Biochemical and behavioural characterization of EMPA, a novel high-affinity, selective antagonist for the OX(2) receptor (Q35002650)

5 August 2017

title

Biochemical and behavioural characterization of EMPA, a novel high-affinity, selective antagonist for the OX(2) receptor (English)

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5 August 2017

P Malherbe

1

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5 August 2017

E Borroni

2

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5 August 2017

L Gobbi

3

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5 August 2017

H Knust

4

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5 August 2017

M Nettekoven

5

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5 August 2017

E Pinard

6

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5 August 2017

O Roche

7

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5 August 2017

M Rogers-Evans

8

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5 August 2017

J G Wettstein

9

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5 August 2017

J-L Moreau

10

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5 August 2017

language of work or name

English

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publication date

1 April 2009

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British Journal of Pharmacology

5 August 2017

published in

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5 August 2017

volume

156

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5 August 2017

issue

8

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5 August 2017

page(s)

1326-1341

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The signalling profile of recombinant human orexin-2 receptor

5 August 2017

cites work

1 reference

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8 July 2018

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The hypocretin/orexin receptor: therapeutic prospective in sleep disorders

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Comparison of the binding pockets of two chemically unrelated allosteric antagonists of the mGlu5 receptor and identification of crucial residues involved in the inverse agonism of MPEP.

8 July 2018

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8 July 2018

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Orexin A in the nucleus accumbens stimulates feeding and locomotor activity

8 July 2018

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The diurnal rhythm of hypocretin in young and old F344 rats

8 July 2018

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8 July 2018

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Characterisation of the binding of [3H]-SB-674042, a novel nonpeptide antagonist, to the human orexin-1 receptor

8 July 2018

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N-acyl 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline: the first orexin-2 receptor selective non-peptidic antagonist

8 July 2018

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Overlapping distributions of orexin/hypocretin- and dopamine-beta-hydroxylase immunoreactive fibers in rat brain regions mediating arousal, motivation, and stress

8 July 2018

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Distinct narcolepsy syndromes in Orexin receptor-2 and Orexin null mice: molecular genetic dissection of Non-REM and REM sleep regulatory processes

8 July 2018

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Orexins and their receptors: structural aspects and role in peripheral tissues.

8 July 2018

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Arousal effect of orexin A depends on activation of the histaminergic system

8 July 2018

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SB-334867-A: the first selective orexin-1 receptor antagonist

8 July 2018

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A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains

8 July 2018

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Differential distribution and regulation of OX1 and OX2 orexin/hypocretin receptor messenger RNA in the brain upon fasting.

8 July 2018

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The novel brain neuropeptide, orexin-A, modulates the sleep-wake cycle of rats

8 July 2018

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Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation

8 July 2018

1 reference

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The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene

8 July 2018

1 reference

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Distribution of orexin neurons in the adult rat brain

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2697736

Neurons containing hypocretin (orexin) project to multiple neuronal systems

8 July 2018

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Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior

8 July 2018

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The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity

8 July 2018

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Haplotype analysis confirms the association between the HCRTR2 gene and cluster headache

8 July 2018

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Guide to Receptors and Channels (GRAC), 3rd edition

26 October 2018

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Inhibitory effects of an orexin-2 receptor antagonist on orexin A- and stress-induced ACTH responses in conscious rats

26 October 2018

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Orexin, drugs and motivated behaviors

26 October 2018

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A role for lateral hypothalamic orexin neurons in reward seeking

26 October 2018

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Centrally administered orexin-A activates corticotropin-releasing factor-containing neurons in the hypothalamic paraventricular nucleus and central amygdaloid nucleus of rats: possible involvement of central orexins on stress-activated central CRF n

26 October 2018

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Single cns neurons link both central motor and cardiosympathetic systems: a double-virus tracing study

26 October 2018

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Development of an orexin-2 receptor selective agonist, [Ala(11), D-Leu(15)]orexin-B.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2697736

Protein distribution of the orexin-2 receptor in the rat central nervous system

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2697736

Orexins activate histaminergic neurons via the orexin 2 receptor

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2697736

Fluctuation of extracellular hypocretin-1 (orexin A) levels in the rat in relation to the light-dark cycle and sleep-wake activities

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2697736

Differential expression of orexin receptors 1 and 2 in the rat brain

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2697736

Diurnal variation in orexin A immunoreactivity and prepro-orexin mRNA in the rat central nervous system.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2697736

Hypocretin (orexin) deficiency in human narcolepsy.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2697736

Distribution of orexin receptor mRNA in the rat brain

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2697736

Possible involvement of orexin in the stress reaction in rats

26 October 2018

1 reference

12 December 2020

Orexin-induced hyperlocomotion and stereotypy are mediated by the dopaminergic system

1 reference

12 December 2020

Exclusive postsynaptic action of hypocretin-orexin on sublayer 6b cortical neurons

1 reference

12 December 2020

Interaction between the corticotropin-releasing factor system and hypocretins (orexins): a novel circuit mediating stress response

1 reference

12 December 2020

10.1111/J.1476-5381.2009.00127.X

Identifiers

DOI

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5 August 2017

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5 August 2017

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