cardiac stem cells

1 reference

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Safety analysis and improved cardiac function following local autologous transplantation of CD133(+) enriched bone marrow cells after myocardial infarction

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094549

Adult bone marrow-derived cells for cardiac repair: a systematic review and meta-analysis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094549

Cardiopoietic programming of embryonic stem cells for tumor-free heart repair

8 July 2018

1 reference

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Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

8 July 2018

1 reference

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Improved clinical outcome after intracoronary administration of bone-marrow-derived progenitor cells in acute myocardial infarction: final 1-year results of the REPAIR-AMI trial

8 July 2018

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Transcoronary transplantation of progenitor cells after myocardial infarction

8 July 2018

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Intracoronary Bone Marrow–Derived Progenitor Cells in Acute Myocardial Infarction

8 July 2018

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Intracoronary injection of mononuclear bone marrow cells in acute myocardial infarction

8 July 2018

1 reference

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Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

8 July 2018

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Local myocardial insulin-like growth factor 1 (IGF-1) delivery with biotinylated peptide nanofibers improves cell therapy for myocardial infarction.

8 July 2018

1 reference

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Engineered heart tissue grafts improve systolic and diastolic function in infarcted rat hearts

8 July 2018

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Intracoronary bone marrow cell transfer after myocardial infarction: eighteen months' follow-up data from the randomized, controlled BOOST (BOne marrOw transfer to enhance ST-elevation infarct regeneration) trial

8 July 2018

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Impact of intracoronary bone marrow cell transfer on diastolic function in patients after acute myocardial infarction: results from the BOOST trial

8 July 2018

1 reference

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In vivo visualization of embryonic stem cell survival, proliferation, and migration after cardiac delivery

8 July 2018

1 reference

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Outcomes and risks of granulocyte colony-stimulating factor in patients with coronary artery disease.

8 July 2018

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8 July 2018

1 reference

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Cardiac repair with intramyocardial injection of allogeneic mesenchymal stem cells after myocardial infarction

8 July 2018

1 reference

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8 July 2018

Regenerating the heart

1 reference

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Custom design of the cardiac microenvironment with biomaterials

8 July 2018

1 reference

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Monitoring of bone marrow cell homing into the infarcted human myocardium

8 July 2018

1 reference

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Injectable self-assembling peptide nanofibers create intramyocardial microenvironments for endothelial cells

8 July 2018

1 reference

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Mobilizing endothelial progenitor cells

8 July 2018

1 reference

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Transplantation of progenitor cells and regeneration enhancement in acute myocardial infarction: final one-year results of the TOPCARE-AMI Trial

8 July 2018

1 reference

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Improved exercise capacity and ischemia 6 and 12 months after transendocardial injection of autologous bone marrow mononuclear cells for ischemic cardiomyopathy

8 July 2018

1 reference

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Endothelial progenitor cells: characterization and role in vascular biology

8 July 2018

1 reference

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Intracoronary autologous bone-marrow cell transfer after myocardial infarction: the BOOST randomised controlled clinical trial

8 July 2018

1 reference

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Mesenchymal stem cells and their potential as cardiac therapeutics

8 July 2018

1 reference

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Effects of intracoronary infusion of peripheral blood stem-cells mobilised with granulocyte-colony stimulating factor on left ventricular systolic function and restenosis after coronary stenting in myocardial infarction: the MAGIC cell randomised cl

8 July 2018

1 reference

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Adult cardiac stem cells are multipotent and support myocardial regeneration

8 July 2018

1 reference

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Endothelial progenitor cells: mobilization, differentiation, and homing

8 July 2018

1 reference

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Angiogenesis in ischaemic myocardium by intramyocardial autologous bone marrow mononuclear cell implantation

8 July 2018

1 reference

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Transplantation of Progenitor Cells and Regeneration Enhancement in Acute Myocardial Infarction (TOPCARE-AMI)

8 July 2018

1 reference

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Repair of infarcted myocardium by autologous intracoronary mononuclear bone marrow cell transplantation in humans

8 July 2018

1 reference

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Constitutive human telomerase reverse transcriptase expression enhances regenerative properties of endothelial progenitor cells

8 July 2018

1 reference

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Skeletal muscle stem cells do not transdifferentiate into cardiomyocytes after cardiac grafting

8 July 2018

1 reference

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The inflammatory response in myocardial infarction

8 July 2018

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Local implantation of autologous bone marrow cells for therapeutic angiogenesis in patients with ischemic heart disease: clinical trial and preliminary results

8 July 2018

1 reference

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HMG-CoA reductase inhibitors (statins) increase endothelial progenitor cells via the PI 3-kinase/Akt pathway

8 July 2018

1 reference

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Electromechanical coupling between skeletal and cardiac muscle. Implications for infarct repair

8 July 2018

1 reference

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Isolation of putative progenitor endothelial cells for angiogenesis

8 July 2018

1 reference

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Skeletal myoblast transplantation for repair of myocardial necrosis

8 July 2018

1 reference

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Chronic heart failure in the United States: a manifestation of coronary artery disease

8 July 2018

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Pilot trial on determinants of progenitor cell recruitment to the infarcted human myocardium.

21 January 2018

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Systemic delivery of bone marrow-derived mesenchymal stem cells to the infarcted myocardium: feasibility, cell migration, and body distribution.

21 January 2018

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Assessment of the tissue distribution of transplanted human endothelial progenitor cells by radioactive labeling

21 January 2018

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Experimental and clinical regenerative capability of human bone marrow cells after myocardial infarction.

21 January 2018

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Autologous bone marrow-derived stem-cell transfer in patients with ST-segment elevation myocardial infarction: double-blind, randomised controlled trial

21 January 2018

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Regeneration of human infarcted heart muscle by intracoronary autologous bone marrow cell transplantation in chronic coronary artery disease: the IACT Study.

21 January 2018

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Catheter-based autologous bone marrow myocardial injection in no-option patients with advanced coronary artery disease: a feasibility study

21 January 2018

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Transendocardial, autologous bone marrow cell transplantation for severe, chronic ischemic heart failure

21 January 2018

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Prospective randomized trial of direct endomyocardial implantation of bone marrow cells for treatment of severe coronary artery diseases (PROTECT-CAD trial).

21 January 2018

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Intramyocardial transplantation of autologous CD34+ stem cells for intractable angina: a phase I/IIa double-blind, randomized controlled trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FEURHEARTJ%2FEHR018

Regenerative potential of cardiosphere-derived cells expanded from percutaneous endomyocardial biopsy specimens.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FEURHEARTJ%2FEHR018

Murine "cardiospheres" are not a source of stem cells with cardiomyogenic potential.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FEURHEARTJ%2FEHR018

Evidence for fusion between cardiac and skeletal muscle cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FEURHEARTJ%2FEHR018

Autologous skeletal myoblast transplantation for severe postinfarction left ventricular dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FEURHEARTJ%2FEHR018

Autologous skeletal myoblast transplantation for the treatment of postinfarction myocardial injury: phase I clinical study with 12 months of follow-up.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FEURHEARTJ%2FEHR018

Catheter-based intramyocardial injection of autologous skeletal myoblasts as a primary treatment of ischemic heart failure: clinical experience with six-month follow-up

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FEURHEARTJ%2FEHR018

Safety and feasibility of autologous myoblast transplantation in patients with ischemic cardiomyopathy: four-year follow-up

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FEURHEARTJ%2FEHR018

Percutaneous trans-coronary-venous transplantation of autologous skeletal myoblasts in the treatment of post-infarction myocardial contractility impairment: the POZNAN trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FEURHEARTJ%2FEHR018

Use of granulocyte-colony stimulating factor during acute myocardial infarction to enhance bone marrow stem cell mobilization in humans: clinical and angiographic safety profile.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FEURHEARTJ%2FEHR018

Granulocyte colony-stimulating factor attenuates left ventricular remodelling after acute anterior STEMI: results of the single-blind, randomized, placebo-controlled multicentre STem cEll Mobilization in Acute Myocardial Infarction (STEM-AMI) Trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FEURHEARTJ%2FEHR018

Stimulation of paracrine pathways with growth factors enhances embryonic stem cell engraftment and host-specific differentiation in the heart after ischemic myocardial injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FEURHEARTJ%2FEHR018

HMG-CoA reductase inhibitors reduce senescence and increase proliferation of endothelial progenitor cells via regulation of cell cycle regulatory genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FEURHEARTJ%2FEHR018

Increase in circulating endothelial progenitor cells by statin therapy in patients with stable coronary artery disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FEURHEARTJ%2FEHR018

Stimulation of endothelial progenitor cells: a new putative therapeutic effect of angiotensin II receptor antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FEURHEARTJ%2FEHR018

Pre-treatment of mesenchymal stem cells with a combination of growth factors enhances gap junction formation, cytoprotective effect on cardiomyocytes, and therapeutic efficacy for myocardial infarction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FEURHEARTJ%2FEHR018

Local delivery of protease-resistant stromal cell derived factor-1 for stem cell recruitment after myocardial infarction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FEURHEARTJ%2FEHR018

Myocardium-targeted delivery of endothelial progenitor cells by ultrasound-mediated microbubble destruction improves cardiac function via an angiogenic response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FEURHEARTJ%2FEHR018

Intracoronary transplantation of autologous bone marrow mesenchymal stem cells for ischemic cardiomyopathy due to isolated chronic occluded left anterior descending artery.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094549

Intracoronary injection of CD133-positive enriched bone marrow progenitor cells promotes cardiac recovery after recent myocardial infarction: feasibility and safety

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094549

Autologous human serum for cell culture avoids the implantation of cardioverter-defibrillators in cellular cardiomyoplasty

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3094549

The consensus of the task force of the European Society of Cardiology concerning the clinical investigation of the use of autologous adult stem cells for repair of the heart

26 October 2018

1 reference

https://api.crossref.org/works/10.1093%2FEURHEARTJ%2FEHR018

Autologous bone-marrow stem-cell transplantation for myocardial regeneration

21 January 2018

1 reference

12 December 2020

Stromal cell-derived factor-1 effects on ex vivo expanded endothelial progenitor cell recruitment for ischemic neovascularization

1 reference

12 December 2020

Autologous intramyocardial injection of cultured skeletal muscle-derived stem cells in patients with non-acute myocardial infarction

1 reference

12 December 2020

CABG and bone marrow stem cell transplantation after myocardial infarction

1 reference

12 December 2020

Effect on left ventricular function of intracoronary transplantation of autologous bone marrow mesenchymal stem cell in patients with acute myocardial infarction

1 reference

12 December 2020

CD34-positive cells exhibit increased potency and safety for therapeutic neovascularization after myocardial infarction compared with total mononuclear cells

1 reference

12 December 2020

Pretreatment of adult bone marrow mesenchymal stem cells with cardiomyogenic growth factors and repair of the chronically infarcted myocardium

1 reference

12 December 2020

Although pig allogeneic mesenchymal stem cells are not immunogenic in vitro, intracardiac injection elicits an immune response in vivo

1 reference

12 December 2020

Oxidant stress impairs in vivo reendothelialization capacity of endothelial progenitor cells from patients with type 2 diabetes mellitus: restoration by the peroxisome proliferator-activated receptor-gamma agonist rosiglitazone

1 reference

12 December 2020

STAT3-dependent mouse embryonic stem cell differentiation into cardiomyocytes: analysis of molecular signaling and therapeutic efficacy of cardiomyocyte precommitted mES transplantation in a mouse model of myocardial infarction

1 reference

12 December 2020

Time-Dependent Effects on Coronary Remodeling and Epicardial Conductance after Intracoronary Injection of Enriched Hematopoietic Bone Marrow Stem Cells in Patients with Previous Myocardial Infarction

1 reference

12 December 2020

Intracoronary infusion of bone marrow-derived selected CD34+CXCR4+ cells and non-selected mononuclear cells in patients with acute STEMI and reduced left ventricular ejection fraction: results of randomized, multicentre Myocardial Regeneration by Int

1 reference

12 December 2020

Bone marrow cell therapy after myocardial infarction. What should we select?

1 reference

12 December 2020

Rationale and design of Enhanced Angiogenic Cell Therapy in Acute Myocardial Infarction (ENACT-AMI): The first randomized placebo-controlled trial of enhanced progenitor cell therapy for acute myocardial infarction

1 reference

12 December 2020

Impaired endothelial repair capacity of early endothelial progenitor cells in prehypertension: relation to endothelial dysfunction

1 reference

12 December 2020

Illuminating the potential of pluripotent stem cells

1 reference

12 December 2020

Effect of external oxygen mass transfer resistances on viability of immunoisolated tissue

1 reference

12 December 2020

Regenerating functional myocardium: Improved performance after skeletal myoblast transplantation

1 reference

12 December 2020

Identifiers

DOI

10.1093/EURHEARTJ/EHR018

1 reference

5 August 2017

1 reference

5 August 2017

1 reference

PubMed ID

21362705