The B lineage transcription factor E2A regulates apoptosis in chronic lymphocytic leukemia (CLL) cells (Q35011166)

5 August 2017

title

The B lineage transcription factor E2A regulates apoptosis in chronic lymphocytic leukemia (CLL) cells (English)

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chronic lymphocytic leukemia

5 August 2017

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Lela Kardava

1

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5 August 2017

Qi Yang

2

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5 August 2017

Anthony St Leger

3

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5 August 2017

Kenneth A Foon

4

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5 August 2017

Suzanne Lentzsch

5

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5 August 2017

Abbe N Vallejo

6

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5 August 2017

Christine Milcarek

7

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5 August 2017

Lisa Borghesi

8

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5 August 2017

publication date

6 May 2011

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5 August 2017

published in

International Immunology

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5 August 2017

volume

23

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5 August 2017

issue

6

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5 August 2017

page(s)

375-384

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E47 regulates hematopoietic stem cell proliferation and energetics but not myeloid lineage restriction

5 August 2017

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CD38 expression labels an activated subset within chronic lymphocytic leukemia clones enriched in proliferating B cells

8 July 2018

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Efficient nucleofection of primary human B cells and B-CLL cells induces apoptosis, which depends on the microenvironment and on the structure of transfected nucleic acids

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Intrinsic inhibition of transcription factor E2A by HLH proteins ABF-1 and Id2 mediates reprogramming of neoplastic B cells in Hodgkin lymphoma

8 July 2018

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E47 is required for V(D)J recombinase activity in common lymphoid progenitors

8 July 2018

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8 July 2018

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Gene expression profiling of E2F-1-induced apoptosis.

8 July 2018

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Receptor editing and marginal zone B cell development are regulated by the helix-loop-helix protein, E2A

8 July 2018

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8 July 2018

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B-cell chronic lymphocytic leukemia cells express a surface membrane phenotype of activated, antigen-experienced B lymphocytes

8 July 2018

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Gene expression profiling of B cell chronic lymphocytic leukemia reveals a homogeneous phenotype related to memory B cells.

8 July 2018

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E2A activity is induced during B-cell activation to promote immunoglobulin class switch recombination

8 July 2018

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8 July 2018

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E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements

8 July 2018

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The helix-loop-helix gene E2A is required for B cell formation

8 July 2018

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A novel type of p53 pathway dysfunction in chronic lymphocytic leukemia resulting from two interacting single nucleotide polymorphisms within the p21 gene

8 July 2018

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Concurrent up-regulation of BCL-XL and BCL2A1 induces approximately 1000-fold resistance to ABT-737 in chronic lymphocytic leukemia

25 October 2018

1 reference

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Mcl-1 expression has in vitro and in vivo significance in chronic lymphocytic leukemia and is associated with other poor prognostic markers.

25 October 2018

1 reference

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BCR ligation induced by IgM stimulation results in gene expression and functional changes only in IgV H unmutated chronic lymphocytic leukemia (CLL) cells.

25 October 2018

1 reference

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Aging down-regulates the transcription factor E2A, activation-induced cytidine deaminase, and Ig class switch in human B cells

25 October 2018

1 reference

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Id3 induces growth arrest and caspase-2-dependent apoptosis in B lymphocyte progenitors

25 October 2018

1 reference

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ZAP-70 compared with immunoglobulin heavy-chain gene mutation status as a predictor of disease progression in chronic lymphocytic leukemia

25 October 2018

1 reference

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Reduced Ig class switch in aged mice correlates with decreased E47 and activation-induced cytidine deaminase

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103389

Fludarabine-induced apoptosis of B chronic lymphocytic leukemia cells includes early cleavage of p27kip1 by caspases

25 October 2018

1 reference

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E-proteins directly regulate expression of activation-induced deaminase in mature B cells

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103389

Cycling B-CLL cells are highly susceptible to inhibition of the proteasome: involvement of p27, early D-type cyclins, Bax, and caspase-dependent and -independent pathways

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103389

Clinical significance of CD38 expression in chronic lymphocytic leukemia

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103389

Thalidomide and its analogs overcome drug resistance of human multiple myeloma cells to conventional therapy.

25 October 2018

1 reference

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Prognostic significance of the cell cycle inhibitor p27Kip1 in chronic B-cell lymphocytic leukemia.

25 October 2018

1 reference

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Evaluation of CDKN2C/p18, CDKN1B/p27 and CDKN2B/p15 mRNA expression, and CpG methylation status in sporadic and MEN1-associated pancreatic endocrine tumours

25 October 2018

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12 December 2020

Constitutively activated Notch signaling is involved in survival and apoptosis resistance of B-CLL cells

1 reference

12 December 2020

Initiation of antigen receptor-dependent differentiation into plasma cells by calmodulin inhibition of E2A

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12 December 2020

Multivariate analysis of prognostic factors in CLL: clinical stage, IGVH gene mutational status, and loss or mutation of the p53 gene are independent prognostic factors

1 reference

12 December 2020

Expression profiling of B cell chronic lymphocytic leukemia suggests deficient CD1-mediated immunity, polarized cytokine response, altered adhesion and increased intracellular protein transport and processing of leukemic cells

1 reference

12 December 2020

Decreased E12 and/or E47 transcription factor activity in the bone marrow as well as in the spleen of aged mice

1 reference

12 December 2020

Nuclear NF-ATp is a hallmark of unstimulated B cells from B-CLL patients

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12 December 2020

Identifiers

DOI

10.1093/INTIMM/DXR027

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5 August 2017

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5 August 2017

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