Repeated TLR9 stimulation results in macrophage activation syndrome-like disease in mice. (Q35015661)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21576823%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

title

Repeated TLR9 stimulation results in macrophage activation syndrome-like disease in mice (English)

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1 February 2020

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2

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Edward M Behrens

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1 February 2020

author name string

Katharine Slade

3

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1 February 2020

Sheila Rao

4

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1 February 2020

Portia A Kreiger

5

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1 February 2020

Michele Paessler

6

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1 February 2020

Taku Kambayashi

7

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1 February 2020

Gary A Koretzky

8

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language of work or name

English

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publication date

16 May 2011

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Journal of Clinical Investigation

1 February 2020

published in

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volume

121

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1 February 2020

issue

6

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1 February 2020

page(s)

2264-2277

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Gene expression profiling of peripheral blood mononuclear cells from children with active hemophagocytic lymphohistiocytosis

1 February 2020

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Regulation of autoreactive B cell responses to endogenous TLR ligands

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Secondary hemophagocytic lymphohistiocytosis and severe sepsis/ systemic inflammatory response syndrome/multiorgan dysfunction syndrome/macrophage activation syndrome share common intermediate phenotypes on a spectrum of inflammation

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The vIL-10 gene of the Epstein-Barr virus (EBV) is conserved in a stable manner except for a few point mutations in various EBV isolates

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Notch-RBP-J signaling controls the homeostasis of CD8- dendritic cells in the spleen.

8 July 2018

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Jinx, an MCMV susceptibility phenotype caused by disruption of Unc13d: a mouse model of type 3 familial hemophagocytic lymphohistiocytosis

8 July 2018

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Occult macrophage activation syndrome in patients with systemic juvenile idiopathic arthritis.

8 July 2018

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Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus.

8 July 2018

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8 July 2018

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Cytokine storm in a phase 1 trial of the anti-CD28 monoclonal antibody TGN1412

8 July 2018

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CpG-induced tyrosine phosphorylation occurs via a TLR9-independent mechanism and is required for cytokine secretion

8 July 2018

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An animal model of hemophagocytic lymphohistiocytosis (HLH): CD8+ T cells and interferon gamma are essential for the disorder

8 July 2018

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Lymphoid follicle destruction and immunosuppression after repeated CpG oligodeoxynucleotide administration

8 July 2018

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Constitutive Cytokine mRNAs Mark Natural Killer (NK) and NK T Cells Poised for Rapid Effector Function

8 July 2018

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Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

8 July 2018

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Thrombocytopenia in the sepsis syndrome: role of hemophagocytosis and macrophage colony-stimulating factor

8 July 2018

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8 July 2018

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CpG motifs in bacterial DNA trigger direct B-cell activation

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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25 October 2018

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Gene expression profiling of peripheral blood from patients with untreated new-onset systemic juvenile idiopathic arthritis reveals molecular heterogeneity that may predict macrophage activation syndrome

25 October 2018

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Constitutive endocytosis of CD163 mediates hemoglobin-heme uptake and determines the noninflammatory and protective transcriptional response of macrophages to hemoglobin

25 October 2018

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25 October 2018

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Reactive hemophagocytic syndrome--a clinicopathologic study of 40 patients in an Oriental population

25 October 2018

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Role of TLR9 in anti-nucleosome and anti-DNA antibody production in lpr mutation-induced murine lupus

25 October 2018

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12 December 2020

The diagnostic significance of soluble CD163 and soluble interleukin-2 receptor alpha-chain in macrophage activation syndrome and untreated new-onset systemic juvenile idiopathic arthritis

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12 December 2020

TLR9 contributes to antiviral immunity during gammaherpesvirus infection

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12 December 2020

Association study of a single nucleotide polymorphism in the exon 2 region of toll-like receptor 9 (TLR9) gene with susceptibility to systemic lupus erythematosus among Chinese

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12 December 2020

Consumption coagulopathy associated with systemic juvenile rheumatoid arthritis

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12 December 2020

Disseminated intravascular coagulation complicating systemic juvenile chronic arthritis ("Still's disease")

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12 December 2020

Evidence for intravascular coagulation in systemic onset, but not polyarticular, juvenile rheumatoid arthritis

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12 December 2020

Histiocytic hemophagocytosis in the bone marrow in children with sepsis and disseminated intravascular coagulation

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12 December 2020

Hypercytokinemia in hemophagocytic syndrome

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12 December 2020

Cytokine production regulating Th1 and Th2 cytokines in hemophagocytic lymphohistiocytosis

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12 December 2020

Phenotypic and functional profiling of human proinflammatory type-1 and anti-inflammatory type-2 macrophages in response to microbial antigens and IFN-gamma- and CD40L-mediated costimulation

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12 December 2020

Identifiers

DOI

10.1172/JCI43157

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21576823%20AND%20SRC:MED&resulttype=core&format=json

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1 February 2020

Fatcat ID

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Fatcat

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24 November 2022

mapped directly with Wikidata item

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21576823%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

PubMed publication ID

21576823

1 reference