PPARδ agonists have opposing effects on insulin resistance in high fat-fed rats and mice due to different metabolic responses in muscle (Q35005682)

5 August 2017

title

PPARδ agonists have opposing effects on insulin resistance in high fat-fed rats and mice due to different metabolic responses in muscle (English)

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5 August 2017

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Xiao-Yi Zeng

4

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Nigel Turner

object named as

Nigel Turner

3

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Gregory J. Cooney

6

object named as

Gregory J Cooney

1 reference

5 August 2017

9

Edward W Kraegen

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5 August 2017

Ji-Ming Ye

1

1 reference

5 August 2017

Jennifer Tid-Ang

2

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5 August 2017

Hai-Yan Li

5

1 reference

5 August 2017

Erik Max Wulff

7

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5 August 2017

Per Sauerberg

8

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5 August 2017

language of work or name

English

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publication date

1 June 2011

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British Journal of Pharmacology

5 August 2017

published in

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5 August 2017

volume

163

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5 August 2017

issue

3

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5 August 2017

page(s)

556-566

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Oral administration of a PPAR-delta agonist to rodents worsens, not improves, maximal insulin-stimulated glucose transport in skeletal muscle of different fibers

5 August 2017

cites work

1 reference

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Improved insulin sensitivity and islet function after PPARdelta activation in diabetic db/db mice

8 July 2018

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Enhancement of muscle mitochondrial oxidative capacity and alterations in insulin action are lipid species dependent: potent tissue-specific effects of medium-chain fatty acids

8 July 2018

1 reference

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AMPK and PPARdelta agonists are exercise mimetics

8 July 2018

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Peroxisome proliferator-activated receptor-delta induces insulin-induced gene-1 and suppresses hepatic lipogenesis in obese diabetic mice

8 July 2018

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Islet-1: a potentially important role for an islet cell gene in visceral fat.

8 July 2018

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Activation of peroxisome proliferator-activated receptor (PPAR)delta promotes reversal of multiple metabolic abnormalities, reduces oxidative stress, and increases fatty acid oxidation in moderately obese men.

8 July 2018

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The PPARdelta agonist, GW501516, promotes fatty acid oxidation but has no direct effect on glucose utilisation or insulin sensitivity in rat L6 skeletal muscle cells

8 July 2018

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Identification and synthesis of a novel selective partial PPARdelta agonist with full efficacy on lipid metabolism in vitro and in vivo

8 July 2018

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Usefulness of the 5' region of the cDNA encoding acidic ribosomal phosphoprotein P0 conserved among rats, mice, and humans as a standard probe for gene expression analysis in different tissues and animal species

8 July 2018

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Liver-specific inhibition of ChREBP improves hepatic steatosis and insulin resistance in ob/ob mice.

8 July 2018

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Reversal of diet-induced hepatic steatosis and hepatic insulin resistance by antisense oligonucleotide inhibitors of acetyl-CoA carboxylases 1 and 2.

8 July 2018

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Peroxisome proliferator-activated receptor delta promotes very low-density lipoprotein-derived fatty acid catabolism in the macrophage

8 July 2018

1 reference

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Improved glucose homeostasis and enhanced insulin signalling in Grb14-deficient mice

8 July 2018

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Activation of peroxisome proliferator-activated receptor delta induces fatty acid beta-oxidation in skeletal muscle and attenuates metabolic syndrome

8 July 2018

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Peroxisome-Proliferator-Activated Receptor δ Activates Fat Metabolism to Prevent Obesity

8 July 2018

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A selective peroxisome proliferator-activated receptor delta agonist promotes reverse cholesterol transport

8 July 2018

1 reference

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In vivo glucose metabolism in individual tissues of the rat. Interaction between epinephrine and insulin.

8 July 2018

1 reference

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Development of muscle insulin resistance after liver insulin resistance in high-fat-fed rats

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101618

PPARdelta agonism inhibits skeletal muscle PDC activity, mitochondrial ATP production and force generation during prolonged contraction.

8 July 2018

1 reference

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PPAR alpha, more than PPAR delta, mediates the hepatic and skeletal muscle alterations induced by the PPAR agonist GW0742.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01240.X

AICAR administration causes an apparent enhancement of muscle and liver insulin action in insulin-resistant high-fat-fed rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01240.X

Development of muscle insulin resistance after liver insulin resistance in high-fat-fed rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01240.X

PPARdelta activator GW-501516 has no acute effect on glucose transport in skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01240.X

Berberine and its more biologically available derivative, dihydroberberine, inhibit mitochondrial respiratory complex I: a mechanism for the action of berberine to activate AMP-activated protein kinase and improve insulin action

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01240.X

PPARalpha /gamma ragaglitazar eliminates fatty liver and enhances insulin action in fat-fed rats in the absence of hepatomegaly

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01240.X

Guide to Receptors and Channels (GRAC), 4th Edition

21 January 2018

1 reference

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Rosiglitazone Treatment Enhances Acute AMP-Activated Protein Kinase-Mediated Muscle and Adipose Tissue Glucose Uptake in High-Fat-Fed Rats

26 October 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01240.X

PPARdelta agonism induces a change in fuel metabolism and activation of an atrophy programme, but does not impair mitochondrial function in rat skeletal muscle

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21265823

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Selective PPARdelta agonist treatment increases skeletal muscle lipid metabolism without altering mitochondrial energy coupling: an in vivo magnetic resonance spectroscopy study

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21265823

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1111/J.1476-5381.2011.01240.X

1 reference

5 August 2017

1 reference

5 August 2017

1 reference