"Nutritional and chemopreventive anti-cancer agents up-regulate expression of p27Kip1, a cyclin-dependent kinase inhibitor, in mouse JB6 epidermal and human MCF7, MDA-MB-321 and AU565 breast cancer cells". (Q35016172)

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Language	Label	Description	Also known as
English	"Nutritional and chemopreventive anti-cancer agents up-regulate expression of p27Kip1, a cyclin-dependent kinase inhibitor, in mouse JB6 epidermal and human MCF7, MDA-MB-321 and AU565 breast cancer cells".	scientific article

Statements

scholarly article

1 reference

Europe PubMed Central

5 August 2017

"Nutritional and chemopreventive anti-cancer agents up-regulate expression of p27Kip1, a cyclin-dependent kinase inhibitor, in mouse JB6 epidermal and human MCF7, MDA-MB-321 and AU565 breast cancer cells". (English)

1 reference

Europe PubMed Central

5 August 2017

author name string

Isao Eto

1

1 reference

Europe PubMed Central

5 August 2017

publication date

9 August 2006

1 reference

Europe PubMed Central

5 August 2017

Cancer Cell International

1 reference

Europe PubMed Central

5 August 2017

6

1 reference

Europe PubMed Central

5 August 2017

20

1 reference

Europe PubMed Central

5 August 2017

https://scigraph.springernature.com/pub.10.1186/1475-2867-6-20

0 references

Metformin inhibits cytokine-induced nuclear factor kappaB activation via AMP-activated protein kinase activation in vascular endothelial cells

1 reference

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AMP-activated protein kinase (AMPK) activating agents cause dephosphorylation of Akt and glycogen synthase kinase-3.

1 reference

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Fibronectin stimulates non-small cell lung carcinoma cell growth through activation of Akt/mammalian target of rapamycin/S6 kinase and inactivation of LKB1/AMP-activated protein kinase signal pathways

1 reference

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AMPK activation regulates apoptosis, adipogenesis, and lipolysis by eIF2alpha in adipocytes

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5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside inhibits cancer cell proliferation in vitro and in vivo via AMP-activated protein kinase

1 reference

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Atrophy of S6K1(-/-) skeletal muscle cells reveals distinct mTOR effectors for cell cycle and size control.

1 reference

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Processing the message: structural insights into capping and decapping mRNA.

1 reference

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1 reference

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The polynucleotide ligase and RNA capping enzyme superfamily of covalent nucleotidyltransferases.

1 reference

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The AMP-activated protein kinase pathway--new players upstream and downstream.

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1 reference

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AMP-activated protein kinase: the guardian of cardiac energy status.

1 reference

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Epigallocatechin-3-gallate inhibits epidermal growth factor receptor signaling pathway. Evidence for direct inhibition of ERK1/2 and AKT kinases.

1 reference

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Epigallocatechin-3-gallate inhibits activation of HER-2/neu and downstream signaling pathways in human head and neck and breast carcinoma cells.

1 reference

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Cell cycle-dependent translation of p27 involves a responsive element in its 5'-UTR that overlaps with a uORF

1 reference

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Expression of constitutively active 4EBP-1 enhances p27Kip1 expression and inhibits proliferation of MCF7 breast cancer cells

1 reference

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8 July 2018

ELAV/Hu proteins inhibit p27 translation via an IRES element in the p27 5'UTR.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1559648

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The protein kinase B/Akt signalling pathway in human malignancy

1 reference

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Tangled webs: evidence of cross-talk between c-Raf-1 and Akt.

1 reference

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Consequences of mevalonate depletion. Differential transcriptional, translational, and post-translational up-regulation of Ras, Rap1a, RhoA, AND RhoB.

1 reference

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Role of AMP-activated protein kinase in mechanism of metformin action

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Negative regulation of protein translation by mitogen-activated protein kinase-interacting kinases 1 and 2

1 reference

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Control of cyclin-dependent kinase inhibitor p27 expression by cap-independent translation

1 reference

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Transformation nonresponsive cells owe their resistance to lack of p65/nuclear factor-kappaB activation

1 reference

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The ends of the affair: capping and polyadenylation.

1 reference

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A U-rich element in the 5' untranslated region is necessary for the translation of p27 mRNA.

1 reference

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Molecular cloning and characterization of the human p27Kip1 gene promoter

1 reference

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1 reference

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Enhanced ribosomal association of p27(Kip1) mRNA is a mechanism contributing to accumulation during growth arrest.

1 reference

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Repression of p27kip1 synthesis by platelet-derived growth factor in BALB/c 3T3 cells

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Translational control of p27Kip1 accumulation during the cell cycle

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Structure and cell cycle-regulated transcription of the human cyclin A gene

1 reference

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1 reference

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Activation of the AMP-activated kinase by antidiabetes drug metformin stimulates nitric oxide synthesis in vivo by promoting the association of heat shock protein 90 and endothelial nitric oxide synthase

1 reference

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1 reference

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Akt activates the mammalian target of rapamycin by regulating cellular ATP level and AMPK activity

1 reference

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PD98059 and U0126 activate AMP-activated protein kinase by increasing the cellular AMP:ATP ratio and not via inhibition of the MAP kinase pathway.

1 reference

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1 reference

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1 reference

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Activation of cardiac AMP-activated protein kinase by LKB1 expression or chemical hypoxia is blunted by increased Akt activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/16899133

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A second RING to destroy p27(Kip1)

1 reference

https://pubmed.ncbi.nlm.nih.gov/16899133

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1475-2867-6-20

1 reference

Europe PubMed Central

5 August 2017

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0 references

1 reference

Europe PubMed Central

5 August 2017

1 reference

Europe PubMed Central

5 August 2017

ResearchGate publication ID

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