A gene therapy for cancer using intramuscular injection of plasmid DNA encoding interferon alpha (Q35000575)

5 August 2017

A gene therapy for cancer using intramuscular injection of plasmid DNA encoding interferon alpha (English)

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5 August 2017

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Horton HM

1

1 reference

5 August 2017

Anderson D

2

1 reference

5 August 2017

Hernandez P

3

1 reference

5 August 2017

Barnhart KM

4

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5 August 2017

Norman JA

5

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5 August 2017

Parker SE

6

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5 August 2017

language of work or name

English

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publication date

1 February 1999

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Proceedings of the National Academy of Sciences of the United States of America

5 August 2017

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5 August 2017

96

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5 August 2017

4

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5 August 2017

1553-1558

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Plasmid DNA encoding transforming growth factor-beta1 suppresses chronic disease in a streptococcal cell wall-induced arthritis model

5 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15514

Biological properties of recombinant alpha-interferons: 40th anniversary of the discovery of interferons.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15514

Local and systemic antitumor response after combined therapy of mouse metastatic tumors with tumor cells expressing IFN-alpha and HSVtk: perspectives for the generation of cancer vaccines

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15514

Gene therapy for cancer: what have we done and where are we going?

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15514

Gene therapy in the United States: a five-year status report

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15514

Cure of mice with established metastatic friend leukemia cell tumors by a combined therapy with tumor cells expressing both interferon-alpha 1 and herpes simplex thymidine kinase followed by ganciclovir

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15514

Treatment of a human breast cancer xenograft with an adenovirus vector containing an interferon gene results in rapid regression due to viral oncolysis and gene therapy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15514

Interferon alfa-2b adjuvant therapy of high-risk resected cutaneous melanoma: the Eastern Cooperative Oncology Group Trial EST 1684.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15514

Systemic immunological effects of cytokine genes injected into skeletal muscle

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15514

Human renal carcinoma line transfected with interleukin-2 and/or interferon alpha gene(s): implications for live cancer vaccines

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15514

Cytokine therapeutics: lessons from interferon alpha

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15514

Recombinant Leukocyte A Interferon: Pharmacokinetics, Single-Dose Tolerance, and Biologic Effects in Cancer Patients

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15514

Comparison of intramuscular and intravenous recombinant alpha-2 interferon in melanoma and other cancers.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15514

Characterization of a mouse interferon gene locus I. Isolation of a cluster of four alpha interferon genes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15514

Determination of subcutaneous tumor size in athymic (nude) mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15514

Interferons and their actions

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15514

Boron neutron capture therapy for murine malignant gliomas

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15514

An improved plasmid DNA expression vector for direct injection into skeletal muscle

8 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.4.1553

Cancer Gene Therapy Using Plasmid DNA: Purification of DNA for Human Clinical Trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.4.1553

Methods for Gene Transfer Using DNA-Adenovirus Conjugates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.4.1553

Modulation of disease activity in murine systemic lupus erythematosus by cytokine gene delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.4.1553

TGF-beta1 somatic gene therapy prevents autoimmune disease in nonobese diabetic mice

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15514

Gene therapy with an adeno-associated virus carrying an interferon gene results in tumor growth suppression and regression.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15514

IFN-alpha 1 gene expression into a metastatic murine adenocarcinoma (TS/A) results in CD8+ T cell-mediated tumor rejection and development of antitumor immunity. Comparative studies with IFN-gamma-producing TS/A cells.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15514

In vivo antitumor activity of multiple injections of recombinant interleukin 2, alone and in combination with three different types of recombinant interferon, on various syngeneic murine tumors

26 October 2018

1 reference

12 December 2020

Pharmacokinetics of interferon alpha-2b in healthy volunteers

1 reference

12 December 2020

Inhibition of growth of B16 murine malignant melanoma by exogenous interferon

1 reference

12 December 2020

IFN-alpha 1 gene transfection completely abolishes the tumorigenicity of murine B16 melanoma cells in allogeneic DBA/2 mice and decreases their tumorigenicity in syngeneic C57BL/6 mice

1 reference

12 December 2020

Alpha 1-interferon gene transfer into metastatic Friend leukemia cells abrogated tumorigenicity in immunocompetent mice: antitumor therapy by means of interferon-producing cells

1 reference

12 December 2020

Intramuscular injection of expression plasmid DNA is an effective means of long-term systemic delivery of interleukin-5

1 reference

12 December 2020

Adjuvant therapy for melanoma

1 reference

12 December 2020

Orally administered IFN-alpha acts alone and in synergistic combination with intraperitoneally administered IFN-gamma to exert an antitumor effect against B16 melanoma in mice

1 reference

12 December 2020

Antiviral activities of individual murine IFN-alpha subtypes in vivo: intramuscular injection of IFN expression constructs reduces cytomegalovirus replication

1 reference

12 December 2020

Systemic delivery of interleukin 10 by intramuscular injection of expression plasmid DNA prevents autoimmune diabetes in nonobese diabetic mice

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.96.4.1553

1 reference

5 August 2017

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1 reference

5 August 2017

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