Implications of high RNA virus mutation rates: lethal mutagenesis and the antiviral drug ribavirin (Q35005247)

5 August 2017

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title

Implications of high RNA virus mutation rates: lethal mutagenesis and the antiviral drug ribavirin (English)

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5 August 2017

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2

Raul Andino

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5 August 2017

1

Shane Crotty

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5 August 2017

1 November 2002

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5 August 2017

Microbes and Infection

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5 August 2017

4

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5 August 2017

13

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5 August 2017

1301-1307

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Broad-spectrum antiviral activity of Virazole: 1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide

5 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2900008-4

7 January 2021

Ribavirin's antiviral mechanism of action: lethal mutagenesis?

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2900008-4

7 January 2021

Interferon alfa-2b alone or in combination with ribavirin for the treatment of relapse of chronic hepatitis C. International Hepatitis Interventional Therapy Group

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2900008-4

7 January 2021

Interferon alfa-2b alone or in combination with ribavirin as initial treatment for chronic hepatitis C. Hepatitis Interventional Therapy Group

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https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2900008-4

7 January 2021

Lassa fever. Effective therapy with ribavirin

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7 January 2021

Interferon and ribavirin vs interferon alone in the re-treatment of chronic hepatitis C previously nonresponsive to interferon: A meta-analysis of randomized trials.

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2900008-4

7 January 2021

The broad-spectrum antiviral ribonucleoside ribavirin is an RNA virus mutagen

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2900008-4

7 January 2021

RNA virus error catastrophe: direct molecular test by using ribavirin

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2900008-4

7 January 2021

Mechanism of action of 1- -D-ribofuranosyl-1,2,4-triazole-3-carboxamide (Virazole), a new broad-spectrum antiviral agent

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2900008-4

7 January 2021

Poliovirus RNA-dependent RNA polymerase (3D(pol)). Assembly of stable, elongation-competent complexes by using a symmetrical primer-template substrate (sym/sub)

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7 January 2021

Poliovirus RNA-dependent RNA polymerase (3Dpol): structural, biochemical, and biological analysis of conserved structural motifs A and B

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7 January 2021

Mutation Frequencies at Defined Single Codon Sites in Vesicular Stomatitis Virus and Poliovirus Can Be Increased Only Slightly by Chemical Mutagenesis

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7 January 2021

Ribavirin Induces Error-Prone Replication of GB Virus B in Primary Tamarin Hepatocytes

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7 January 2021

Distribution of spontaneous mutants and inferences about the replication mode of the RNA bacteriophage phi6.

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7 January 2021

An analysis of the clone size distribution of ΦX174 mutants and recombinants

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7 January 2021

The frequency distribution of spontaneous bacteriophage mutants as evidence for the exponential rate of phage reproduction

1 reference

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7 January 2021

Mutation rates among RNA viruses

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7 January 2021

Long term trends in the evolution of H(3) HA1 human influenza type A

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7 January 2021

Response of foot-and-mouth disease virus to increased mutagenesis: influence of viral load and fitness in loss of infectivity

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7 January 2021

Viral kinetics and mathematical models

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7 January 2021

Eventual AIDS vaccine failure in a rhesus monkey by viral escape from cytotoxic T lymphocytes

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7 January 2021

Late escape from an immunodominant cytotoxic T-lymphocyte response associated with progression to AIDS

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7 January 2021

Studies on the infectivity of foot-and-mouth disease virus RNA using microinjection

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7 January 2021

Mutants of Sindbis virus. II. Characterization of a maturation-defective mutant, ts103.

1 reference

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7 January 2021

Lethal mutagenesis of HIV with mutagenic nucleoside analogs

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7 January 2021

Rapid evolution of RNA genomes

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7 January 2021

Fitness of RNA virus decreased by Muller's ratchet

1 reference

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7 January 2021

The mechanism of RNA recombination in poliovirus

1 reference

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7 January 2021

Evolutionary aspects of recombination in RNA viruses

1 reference

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7 January 2021

Clustered charged-to-alanine mutagenesis of poliovirus RNA-dependent RNA polymerase yields multiple temperature-sensitive mutants defective in RNA synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2900008-4

7 January 2021

Proteinase trapping: screening for viral proteinase mutants by alpha complementation

1 reference

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7 January 2021

Antigenic drift in the influenza A virus (H3N2) nucleoprotein and escape from recognition by cytotoxic T lymphocytes

1 reference

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7 January 2021

The outcome of hepatitis C virus infection is predicted by escape mutations in epitopes targeted by cytotoxic T lymphocytes

1 reference

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7 January 2021

Viral escape by selection of cytotoxic T cell-resistant virus variants in vivo

1 reference

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7 January 2021

Hepatitis C virus RNA-dependent RNA polymerase (NS5B) as a mediator of the antiviral activity of ribavirin

1 reference

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7 January 2021

10.1016/S1286-4579(02)00008-4

Identifiers

DOI

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5 August 2017

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PubMed ID

12443894