AIDS vaccines and preexposure prophylaxis: is synergy possible? (Q35003539)

5 August 2017

title

AIDS vaccines and preexposure prophylaxis: is synergy possible? (English)

1 reference

5 August 2017

9

Eduard J Sanders

1 reference

5 August 2017

7

Omu Anzala

1 reference

5 August 2017

6

Anatoli Kamali

1 reference

5 August 2017

1

Jean-Louis Excler

1 reference

5 August 2017

5

Adrian B McDermott

1 reference

5 August 2017

11

Seth Berkley

1 reference

5 August 2017

Wasima Rida

2

1 reference

5 August 2017

Frances Priddy

3

1 reference

5 August 2017

Jill Gilmour

4

1 reference

5 August 2017

Gaudensia Mutua

8

1 reference

5 August 2017

Wayne Koff

10

1 reference

5 August 2017

Patricia Fast

12

1 reference

5 August 2017

publication date

16 December 2010

1 reference

AIDS Research and Human Retroviruses

5 August 2017

published in

1 reference

5 August 2017

volume

27

1 reference

5 August 2017

issue

6

1 reference

5 August 2017

page(s)

669-680

1 reference

Cohorts for the study of HIV‐1-exposed but uninfected individuals: benefits and limitations

5 August 2017

cites work

1 reference

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Initiation of antiretroviral therapy 48 hours after infection with simian immunodeficiency virus potently suppresses acute-phase viremia and blocks the massive loss of memory CD4+ T cells but fails to prevent disease

8 July 2018

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Low-dose rectal inoculation of rhesus macaques by SIVsmE660 or SIVmac251 recapitulates human mucosal infection by HIV-1.

8 July 2018

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Side effects of long-term oral antiviral therapy for hepatitis B.

8 July 2018

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Sexual transmission of HIV according to viral load and antiretroviral therapy: systematic review and meta-analysis

8 July 2018

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CLSI-derived hematology and biochemistry reference intervals for healthy adults in eastern and southern Africa

8 July 2018

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Tenofovir use is associated with an increase in serum alkaline phosphatase in the Swiss HIV Cohort Study.

8 July 2018

1 reference

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Reference intervals in healthy adult Ugandan blood donors and their impact on conducting international vaccine trials

8 July 2018

1 reference

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Universal voluntary HIV testing with immediate antiretroviral therapy as a strategy for elimination of HIV transmission: a mathematical model

8 July 2018

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Mucosal prior to systemic application of recombinant adenovirus boosting is more immunogenic than systemic application twice but confers similar protection against SIV-challenge in DNA vaccine-primed macaques.

8 July 2018

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Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial

8 July 2018

1 reference

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Challenges in the development of an HIV-1 vaccine

8 July 2018

1 reference

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Drug-susceptible HIV-1 infection despite intermittent fixed-dose combination tenofovir/emtricitabine as prophylaxis is associated with low-level viremia, delayed seroconversion, and an attenuated clinical course

8 July 2018

1 reference

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Prevention of SIV rectal transmission and priming of T cell responses in macaques after local pre-exposure application of tenofovir gel

8 July 2018

1 reference

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Less is more, except when less is less: Studying joint effects

8 July 2018

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Nonhuman primate models and the failure of the Merck HIV-1 vaccine in humans

8 July 2018

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8 July 2018

Toward an AIDS vaccine

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The impact of pre-exposure prophylaxis (PrEP) on HIV epidemics in Africa and India: a simulation study.

8 July 2018

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Prevention of rectal SHIV transmission in macaques by daily or intermittent prophylaxis with emtricitabine and tenofovir

8 July 2018

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The pharmacokinetics and viral activity of tenofovir in the male genital tract

8 July 2018

1 reference

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Amplified transmission of HIV-1: comparison of HIV-1 concentrations in semen and blood during acute and chronic infection

8 July 2018

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8 July 2018

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Narrative review: antiretroviral therapy to prevent the sexual transmission of HIV-1.

8 July 2018

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Postexposure prophylaxis after sexual exposure to HIV.

8 July 2018

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Strong HIV-1-specific T cell responses in HIV-1-exposed uninfected infants and neonates revealed after regulatory T cell removal

8 July 2018

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The case for expanding access to highly active antiretroviral therapy to curb the growth of the HIV epidemic

8 July 2018

1 reference

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Vaccine-induced cellular immune responses reduce plasma viral concentrations after repeated low-dose challenge with pathogenic simian immunodeficiency virus SIVmac239

8 July 2018

1 reference

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Perils at mucosal front lines for HIV and SIV and their hosts

8 July 2018

1 reference

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Propagation and dissemination of infection after vaginal transmission of simian immunodeficiency virus

8 July 2018

1 reference

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Measurement of intracellular didanosine and tenofovir phosphorylated metabolites and possible interaction of the two drugs in human immunodeficiency virus-infected patients

8 July 2018

1 reference

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Rates of HIV-1 transmission per coital act, by stage of HIV-1 infection, in Rakai, Uganda

8 July 2018

1 reference

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Diminished replicative fitness of primary human immunodeficiency virus type 1 isolates harboring the K65R mutation

8 July 2018

1 reference

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Pharmacokinetic and pharmacodynamic characteristics of emtricitabine support its once daily dosing for the treatment of HIV infection

8 July 2018

1 reference

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CD8+-cell-mediated suppression of virulent simian immunodeficiency virus during tenofovir treatment

8 July 2018

1 reference

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Repeated low-dose mucosal simian immunodeficiency virus SIVmac239 challenge results in the same viral and immunological kinetics as high-dose challenge: a model for the evaluation of vaccine efficacy in nonhuman primates

8 July 2018

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Early Control of Highly Pathogenic Simian Immunodeficiency Virus/Human Immunodeficiency Virus Chimeric Virus Infections in Rhesus Monkeys Usually Results in Long-Lasting Asymptomatic Clinical Outcomes

8 July 2018

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Stochastic simulation of the impact of antiretroviral therapy and HIV vaccines on HIV transmission; Rakai, Uganda

8 July 2018

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Recent observations on HIV type-1 infection in the genital tract of men and women

8 July 2018

1 reference

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Male viral load and heterosexual transmission of HIV-1 subtype E in northern Thailand

8 July 2018

1 reference

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Role of CD8(+) lymphocytes in control of simian immunodeficiency virus infection and resistance to rechallenge after transient early antiretroviral treatment

8 July 2018

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Phase i/ii trial of the pharmacokinetics, safety, and antiretroviral activity of tenofovir disoproxil fumarate in human immunodeficiency virus-infected adults

8 July 2018

1 reference

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Virologic and immunologic determinants of heterosexual transmission of human immunodeficiency virus type 1 in Africa.

8 July 2018

1 reference

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Transient antiretroviral treatment during acute simian immunodeficiency virus infection facilitates long-term control of the virus

8 July 2018

1 reference

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Enhanced cellular immune response and reduced CD8(+) lymphocyte apoptosis in acutely SIV-infected Rhesus macaques after short-term antiretroviral treatment

8 July 2018

1 reference

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Suppression of acute viremia by short-term postexposure prophylaxis of simian/human immunodeficiency virus SHIV-RT-infected monkeys with a novel reverse transcriptase inhibitor (GW420867) allows for development of potent antiviral immune responses r

8 July 2018

1 reference

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Viral load and heterosexual transmission of human immunodeficiency virus type 1. Rakai Project Study Group

8 July 2018

1 reference

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Containment of simian immunodeficiency virus infection: cellular immune responses and protection from rechallenge following transient postinoculation antiretroviral treatment

8 July 2018

1 reference

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Antiretroviral therapy during primary immunodeficiency virus infection can induce persistent suppression of virus load and protection from heterologous challenge in rhesus macaques.

8 July 2018

1 reference

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HIV-1-specific mucosal CD8+ lymphocyte responses in the cervix of HIV-1-resistant prostitutes in Nairobi.

8 July 2018

1 reference

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9-[2-(Phosphonomethoxy)propyl]adenine (PMPA) therapy prolongs survival of infant macaques inoculated with simian immunodeficiency virus with reduced susceptibility to PMPA

8 July 2018

1 reference

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Early short-term 9-[2-(R)-(phosphonomethoxy)propyl]adenine treatment favorably alters the subsequent disease course in simian immunodeficiency virus-infected newborn Rhesus macaques.

8 July 2018

1 reference

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Cytotoxic T cell responses to multiple conserved HIV epitopes in HIV-resistant prostitutes in Nairobi

8 July 2018

1 reference

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Effectiveness of postinoculation (R)-9-(2-phosphonylmethoxypropyl) adenine treatment for prevention of persistent simian immunodeficiency virus SIVmne infection depends critically on timing of initiation and duration of treatment

8 July 2018

1 reference

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Anti-human immunodeficiency virus activity and cellular metabolism of a potential prodrug of the acyclic nucleoside phosphonate 9-R-(2-phosphonomethoxypropyl)adenine (PMPA), Bis(isopropyloxymethylcarbonyl)PMPA

8 July 2018

1 reference

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A case-control study of HIV seroconversion in health care workers after percutaneous exposure. Centers for Disease Control and Prevention Needlestick Surveillance Group

8 July 2018

1 reference

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Sexual transmission of HIV.

8 July 2018

1 reference

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Prevention of SIV infection in macaques by (R)-9-(2-phosphonylmethoxypropyl)adenine

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101085

The 2 x 2 factorial design: its application to a randomized trial of aspirin and carotene in U.S. physicians

8 July 2018

1 reference

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HIV viral set point and host immune control in individuals with HIV-specific CD8+ T-cell responses prior to HIV acquisition

8 July 2018

1 reference

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Low-level exposure to HIV induces virus-specific T cell responses and immune activation in exposed HIV-seronegative individuals.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101085

Repeated rectal SHIVSF162P3 exposures do not consistently induce sustained T cell responses prior to systemic infection in the repeat-low dose preclinical macaque model

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101085

Expanded access to highly active antiretroviral therapy: a potentially powerful strategy to curb the growth of the HIV epidemic

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101085

Short communication: no evidence of occult SHIV infection as demonstrated by CD8+ cell depletion after chemoprophylaxis-induced protection from mucosal infection in rhesus macaques

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101085

Protection of macaques against vaginal SHIV challenge by systemic or mucosal and systemic vaccinations with HIV-envelope

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101085

Comparative evaluation of oral and intranasal priming with replication-competent adenovirus 5 host range mutant (Ad5hr)-simian immunodeficiency virus (SIV) recombinant vaccines on immunogenicity and protective efficacy against SIV(mac251).

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101085

The public health impact of widespread availability of nonoccupational postexposure prophylaxis against HIV.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101085

Evolution of innate and adaptive effector cell functions during acute HIV-1 infection

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101085

A comparison of eight methods for the dual-endpoint evaluation of efficacy in a proof-of-concept HIV vaccine trial.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101085

Chemoprophylaxis with tenofovir disoproxil fumarate provided partial protection against infection with simian human immunodeficiency virus in macaques given multiple virus challenges

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101085

Intracellular pharmacokinetics of tenofovir diphosphate, carbovir triphosphate, and lamivudine triphosphate in patients receiving triple-nucleoside regimens

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101085

The clinical benefits of tenofovir for simian immunodeficiency virus-infected macaques are larger than predicted by its effects on standard viral and immunologic parameters.

26 October 2018

1 reference

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Transient early post‐inoculation anti‐retroviral treatment facilitates controlled infection with sparing of CD4+ T cells in gut‐associated lymphoid tissues in SIVmac239‐infected rhesus macaques, but not resistance to rechallenge

26 October 2018

1 reference

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Tenofovir DF in antiretroviral-experienced patients: results from a 48-week, randomized, double-blind study

26 October 2018

1 reference

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Two low doses of tenofovir protect newborn macaques against oral simian immunodeficiency virus infection

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101085

Viral burden in genital secretions determines male-to-female sexual transmission of HIV-1: a probabilistic empiric model

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101085

Development of virus-specific immune responses in SHIV(KU)-infected macaques treated with PMPA.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101085

Administration of 9-[2-(phosphonomethoxy)propyl]adenine (PMPA) for prevention of perinatal simian immunodeficiency virus infection in rhesus macaques

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101085

Some statistical issues in HIV vaccine trials.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101085

The ‘immunologic advantage’ of HIV-exposed seronegative individuals

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101085

Post-exposure chemoprophylaxis (PECP) against SIV infection of macaques as a model for protection from HIV infection

9 December 2018

1 reference

12 December 2020

Mucosal Exposure to Subinfectious Doses of SIV Primes Gut-Associated Antibody-Secreting Cells and T Cells: Lack of Enhancement by Nonneutralizing Antibody

1 reference

12 December 2020

Estimating the benefit of an HIV-1 vaccine that reduces viral load set point

1 reference

12 December 2020

A strategy for accelerating the development of preventive AIDS vaccines

1 reference

12 December 2020

Can antiretroviral therapy eliminate HIV transmission?

1 reference

12 December 2020

Universal voluntary testing and treatment for prevention of HIV transmission

1 reference

12 December 2020

Persistent HIV RNA shedding in semen despite effective antiretroviral therapy

1 reference

12 December 2020

Accelerating HIV vaccine development

1 reference

12 December 2020

Costs of eliminating HIV in South Africa have been underestimated

1 reference

12 December 2020

Identifiers

DOI

10.1089/AID.2010.0206

1 reference

5 August 2017

1 reference

5 August 2017

1 reference