Benefit of farnesoid X receptor inhibition in obstructive cholestasis (Q34983994)

5 August 2017

Benefit of farnesoid X receptor inhibition in obstructive cholestasis (English)

1 reference

5 August 2017

6

Ronald M Evans

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Catherine Stedman

1

object named as

Catherine Stedman

1 reference

5 August 2017

Christopher Liddle

2

1 reference

5 August 2017

Sally Coulter

3

1 reference

5 August 2017

Junichiro Sonoda

4

1 reference

5 August 2017

Jacqueline G Alvarez

5

1 reference

5 August 2017

Michael Downes

7

1 reference

5 August 2017

language of work or name

English

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publication date

14 July 2006

1 reference

Proceedings of the National Academy of Sciences of the United States of America

5 August 2017

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5 August 2017

103

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5 August 2017

30

1 reference

5 August 2017

11323-11328

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Substrate specificity of human ABCC4 (MRP4)-mediated cotransport of bile acids and reduced glutathione

5 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1544085

Nuclear receptors constitutive androstane receptor and pregnane X receptor ameliorate cholestatic liver injury

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1544085

Expression of ABCG5 and ABCG8 is required for regulation of biliary cholesterol secretion

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1544085

The farnesoid X receptor induces very low density lipoprotein receptor gene expression

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1544085

Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1544085

Peroxisome proliferator-activated receptor-gamma coactivator 1alpha (PGC-1alpha) regulates triglyceride metabolism by activation of the nuclear receptor FXR

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1544085

Hepatoprotection by the farnesoid X receptor agonist GW4064 in rat models of intra- and extrahepatic cholestasis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1544085

Farnesoid X Receptor Activates Transcription of the Phospholipid Pump MDR3

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1544085

A chemical, genetic, and structural analysis of the nuclear bile acid receptor FXR

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1544085

The Human Apolipoprotein AV Gene Is Regulated by Peroxisome Proliferator-activated Receptor-α and Contains a Novel Farnesoid X-activated Receptor Response Element

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1544085

Regulation of Drug Transporter Gene Expression by Nuclear Receptors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1544085

The enzymes, regulation, and genetics of bile acid synthesis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1544085

Regulation of a xenobiotic sulfonation cascade by nuclear pregnane X receptor (PXR).

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1544085

An apolipoprotein influencing triglycerides in humans and mice revealed by comparative sequencing

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1544085

The lipemia of sepsis: triglyceride-rich lipoproteins as agents of innate immunity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1544085

The orphan nuclear receptor SXR coordinately regulates drug metabolism and efflux

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1544085

An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1544085

Humanized xenobiotic response in mice expressing nuclear receptor SXR.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1544085

Catabolites of cholesterol synthesis pathways and forskolin as activators of the farnesoid X-activated nuclear receptor

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1544085

Bile acids: natural ligands for an orphan nuclear receptor

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1544085

Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis.

8 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0604772103

Conclusive evidence of endotoxaemia in biliary obstruction

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0604772103

Acute inflammation and infection maintain circulating phospholipid levels and enhance lipopolysaccharide binding to plasma lipoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0604772103

Feed-forward regulation of bile acid detoxification by CYP3A4: studies in humanized transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0604772103

Role of farnesoid X receptor in determining hepatic ABC transporter expression and liver injury in bile duct-ligated mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0604772103

Adaptive changes in hepatobiliary transporter expression in primary biliary cirrhosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0604772103

ApoAV reduces plasma triglycerides by inhibiting very low density lipoprotein-triglyceride (VLDL-TG) production and stimulating lipoprotein lipase-mediated VLDL-TG hydrolysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0604772103

Fxr(-/-) mice adapt to biliary obstruction by enhanced phase I detoxification and renal elimination of bile acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0604772103

Protective effects of 6-ethyl chenodeoxycholic acid, a farnesoid X receptor ligand, in estrogen-induced cholestasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0604772103

Complementary stimulation of hepatobiliary transport and detoxification systems by rifampicin and ursodeoxycholic acid in humans

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1544085

Effect of bile acids on endotoxin in vitro and in vivo (physico-chemical defense). Bile deficiency and endotoxin translocation

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16844773

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0604772103

1 reference

5 August 2017

0 references

1 reference

5 August 2017

1 reference