Stabilization of atherosclerotic plaques: new mechanisms and clinical targets (Q34986368)

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English	Stabilization of atherosclerotic plaques: new mechanisms and clinical targets	scientific article

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scholarly article

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Europe PubMed Central

5 August 2017

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Europe PubMed Central

Stabilization of atherosclerotic plaques: new mechanisms and clinical targets (English)

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Europe PubMed Central

5 August 2017

atherosclerosis

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based on heuristic

inferred from title

1

object named as

Peter Libby

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Europe PubMed Central

5 August 2017

Masanori Aikawa

2

object named as

Masanori Aikawa

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Europe PubMed Central

5 August 2017

language of work or name

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publication date

1 November 2002

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Europe PubMed Central

5 August 2017

Nature Medicine

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Europe PubMed Central

5 August 2017

8

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Europe PubMed Central

5 August 2017

11

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Europe PubMed Central

5 August 2017

1257-1262

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Europe PubMed Central

5 August 2017

https://scigraph.springernature.com/pub.10.1038/nm1102-1257

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Coronary plaque disruption.

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

21 January 2018

Risk-reduction therapy: the challenge to change. Presented at the 68th scientific sessions of the American Heart Association November 13, 1995 Anaheim, California

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

21 January 2018

Coronary plaque erosion without rupture into a lipid core. A frequent cause of coronary thrombosis in sudden coronary death

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

21 January 2018

Stability and instability: two faces of coronary atherosclerosis. The Paul Dudley White Lecture 1995.

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

21 January 2018

Molecular bases of the acute coronary syndromes

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

21 January 2018

IFN-gamma potentiates atherosclerosis in ApoE knock-out mice

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

21 January 2018

Vulnerable atherosclerotic plaque morphology in apolipoprotein E-deficient mice unable to make ascorbic Acid

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

21 January 2018

Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

21 January 2018

Localization of stromelysin gene expression in atherosclerotic plaques by in situ hybridization

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

21 January 2018

Production of tissue collagenase (matrix metalloproteinase 1) by human aortic smooth muscle cells in response to platelet-derived growth factor

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

21 January 2018

Cytokine-stimulated human vascular smooth muscle cells synthesize a complement of enzymes required for extracellular matrix digestion

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

21 January 2018

Reactive oxygen species produced by macrophage-derived foam cells regulate the activity of vascular matrix metalloproteinases in vitro. Implications for atherosclerotic plaque stability

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

21 January 2018

Risk of thrombosis in human atherosclerotic plaques: role of extracellular lipid, macrophage, and smooth muscle cell content

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

21 January 2018

Localization of tissue factor in the normal vessel wall and in the atherosclerotic plaque

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

21 January 2018

Activation of monocyte/macrophage functions related to acute atheroma complication by ligation of CD40: induction of collagenase, stromelysin, and tissue factor.

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

21 January 2018

Lipid lowering and plaque regression. New insights into prevention of plaque disruption and clinical events in coronary disease

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

21 January 2018

Lipid lowering by diet reduces matrix metalloproteinase activity and increases collagen content of rabbit atheroma: a potential mechanism of lesion stabilization.

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

21 January 2018

Lipid lowering reduces oxidative stress and endothelial cell activation in rabbit atheroma

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

21 January 2018

Pravastatin treatment increases collagen content and decreases lipid content, inflammation, metalloproteinases, and cell death in human carotid plaques: implications for plaque stabilization

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

21 January 2018

Dietary lipid lowering reduces tissue factor expression in rabbit atheroma.

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

21 January 2018

An HMG-CoA reductase inhibitor, cerivastatin, suppresses growth of macrophages expressing matrix metalloproteinases and tissue factor in vivo and in vitro

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

21 January 2018

Pleiotropic effects of statins: do they matter?

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

21 January 2018

Stroke protection by 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors mediated by endothelial nitric oxide synthase

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

21 January 2018

In vivo anti-inflammatory effect of statins is mediated by nonsterol mevalonate products

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

21 January 2018

Simvastatin has anti-inflammatory and antiatherosclerotic activities independent of plasma cholesterol lowering

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

21 January 2018

Simvastatin preserves coronary endothelial function in hypercholesterolemia in the absence of lipid lowering

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

21 January 2018

Upregulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

21 January 2018

Effects of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors, atorvastatin and simvastatin, on the expression of endothelin-1 and endothelial nitric oxide synthase in vascular endothelial cells

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

21 January 2018

The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

21 January 2018

Statins have biphasic effects on angiogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

21 January 2018

Double-edged role of statins in angiogenesis signaling

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

21 January 2018

Statin therapy accelerates reendothelialization: a novel effect involving mobilization and incorporation of bone marrow-derived endothelial progenitor cells

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

21 January 2018

Simvastatin preserves the structure of coronary adventitial vasa vasorum in experimental hypercholesterolemia independent of lipid lowering

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

21 January 2018

Human smooth muscle myosin heavy chain isoforms as molecular markers for vascular development and atherosclerosis

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

21 January 2018

Distinct patterns of expression of fibroblast growth factors and their receptors in human atheroma and nonatherosclerotic arteries. Association of acidic FGF with plaque microvessels and macrophages

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

21 January 2018

Angiogenesis in cancer and other diseases

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

21 January 2018

Angiogenesis inhibitors endostatin or TNP-470 reduce intimal neovascularization and plaque growth in apolipoprotein E-deficient mice.

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

21 January 2018

Vascular endothelial growth factor enhances atherosclerotic plaque progression

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

21 January 2018

PPARalpha activators inhibit cytokine-induced vascular cell adhesion molecule-1 expression in human endothelial cells

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

21 January 2018

PPARalpha activators inhibit tissue factor expression and activity in human monocytes

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

21 January 2018

PPARalpha agonists inhibit tissue factor expression in human monocytes and macrophages

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

21 January 2018

PPAR activators as antiinflammatory mediators in human T lymphocytes: implications for atherosclerosis and transplantation-associated arteriosclerosis

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

21 January 2018

Peroxisome proliferator-activated receptor gamma ligands inhibit development of atherosclerosis in LDL receptor-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

21 January 2018

Troglitazone inhibits atherosclerosis in apolipoprotein E-knockout mice: pleiotropic effects on CD36 expression and HDL.

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

21 January 2018

The coxibs, selective inhibitors of cyclooxygenase-2.

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

21 January 2018

Inhibition of CD40 signaling limits evolution of established atherosclerosis in mice

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

21 January 2018

Requirement for CD154 in the progression of atherosclerosis.

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

21 January 2018

Effect of atorvastatin and fluvastatin on the expression of plasminogen activator inhibitor type-1 in cultured human endothelial cells

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

21 January 2018

Pre-existing coronary stenoses in patients with first myocardial infarction are not necessarily severe

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

7 January 2021

based on heuristic

inferred from DOI database lookup

Cytokines and growth factors positively and negatively regulate interstitial collagen gene expression in human vascular smooth muscle cells.

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

7 January 2021

based on heuristic

inferred from DOI database lookup

Interstitial collagenase (MMP-1) expression in human carotid atherosclerosis

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

7 January 2021

based on heuristic

inferred from DOI database lookup

Evidence for increased collagenolysis by interstitial collagenases-1 and -3 in vulnerable human atheromatous plaques

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

7 January 2021

based on heuristic

inferred from DOI database lookup

Expression of neutrophil collagenase (matrix metalloproteinase-8) in human atheroma: a novel collagenolytic pathway suggested by transcriptional profiling

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

7 January 2021

based on heuristic

inferred from DOI database lookup

Site of intimal rupture or erosion of thrombosed coronary atherosclerotic plaques is characterized by an inflammatory process irrespective of the dominant plaque morphology

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

7 January 2021

based on heuristic

inferred from DOI database lookup

Cell composition, replication, and apoptosis in atherosclerotic plaques after 6 months of cholesterol withdrawal

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

7 January 2021

based on heuristic

inferred from DOI database lookup

HMG-CoA reductase inhibition by atorvastatin reduces neointimal inflammation in a rabbit model of atherosclerosis

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

7 January 2021

based on heuristic

inferred from DOI database lookup

The ACAT inhibitor avasimibe reduces macrophages and matrix metalloproteinase expression in atherosclerotic lesions of hypercholesterolemic rabbits

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

7 January 2021

based on heuristic

inferred from DOI database lookup

Reduction in serum cholesterol with pravastatin improves endothelium-dependent coronary vasomotion in patients with hypercholesterolemia

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

7 January 2021

based on heuristic

inferred from DOI database lookup

Beneficial effects of cholesterol-lowering therapy on the coronary endothelium in patients with coronary artery disease

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

7 January 2021

based on heuristic

inferred from DOI database lookup

HMG CoA reductase inhibitors reduce plasminogen activator inhibitor-1 expression by human vascular smooth muscle and endothelial cells

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

7 January 2021

based on heuristic

inferred from DOI database lookup

Angiotensin-converting enzyme inhibition prevents arterial nuclear factor-kappa B activation, monocyte chemoattractant protein-1 expression, and macrophage infiltration in a rabbit model of early accelerated atherosclerosis

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

7 January 2021

based on heuristic

inferred from DOI database lookup

Aldosterone: a mediator of myocardial necrosis and renal arteriopathy

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

7 January 2021

based on heuristic

inferred from DOI database lookup

Troglitazone inhibits formation of early atherosclerotic lesions in diabetic and nondiabetic low density lipoprotein receptor-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FNM1102-1257

7 January 2021

based on heuristic

inferred from DOI database lookup

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10.1038/NM1102-1257

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Europe PubMed Central

5 August 2017

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Europe PubMed Central

5 August 2017

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