Active-site structure of a β-hydroxylase in antibiotic biosynthesis (Q34985898)

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29 January 2020

title

Active-site structure of a β-hydroxylase in antibiotic biosynthesis (English)

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29 January 2020

1

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29 January 2020

Thomas Makris

series ordinal

2

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29 January 2020

John D. Lipscomb

series ordinal

3

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29 January 2020

author name string

Lawrence Que

series ordinal

4

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29 January 2020

language of work or name

English

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publication date

20 April 2011

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Journal of the American Chemical Society

29 January 2020

published in

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29 January 2020

volume

133

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29 January 2020

issue

18

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29 January 2020

page(s)

6938-6941

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A family of diiron monooxygenases catalyzing amino acid beta-hydroxylation in antibiotic biosynthesis

29 January 2020

cites work

1 reference

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A diiron(IV) complex that cleaves strong C-H and O-H bonds

8 July 2018

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A long-lived, substrate-hydroxylating peroxodiiron(III/III) intermediate in the amine oxygenase, AurF, from Streptomyces thioluteus

8 July 2018

1 reference

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Stereospecific synthesis of threo- and erythro-beta-hydroxyglutamic acid during kutzneride biosynthesis

8 July 2018

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Spectroscopy and kinetics of wild-type and mutant tyrosine hydroxylase: mechanistic insight into O2 activation

8 July 2018

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Spectroscopic and computational studies of (mu-oxo)(mu-1,2-peroxo)diiron(III) complexes of relevance to nonheme diiron oxygenase intermediates

8 July 2018

1 reference

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In vitro reconstitution and crystal structure of p-aminobenzoate N-oxygenase (AurF) involved in aureothin biosynthesis

8 July 2018

1 reference

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Intermediates in dioxygen activation by methane monooxygenase: a QM/MM study

8 July 2018

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Crystal structure of a substrate complex of myo-inositol oxygenase, a di-iron oxygenase with a key role in inositol metabolism

8 July 2018

1 reference

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Evidence for C-H cleavage by an iron-superoxide complex in the glycol cleavage reaction catalyzed by myo-inositol oxygenase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3096070

2.0A resolution crystal structures of the ternary complexes of human phenylalanine hydroxylase catalytic domain with tetrahydrobiopterin and 3-(2-thienyl)-L-alanine or L-norleucine...

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3096070

Assembling the glycopeptide antibiotic scaffold: The biosynthesis of A47934 from Streptomyces toyocaensis NRRL15009

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3096070

Synthesis and spectroscopic studies of non-heme diiron(III) species with a terminal hydroperoxide ligand: models for hemerythrin.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3096070

Coumarin formation in novobiocin biosynthesis: beta-hydroxylation of the aminoacyl enzyme tyrosyl-S-NovH by a cytochrome P450 NovI

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3096070

The biosynthetic gene cluster for the antitumor drug bleomycin from Streptomyces verticillus ATCC15003 supporting functional interactions between nonribosomal peptide synthetases and a polyketide synthase

8 July 2018

1 reference

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Structure and function of the Escherichia coli ribonucleotide reductase protein R2

8 July 2018

1 reference

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Extended X-ray absorption fine structure studies on the iron-containing subunit of ribonucleotide reductase from Escherichia coli

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3096070

Comparative Fe and Zn K-edge X-ray absorption spectroscopic study of the ferroxidase centres of human H-chain ferritin and bacterioferritin from Desulfovibrio desulfuricans.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3096070

Determination by X-ray absorption spectroscopy of the Fe-Fe separation in the oxidized form of the hydroxylase of methane monooxygenase alone and in the presence of MMOD.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3096070

Aminoacyl-S-enzyme intermediates in beta-hydroxylations and alpha,beta-desaturations of amino acids in peptide antibiotics

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3096070

Dioxygen Activation by Enzymes Containing Binuclear Non-Heme Iron Clusters

26 October 2018

1 reference

12 December 2020

Correlating structure with function in bacterial multicomponent monooxygenases and related diiron proteins

1 reference

12 December 2020

An asparagine oxygenase (AsnO) and a 3-hydroxyasparaginyl phosphotransferase (HasP) are involved in the biosynthesis of calcium-dependent lipopeptide antibiotics

1 reference

12 December 2020

An EXAFS study of the interaction of substrate with the ferric active site of protocatechuate 3,4-dioxygenase

1 reference

12 December 2020

Raman spectral evidence for a .mu.-oxo bridge in the binuclear iron center of ribonucleotide reductase

1 reference

12 December 2020

Ramoplanin (A-16686), a new glycolipodepsipeptide antibiotic. III. Structure elucidation

1 reference

12 December 2020

The active site of hemerythrin as determined by X-ray absorption fine structure

1 reference

12 December 2020

An Fe2IVO2 Diamond Core Structure for the Key Intermediate Q of Methane Monooxygenase

1 reference

12 December 2020

Identifiers

DOI

10.1021/JA201822V

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29 January 2020

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29 January 2020

PubMed publication ID

21506543

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