The tumor necrosis factor family member LIGHT is a target for asthmatic airway remodeling (Q34989767)

5 August 2017

The tumor necrosis factor family member LIGHT is a target for asthmatic airway remodeling (English)

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5 August 2017

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Stefanie Scheu

9

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Taylor A Doherty

object named as

Taylor A Doherty

1

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Klaus Pfeffer

object named as

Klaus Pfeffer

10

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author name string

Pejman Soroosh

2

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5 August 2017

Naseem Khorram

3

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5 August 2017

Satoshi Fukuyama

4

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5 August 2017

Peter Rosenthal

5

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5 August 2017

Jae Youn Cho

6

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5 August 2017

Paula S Norris

7

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5 August 2017

Heonsik Choi

8

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5 August 2017

Bruce L Zuraw

11

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5 August 2017

Carl F Ware

12

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5 August 2017

David H Broide

13

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5 August 2017

Michael Croft

14

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5 August 2017

language of work or name

English

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publication date

17 April 2011

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5 August 2017

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5 August 2017

17

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5 August 2017

5

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5 August 2017

596-603

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https://scigraph.springernature.com/pub.10.1038/nm.2356

5 August 2017

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cites work

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8 July 2018

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Role of transforming growth factor-β in airway remodeling in asthma

8 July 2018

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Analyses of asthma severity phenotypes and inflammatory proteins in subjects stratified by sputum granulocytes

8 July 2018

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TGF-beta1 induced epithelial to mesenchymal transition (EMT) in human bronchial epithelial cells is enhanced by IL-1beta but not abrogated by corticosteroids.

8 July 2018

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T-helper type 2-driven inflammation defines major subphenotypes of asthma.

8 July 2018

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Concurrent dual allergen exposure and its effects on airway hyperresponsiveness, inflammation and remodeling in mice

8 July 2018

1 reference

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House dust mite allergen induces asthma via Toll-like receptor 4 triggering of airway structural cells

8 July 2018

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Transcriptome profiling of primary murine monocytes, lung macrophages and lung dendritic cells reveals a distinct expression of genes involved in cell trafficking

8 July 2018

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Where asthma and hypersensitivity pneumonitis meet and differ: noneosinophilic severe asthma

8 July 2018

1 reference

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CD4+ cells are required for chronic eosinophilic lung inflammation but not airway remodeling

8 July 2018

1 reference

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The inhibitory HVEM-BTLA pathway counter regulates lymphotoxin receptor signaling to achieve homeostasis of dendritic cells

8 July 2018

1 reference

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In vivo blockade of OX40 ligand inhibits thymic stromal lymphopoietin driven atopic inflammation

8 July 2018

1 reference

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Detection and quantitation of eosinophils in the murine respiratory tract by flow cytometry

8 July 2018

1 reference

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IL-13-induced proliferation of airway epithelial cells: mediation by intracellular growth factor mobilization and ADAM17

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097134

Expression of lymphotoxin-alphabeta on antigen-specific T cells is required for DC function

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097134

Network communications: lymphotoxins, LIGHT, and TNF.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097134

Inhibition of airway remodeling in IL-5-deficient mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097134

Anti-IL-5 treatment reduces deposition of ECM proteins in the bronchial subepithelial basement membrane of mild atopic asthmatics

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097134

Tryptase-stimulated human airway smooth muscle cells induce cytokine synthesis and mast cell chemotaxis

8 July 2018

1 reference

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OX40 (CD134) controls memory T helper 2 cells that drive lung inflammation

8 July 2018

1 reference

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CysLT1 receptor upregulation by TGF-β and IL-13 is associated with bronchial smooth muscle cell proliferation in response to LTD4

8 July 2018

1 reference

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Role of matrix metalloproteinases in asthma

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097134

Targeted disruption of LIGHT causes defects in costimulatory T cell activation and reveals cooperation with lymphotoxin beta in mesenteric lymph node genesis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097134

Macrophages and the pathogenesis of COPD.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097134

Tumor necrosis factor receptor superfamily 14 is involved in atherogenesis by inducing proinflammatory cytokines and matrix metalloproteinases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097134

LIGHT, a member of the TNF superfamily, induces morphological changes and delays proliferation in the human rhabdomyosarcoma cell line RD.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097134

Inducible expression of inflammatory chemokines in respiratory syncytial virus-infected mice: role of MIP-1alpha in lung pathology

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097134

8 July 2018

1 reference

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Expression of three members of the TNF-R family of receptors (4-1BB, lymphotoxin-beta receptor, and Fas) in human lung

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097134

LIGHT, a new member of the TNF superfamily, and lymphotoxin alpha are ligands for herpesvirus entry mediator

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097134

Regulation of alveolar macrophage transforming growth factor-beta secretion by corticosteroids in bleomycin-induced pulmonary inflammation in the rat.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097134

Effects of treatment on airway inflammation and thickening of basement membrane reticular collagen in asthma. A quantitative light and electron microscopic study

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097134

Eosinophils are dispensable for allergic remodeling and immunity in a model of house dust mite-induced airway disease.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097134

Airway remodeling in subjects with severe asthma with or without chronic persistent airflow obstruction.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097134

Relative corticosteroid insensitivity of alveolar macrophages in severe asthma compared with non-severe asthma

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097134

Transforming growth factor-beta regulates house dust mite-induced allergic airway inflammation but not airway remodeling.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097134

Inhibition of allergen-induced airway remodeling in Smad 3-deficient mice.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097134

Inhibition of arginase I activity by RNA interference attenuates IL-13-induced airways hyperresponsiveness

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097134

Reduced peribronchial fibrosis in allergen-challenged MMP-9-deficient mice.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097134

Oral CD3-specific antibody suppresses autoimmune encephalomyelitis by inducing CD4+ CD25- LAP+ T cells.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097134

Evidence of a role of tumor necrosis factor alpha in refractory asthma

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097134

Inhibition of chronic airway inflammation and remodeling by galectin-3 gene therapy in a murine model

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097134

LIGHT enhances the bactericidal activity of human monocytes and neutrophils via HVEM.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097134

Differences in airway remodeling between subjects with severe and moderate asthma.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097134

Anti-IL-13 monoclonal antibody inhibits airway hyperresponsiveness, inflammation and airway remodeling

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097134

Interleukin-13 in asthma pathogenesis.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097134

A critical role for eosinophils in allergic airways remodeling.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097134

Immunostimulatory DNA Inhibits Transforming Growth Factor-β Expression and Airway Remodeling

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097134

Potential Action of IL-4 and IL-13 as Fibrogenic Factors on Lung Fibroblasts in vitro

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097134

Continuous exposure to house dust mite elicits chronic airway inflammation and structural remodeling

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097134

Airway remodeling-associated mediators in moderate to severe asthma: effect of steroids on TGF-beta, IL-11, IL-17, and type I and type III collagen expression

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097134

Interleukin-13 augments transforming growth factor-beta1-induced tissue inhibitor of metalloproteinase-1 expression in primary human airway fibroblasts

26 October 2018

1 reference

12 December 2020

Manipulation of allergen-induced airway remodeling by treatment with anti-TGF-beta antibody: effect on the Smad signaling pathway

1 reference

12 December 2020

Signaling pathways of LIGHT induced macrophage migration and vascular smooth muscle cell proliferation

1 reference

12 December 2020

Cutting Edge: Immature human dendritic cells express latency-associated peptide and inhibit T cell activation in a TGF-beta-dependent manner

1 reference

12 December 2020

Components of airway hyperresponsiveness and their associations with inflammation and remodeling in mice

1 reference

12 December 2020

Airway hyperresponsiveness, inflammation, and subepithelial collagen deposition in recently diagnosed versus long-standing mild asthma. Influence of inhaled corticosteroids

1 reference

12 December 2020

Therapeutic effect of IL-13 immunoneutralization during chronic experimental fungal asthma

1 reference

12 December 2020

Occurrence of an activated, profibrotic pattern of gene expression in lung CD8+ T cells from scleroderma patients

1 reference

12 December 2020

Identifiers

DOI

10.1038/NM.2356

1 reference

5 August 2017

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5 August 2017

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