Topical microbicides to prevent the transmission of HIV: formulation gaps and challenges (Q35009798)

5 August 2017

title

Topical microbicides to prevent the transmission of HIV: formulation gaps and challenges (English)

1 reference

5 August 2017

0 references

Jim A Turpin

1

1 reference

5 August 2017

publication date

21 May 2011

1 reference

Drug delivery and translational research

5 August 2017

published in

1 reference

5 August 2017

volume

1

1 reference

5 August 2017

issue

3

1 reference

5 August 2017

page(s)

194-200

1 reference

https://scigraph.springernature.com/pub.10.1007/s13346-011-0034-2

5 August 2017

exact match

0 references

cites work

Mucosal human defensins 5 and 6 antagonize the anti-HIV activity of candidate polyanion microbicides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102847

Clinical evaluation of microbicide formulations

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102847

Advances in microbicide vaginal rings

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102847

Preclinical evaluation of anti-HIV microbicide products: New models and biomarkers

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102847

Microbicide excipients can greatly increase susceptibility to genital herpes transmission in the mouse

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102847

Early events in sexual transmission of HIV and SIV and opportunities for interventions

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102847

Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102847

Protection of rhesus macaques from vaginal infection by vaginally delivered maraviroc, an inhibitor of HIV-1 entry via the CCR5 co-receptor

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102847

Sex hormone regulation of innate immunity in the female reproductive tract: the role of epithelial cells in balancing reproductive potential with protection against sexually transmitted pathogens.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102847

Targeting early infection to prevent HIV-1 mucosal transmission.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102847

Postcoital bioavailability and antiviral activity of 0.5% PRO 2000 gel: implications for future microbicide clinical trials

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102847

Nanoparticles reveal that human cervicovaginal mucus is riddled with pores larger than viruses

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102847

Human immunodeficiency virus type 1 is trapped by acidic but not by neutralized human cervicovaginal mucus

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102847

Disruption of tight junctions by cellulose sulfate facilitates HIV infection: model of microbicide safety

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102847

Prospective study of correlates of vaginal Lactobacillus colonisation among high-risk HIV-1 seronegative women

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102847

Glycerol monolaurate prevents mucosal SIV transmission

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102847

HIV infection of the genital mucosa in women.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102847

Barrier properties of mucus

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102847

Mucus-penetrating nanoparticles for drug and gene delivery to mucosal tissues

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102847

Targeted delivery of PSC-RANTES for HIV-1 prevention using biodegradable nanoparticles.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102847

Glycerol monolaurate does not alter rhesus macaque (Macaca mulatta) vaginal lactobacilli and is safe for chronic use

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102847

A new strategy to understand how HIV infects women: identification of a window of vulnerability during the menstrual cycle

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102847

Lack of effectiveness of cellulose sulfate gel for the prevention of vaginal HIV transmission

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102847

Enhancement of HIV infection by cellulose sulfate

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102847

Seminal plasma reduces the effectiveness of topical polyanionic microbicides

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102847

In vitro and in vivo: the story of nonoxynol 9.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102847

Recommendations for the nonclinical development of topical microbicides for prevention of HIV transmission: an update

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102847

Shifts in condom use following microbicide introduction: should we be concerned?

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102847

Effectiveness of COL-1492, a nonoxynol-9 vaginal gel, on HIV-1 transmission in female sex workers: a randomised controlled trial

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102847

Practical prevention of vaginal and rectal transmission of HIV by adapting the oral defense: use of commercial lubricants

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102847

Recommendations for the clinical development of topical microbicides: an update

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102847

Evaluating the potential impact of vaginal microbicides to reduce the risk of acquiring HIV in female sex workers.

8 July 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-011-0034-2

Protection of macaques from vaginal SHIV challenge by vaginally delivered inhibitors of virus-cell fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-011-0034-2

Vaginal lactobacilli, microbial flora, and risk of human immunodeficiency virus type 1 and sexually transmitted disease acquisition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-011-0034-2

Bacterial vaginosis and susceptibility to HIV infection in South African women: a nested case-control study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-011-0034-2

Efficacy of Carraguard for prevention of HIV infection in women in South Africa: a randomised, double-blind, placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-011-0034-2

Preventing sexual transmission of HIV: anti-HIV bioregulatory and homeostatic components of commercial sexual lubricants.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102847

Bacterial vaginosis and disturbances of vaginal flora

26 October 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-011-0034-2

In vitro and in vivo characterization of a potential universal placebo designed for use in vaginal microbicide clinical trials

21 January 2018

1 reference

12 December 2020

Trends in microbicide formulations workshop

1 reference

12 December 2020

Bacterial vaginosis and disturbances of vaginal flora: association with increased acquisition of HIV

1 reference

12 December 2020

Hyperosmolar sexual lubricant causes epithelial damage in the distal colon: potential implication for HIV transmission

1 reference

12 December 2020

10.1007/S13346-011-0034-2

Identifiers

DOI

1 reference

5 August 2017

1 reference

5 August 2017

1 reference