A human vitamin D receptor mutant activated by cholecalciferol (Q35017142)

5 August 2017

title

A human vitamin D receptor mutant activated by cholecalciferol (English)

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5 August 2017

0 references

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Amanda M Ousley

1

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5 August 2017

Hilda S Castillo

2

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5 August 2017

Anna Duraj-Thatte

3

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5 August 2017

Donald F Doyle

4

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5 August 2017

Bahareh Azizi

5

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5 August 2017

publication date

10 March 2011

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The Journal of Steroid Biochemistry and Molecular Biology

5 August 2017

published in

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5 August 2017

volume

125

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5 August 2017

issue

3-5

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5 August 2017

page(s)

202-210

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Characterization of a molecular switch system that regulates gene expression in mammalian cells through a small molecule

5 August 2017

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New insights into Vitamin D sterol-VDR proteolysis, allostery, structure-function from the perspective of a conformational ensemble model

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Molecular and functional comparison of 1,25-dihydroxyvitamin D(3) and the novel vitamin D receptor ligand, lithocholic acid, in activating transcription of cytochrome P450 3A4.

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Molecular modeling, affinity labeling, and site-directed mutagenesis define the key points of interaction between the ligand-binding domain of the vitamin D nuclear receptor and 1 alpha,25-dihydroxyvitamin D3.

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Hereditary vitamin D resistant rickets caused by a novel mutation in the vitamin D receptor that results in decreased affinity for hormone and cellular hyporesponsiveness

8 July 2018

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8 July 2018

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The high affinity ligand binding conformation of the nuclear 1,25-dihydroxyvitamin D3 receptor is functionally linked to the transactivation domain 2 (AF-2)

8 July 2018

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Examination of the potential functional role of conserved cysteine residues in the hormone binding domain of the human 1,25-dihydroxyvitamin D3 receptor.

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Production of a functional eukaryotic enzyme in Escherichia coli: cloning and expression of the yeast structural gene for imidazole-glycerolphosphate dehydratase (his3)

8 July 2018

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Molecular structure of the rat vitamin D receptor ligand binding domain complexed with 2-carbon-substituted vitamin D3 hormone analogues and a LXXLL-containing coactivator peptide

8 July 2018

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Crystal structures of the vitamin D nuclear receptor liganded with the vitamin D side chain analogues calcipotriol and seocalcitol, receptor agonists of clinical importance. Insights into a structural basis for the switching of calcipotriol to a rec

25 October 2018

1 reference

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Chemical complementation: small-molecule-based genetic selection in yeast

25 October 2018

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The unique tryptophan residue of the vitamin D receptor is critical for ligand binding and transcriptional activation

25 October 2018

1 reference

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The nuclear receptor ligand-binding domain: structure and function

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3105188

Structure-function studies of new C-20 epimer pairs of vitamin D3 analogs

25 October 2018

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12 December 2020

Ligand Recognition by Vitamin D Receptor: Total Alanine Scanning Mutational Analysis of the Residues Lining the Ligand Binding Pocket of Vitamin D Receptor

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12 December 2020

Probing a Water Channel near the A-Ring of Receptor-Bound 1α,25-Dihydroxyvitamin D3 with Selected 2α-Substituted Analogues†

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12 December 2020

Residues of the human nuclear vitamin D receptor that form hydrogen bonding interactions with the three hydroxyl groups of 1alpha,25-dihydroxyvitamin D3

1 reference

12 December 2020

10.1016/J.JSBMB.2011.03.001

Identifiers

DOI

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5 August 2017

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5 August 2017

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