Is polyproline II a major backbone conformation in unfolded proteins? (Q34989900)

5 August 2017

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title

Is polyproline II a major backbone conformation in unfolded proteins? (English)

1 reference

5 August 2017

Zhengshuang Shi

1

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5 August 2017

Robert W Woody

series ordinal

2

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5 August 2017

Neville R Kallenbach

series ordinal

3

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5 August 2017

publication date

1 January 2002

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Advances in Protein Chemistry

5 August 2017

published in

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5 August 2017

volume

62

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5 August 2017

page(s)

163-240

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Refined structure of baboon α-lactalbumin at 1.7 Å resolution

5 August 2017

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Left-handed polyproline II helices commonly occur in globular proteins.

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Conservation of polyproline II helices in homologous proteins: implications for structure prediction by model building

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Extensive homology among the largest subunits of eukaryotic and prokaryotic RNA polymerases

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Microfolding: Conformational probability map for the alanine dipeptide in water from molecular dynamics simulations

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Rapid formation of a molten globule intermediate in refolding of alpha-lactalbumin

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7 January 2021

Role of the molten globule state in protein folding.

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A comparison of the pH, urea, and temperature-denatured states of barnase by heteronuclear NMR: implications for the initiation of protein folding

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Structural and dynamic characterization of an unfolded state of poplar apo-plastocyanin formed under nondenaturing conditions

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Protein folding monitored at individual residues during a two-dimensional NMR experiment

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7 January 2021

Following protein folding in real time using NMR spectroscopy

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7 January 2021

Solution structure and dynamics of biomolecules from Raman optical activity.

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7 January 2021

Characterization of a partly folded protein by NMR methods: studies on the molten globule state of guinea pig alpha-lactalbumin

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7 January 2021

Crystal structure of a collagen-like polypeptide with repeating sequence Pro-Hyp-Gly at 1.4 A resolution: implications for collagen hydration

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7 January 2021

Functional consequences of preorganized helical structure in the intrinsically disordered cell-cycle inhibitor p27(Kip1).

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7 January 2021

Conformation of the RNA polymerase II C-terminal domain: circular dichroism of long and short fragments.

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7 January 2021

Is polyproline II helix the killer conformation? a raman optical activity study of the amyloidogenic prefibrillar intermediate of human lysozyme 1 1Edited by A. R. Fersht

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Folding of Protein G B1 Domain Studied by the Conformational Characterization of Fragments Comprising Its Secondary Structure Elements

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Solvent-induced distortions and the curvature of alpha-helices

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Sequence-Corrected 15N "Random Coil" Chemical Shifts

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7 January 2021

Structural studies of a synthetic peptide derived from the carboxyl-terminal domain of RNA polymerase II.

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7 January 2021

Intrinsic structural disorder of the C-terminal activation domain from the bZIP transcription factor Fos

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7 January 2021

A possible initial folding intermediate: the C-terminal proteolytic domain of tryptophan synthase beta chains folds in less than 4 milliseconds into a condensed state with non-native-like secondary structure

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7 January 2021

Kinetic resolution of peptide bond and side chain far-UV circular dichroism during the folding of hen egg white lysozyme

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7 January 2021

Comparison of equilibrium and kinetic approaches for determining protein folding mechanisms

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7 January 2021

Yeast heat shock transcription factor N-terminal activation domains are unstructured as probed by heteronuclear NMR spectroscopy

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7 January 2021

Structure and stability of the molten globule state of guinea-pig alpha-lactalbumin: a hydrogen exchange study

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7 January 2021

Structure of Poly-L-Proline

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7 January 2021

Structure of the acid state of Escherichia coli ribonuclease HI.

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7 January 2021

Denatured states of proteins

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7 January 2021

Comment on the Communication "The Key to Solving the Protein-Folding Problem Lies in an Accurate Description of the Denatured State" by van Gunsteren et al. We thank Eugene Shakhnovich (Harvard University) for pointing out the references on lattice

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7 January 2021

Compact state of a protein molecule with pronounced small-scale mobility: bovine alpha-lactalbumin

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7 January 2021

Reassessment of the electronic circular dichroism criteria for random coil conformations of poly(L-lysine) and the implications for protein folding and denaturation studies

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7 January 2021

Reassessment of the random coil conformation: vibrational CD study of proline oligopeptides and related polypeptides

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7 January 2021

Intrinsically disordered protein

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7 January 2021

Folding of peptide fragments comprising the complete sequence of proteins. Models for initiation of protein folding. I. Myohemerythrin

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7 January 2021

Folding of immunogenic peptide fragments of proteins in water solution. II. The nascent helix

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7 January 2021

Nuclear magnetic resonance methods for elucidation of structure and dynamics in disordered states

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7 January 2021

Insights into the structure and dynamics of unfolded proteins from nuclear magnetic resonance

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7 January 2021

Structural and dynamic characterization of partially folded states of apomyoglobin and implications for protein folding

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7 January 2021

Early steps in cytochrome c folding probed by time-resolved circular dichroism and fluorescence spectroscopy

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7 January 2021

Refined structure of bovine carbonic anhydrase III at 2.0 A resolution

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7 January 2021

Circular dichroism of polypeptide and protein conformations. Film studies

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7 January 2021

Toward a Description of the Conformations of Denatured States of Proteins. Comparison of a Random Coil Model with NMR Measurements

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7 January 2021

Compact intermediate states in protein folding.

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7 January 2021

Classification of acid denaturation of proteins: intermediates and unfolded states

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7 January 2021

Assignment of the contribution of the tryptophan residues to the circular dichroism spectrum of human carbonic anhydrase II.

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7 January 2021

Prothymosin alpha: a biologically active protein with random coil conformation.

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7 January 2021

Expression and characterisation of a highly repetitive peptide derived from a wheat seed storage protein

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7 January 2021

Characterization of long-range structure in the denatured state of staphylococcal nuclease. II. Distance restraints from paramagnetic relaxation and calculation of an ensemble of structures

1 reference

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7 January 2021

An early immunoreactive folding intermediate of the tryptophan synthease beta 2 subunit is a 'molten globule'.

1 reference

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7 January 2021

Conformational states of beta-lactamase: molten-globule states at acidic and alkaline pH with high salt

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https://api.crossref.org/works/10.1016%2FS0065-3233%2802%2962008-X

7 January 2021

Mechanism of acid-induced folding of proteins

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7 January 2021

Ab initio self-consistent field and potential-dependent partial equalization of orbital electronegativity calculations of hydration properties of N-acetyl-N'-methyl-alanineamide

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7 January 2021

Computed circular dichroism spectra for the evaluation of protein conformation

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7 January 2021

Thermal and urea-induced unfolding in T7 RNA polymerase: calorimetry, circular dichroism and fluorescence study

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7 January 2021

Theoretical Study of AqueousN-Acetyl-l-alanineN‘-Methylamide: Structures and Raman, VCD, and ROA Spectra

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7 January 2021

Growth hormone conformation and conformational equilibria.

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7 January 2021

THE ULTRAVIOLET CIRCULAR DICHROISM OF POLYPEPTIDES

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7 January 2021

Structural characterization of a partly folded apomyoglobin intermediate

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7 January 2021

Evidence for identity between the equilibrium unfolding intermediate and a transient folding intermediate: a comparative study of the folding reactions of alpha-lactalbumin and lysozyme

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7 January 2021

Two forms of the pH 4 folding intermediate of apomyoglobin

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7 January 2021

Stable submolecular folding units in a non-compact form of cytochrome c

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7 January 2021

Circular dichroism of collagen, gelatin, and poly(proline) II in the vacuum ultraviolet

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7 January 2021

Formation of a molten globule intermediate early in the kinetic folding pathway of apomyoglobin

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7 January 2021

CD and 1H-NMR studies on the conformational properties of peptide fragments from the C-terminal domain of thermolysin.

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7 January 2021

Circular dichroism of polypeptide solutions in the vacuum ultraviolet

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7 January 2021

Native-like beta-hairpin retained in the cold-denatured state of bovine beta-lactoglobulin

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7 January 2021

Vibrational circular dichroism spectroscopy of selected oligopeptide conformations

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2802%2962008-X

7 January 2021

Empirical studies of protein secondary structure by vibrational circular dichroism and related techniques. Alpha-lactalbumin and lysozyme as examples

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7 January 2021

Structure of a rapidly formed intermediate in ribonuclease T1 folding

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7 January 2021

Phi/psi-chology: Ramachandran revisited

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7 January 2021

X-ray crystallographic determination of a collagen-like peptide with the repeating sequence (Pro-Pro-Gly)

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7 January 2021

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7 January 2021

A folding model of alpha-lactalbumin deduced from the three-state denaturation mechanism

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7 January 2021

The molten globule state as a clue for understanding the folding and cooperativity of globular-protein structure.

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7 January 2021

Transient intermediates in the folding of dihydrofolate reductase as detected by far-ultraviolet circular dichroism spectroscopy.

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7 January 2021

Comparison of the transient folding intermediates in lysozyme and alpha-lactalbumin

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7 January 2021

Three-state denaturation of α-lactalbumin by guanidine hydrochloride

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7 January 2021

Rapid formation of secondary structure framework in protein folding studied by stopped-flow circular dichroism

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7 January 2021

Proteins as random coils. IV. Osmotic pressures, second virial coefficients, and unperturbed dimensions in 6M guanidine hydrochloride

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7 January 2021

Are there pathways for protein folding?

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7 January 2021

Crystal structure of poly(L-Ala-Gly)II. A model for silk. I.

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7 January 2021

Conformational analysis of a set of peptides corresponding to the entire primary sequence of the N-terminal domain of the ribosomal protein L9: evidence for stable native-like secondary structure in the unfolded state 1 1Edited by P. E. Wright

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7 January 2021

Conformation changes in the nonionizable water-soluble synthetic polypeptide poly-N5-(3-hydroxypropyl) -L-glutamine

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7 January 2021

Polyproline II helix is a key structural motif of the elastic PEVK segment of titin

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7 January 2021

Mapping the transition state and pathway of protein folding by protein engineering

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7 January 2021

The effect of temperature and salt concentration on the circular dichroism exhibited by unionized derivatives of L-alanine in aqueous solution

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7 January 2021

Conformational properties of the complexes formed by proteins and sodium dodecyl sulfate.

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7 January 2021

Functional interaction of the c-Myc transactivation domain with the TATA binding protein: evidence for an induced fit model of transactivation domain folding

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7 January 2021

Identification of initiation sites for T4 lysozyme folding using CD and NMR spectroscopy of peptide fragments.

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7 January 2021

NMR determination of residual structure in a urea-denatured protein, the 434-repressor

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7 January 2021

Circular dichroism of denatured barstar suggests residual structure,

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7 January 2021

Proteins as random coils. II. Hydrogen ion titration curve of ribonuclease in 6 M guanidine hydrochloride

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7 January 2021

‘Molten‐globule state’: a compact form of globular proteins with mobile side‐chains

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7 January 2021

The role of PII conformations in the calculation of peptide fractional helix content

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7 January 2021

Structural and Dynamical Characterization of a Biologically Active Unfolded Fibronectin-Binding Protein fromStaphylococcusaureus†

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7 January 2021

The effects of guanidine hydrochloride on the 'random coil' conformations and NMR chemical shifts of the peptide series GGXGG

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7 January 2021

Do Bridging Water Molecules Dictate the Structure of a Model Dipeptide in Aqueous Solution?

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7 January 2021

Cold denaturation of myoglobin

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7 January 2021

Heat capacity and conformation of proteins in the denatured state

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7 January 2021

Evidence for a molten globule state as a general intermediate in protein folding

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7 January 2021

The burst phase in ribonuclease A folding and solvent dependence of the unfolded state.

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7 January 2021

The folding of hen lysozyme involves partially structured intermediates and multiple pathways

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7 January 2021

The kinetic folding intermediate of ribonuclease H resembles the acid molten globule and partially unfolded molecules detected under native conditions.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2802%2962008-X

7 January 2021

Optical properties of the polyglycine II helix

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https://api.crossref.org/works/10.1016%2FS0065-3233%2802%2962008-X

7 January 2021

Spectroscopic characterization of poly(alanylglycylglycine)

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7 January 2021

The mechanism of folding of globular proteins. Equilibria and kinetics of conformational transitions of penicillinase from Staphylococcus aureus involving a state of intermediate conformation

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7 January 2021

Theoretical calculation of the circular dichroism of unordered polypeptide chains

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7 January 2021

The calculated circular dichroism of polyproline II in the polarizability approximation

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7 January 2021

Folding of a predominantly beta-structure protein: rat intestinal fatty acid binding protein.

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7 January 2021

A residue-specific NMR view of the non-cooperative unfolding of a molten globule

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7 January 2021

Different subdomains are most protected from hydrogen exchange in the molten globule and native states of human alpha-lactalbumin

1 reference

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7 January 2021

Structural and dynamical properties of a denatured protein. Heteronuclear 3D NMR experiments and theoretical simulations of lysozyme in 8 M urea

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2802%2962008-X

7 January 2021

Sequence-dependent correction of random coil NMR chemical shifts

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2802%2962008-X

7 January 2021

Random coil chemical shifts in acidic 8 M urea: implementation of random coil shift data in NMRView

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https://api.crossref.org/works/10.1016%2FS0065-3233%2802%2962008-X

7 January 2021

Dihedral angles of trialanine in D2O determined by combining FTIR and polarized visible Raman spectroscopy

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https://api.crossref.org/works/10.1016%2FS0065-3233%2802%2962008-X

7 January 2021

Comparison between the phi distribution of the amino acids in the protein database and NMR data indicates that amino acids have various phi propensities in the random coil conformation

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7 January 2021

The denatured state (the other half of the folding equation) and its role in protein stability.

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https://api.crossref.org/works/10.1016%2FS0065-3233%2802%2962008-X

7 January 2021

Persistence of native-like topology in a denatured protein in 8 M urea

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7 January 2021

Analysis of main chain torsion angles in proteins: prediction of NMR coupling constants for native and random coil conformations

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https://api.crossref.org/works/10.1016%2FS0065-3233%2802%2962008-X

7 January 2021

Solution structure of native proteins with irregular folds from Raman optical activity

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https://api.crossref.org/works/10.1016%2FS0065-3233%2802%2962008-X

7 January 2021

Poly(pro)II helices in globular proteins: identification and circular dichroic analysis

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https://api.crossref.org/works/10.1016%2FS0065-3233%2802%2962008-X

7 January 2021

A survey of left-handed polyproline II helices

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https://api.crossref.org/works/10.1016%2FS0065-3233%2802%2962008-X

7 January 2021

Folding of staphylococcal nuclease A studied by equilibrium and kinetic circular dichroism spectra

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2802%2962008-X

7 January 2021

https://api.crossref.org/works/10.1016%2FS0065-3233%2802%2962008-X

1 reference

7 January 2021

Proteins as random coils. III. Optical rotatory dispersion in 6M guanidine hydrochloride

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https://api.crossref.org/works/10.1016%2FS0065-3233%2802%2962008-X

7 January 2021

Conformational studies of a synthetic peptide corresponding to the repeat motif of C hordein

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2802%2962008-X

7 January 2021

Conformational studies of peptides corresponding to the coeliac-activating regions of wheat alpha-gliadin

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2802%2962008-X

7 January 2021

Circular dichroism of poly-L-proline in an unordered conformation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2802%2962008-X

7 January 2021

New chain conformations of poly(glutamic acid) and polylysine

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2802%2962008-X

7 January 2021

Effwct of temperature on the circular dichroism spectra of polypeptides in the extended state

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2802%2962008-X

7 January 2021

Optical rotation and the conformation of polypeptides and proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2802%2962008-X

7 January 2021

Structure characterization of the central repetitive domain of high molecular weight gluten proteins. II. Characterization in solution and in the dry state

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2802%2962008-X

7 January 2021

Structure characterization of the central repetitive domain of high molecular weight gluten proteins. I. Model studies using cyclic and linear peptides

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2802%2962008-X

7 January 2021

https://api.crossref.org/works/10.1016%2FS0065-3233%2802%2962008-X

1 reference

7 January 2021

The Key to Solving the Protein-Folding Problem Lies in an Accurate Description of the Denatured State

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2802%2962008-X

7 January 2021

The acidic activation domains of the GCN4 and GAL4 proteins are not alpha helical but form beta sheets

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2802%2962008-X

7 January 2021

Conformational analysis of peptides corresponding to beta-hairpins and a beta-sheet that represent the entire sequence of the alpha-spectrin SH3 domain.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2802%2962008-X

7 January 2021

1H, 13C and 15N random coil NMR chemical shifts of the common amino acids. I. Investigations of nearest-neighbor effects

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2802%2962008-X

7 January 2021

Cold denaturation of barstar: 1H, 15N and 13C NMR assignment and characterisation of residual structure

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2802%2962008-X

7 January 2021

Acid denaturation of bovine carbonic anhydrase B.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2802%2962008-X

7 January 2021

Structure Determination of Trialanine in Water Using Polarization Sensitive Two-Dimensional Vibrational Spectroscopy

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2802%2962008-X

7 January 2021

Intrinsically unstructured proteins: re-assessing the protein structure-function paradigm

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2802%2962008-X

7 January 2021

NMR structural and dynamic characterization of the acid-unfolded state of apomyoglobin provides insights into the early events in protein folding

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2802%2962008-X

7 January 2021

Characterization of alanine-rich peptides, Ac-(AAKAA)n-GY-NH2 (n = 1-4), using vibrational circular dichroism and Fourier transform infrared. Conformational determination and thermal unfolding

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2802%2962008-X

7 January 2021

NMR studies of unfolded states of an SH3 domain in aqueous solution and denaturing conditions

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2802%2962008-X

7 January 2021

Triple-resonance NOESY-based experiments with improved spectral resolution: applications to structural characterization of unfolded, partially folded and folded proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2802%2962008-X

7 January 2021

Comprehensive NOE characterization of a partially folded large fragment of staphylococcal nuclease Delta131Delta, using NMR methods with improved resolution.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2802%2962008-X

7 January 2021

10.1016/S0065-3233(02)62008-X

Identifiers

DOI

1 reference

5 August 2017

1 reference